EA022283B1 - Лекарственный препарат, содержащий бензилдиметил[3-(миристоиламино)пропил]аммония хлорид - Google Patents
Лекарственный препарат, содержащий бензилдиметил[3-(миристоиламино)пропил]аммония хлорид Download PDFInfo
- Publication number
- EA022283B1 EA022283B1 EA201201158A EA201201158A EA022283B1 EA 022283 B1 EA022283 B1 EA 022283B1 EA 201201158 A EA201201158 A EA 201201158A EA 201201158 A EA201201158 A EA 201201158A EA 022283 B1 EA022283 B1 EA 022283B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- propyl
- myristoylamino
- drug according
- dimethyl
- amine
- Prior art date
Links
- JQQZCIIDNVIQKO-UHFFFAOYSA-N benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC1=CC=CC=C1 JQQZCIIDNVIQKO-UHFFFAOYSA-N 0.000 title claims abstract description 14
- 150000004682 monohydrates Chemical group 0.000 claims abstract description 9
- 239000003814 drug Substances 0.000 claims description 44
- 229940079593 drug Drugs 0.000 claims description 40
- 241001465754 Metazoa Species 0.000 claims description 25
- -1 dimethyl [3- (myristoylamino) propyl] amine Chemical class 0.000 claims description 24
- 239000002674 ointment Substances 0.000 claims description 14
- 239000008024 pharmaceutical diluent Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- 230000002421 anti-septic effect Effects 0.000 claims description 6
- 239000007787 solid Substances 0.000 claims description 5
- CNIIGCLFLJGOGP-UHFFFAOYSA-N 2-(1-naphthalenylmethyl)-4,5-dihydro-1H-imidazole Chemical compound C=1C=CC2=CC=CC=C2C=1CC1=NCCN1 CNIIGCLFLJGOGP-UHFFFAOYSA-N 0.000 claims description 4
- HUCJFAOMUPXHDK-UHFFFAOYSA-N Xylometazoline Chemical compound CC1=CC(C(C)(C)C)=CC(C)=C1CC1=NCCN1 HUCJFAOMUPXHDK-UHFFFAOYSA-N 0.000 claims description 4
- 235000019270 ammonium chloride Nutrition 0.000 claims description 4
- 229940064004 antiseptic throat preparations Drugs 0.000 claims description 4
- 239000000850 decongestant Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- WYWIFABBXFUGLM-UHFFFAOYSA-N oxymetazoline Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C)=C1CC1=NCCN1 WYWIFABBXFUGLM-UHFFFAOYSA-N 0.000 claims description 3
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 claims description 2
- UBCHPRBFMUDMNC-UHFFFAOYSA-N 1-(1-adamantyl)ethanamine Chemical compound C1C(C2)CC3CC2CC1(C(N)C)C3 UBCHPRBFMUDMNC-UHFFFAOYSA-N 0.000 claims description 2
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 claims description 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims description 2
- 229960004150 aciclovir Drugs 0.000 claims description 2
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 claims description 2
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- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 claims description 2
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- DLNKOYKMWOXYQA-UHFFFAOYSA-N dl-pseudophenylpropanolamine Natural products CC(N)C(O)C1=CC=CC=C1 DLNKOYKMWOXYQA-UHFFFAOYSA-N 0.000 claims description 2
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- GGXMRPUKBWXVHE-MIHLVHIWSA-N halometasone Chemical compound C1([C@@H](F)C2)=CC(=O)C(Cl)=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]2(C)C[C@@H]1O GGXMRPUKBWXVHE-MIHLVHIWSA-N 0.000 claims description 2
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- DLNKOYKMWOXYQA-APPZFPTMSA-N phenylpropanolamine Chemical compound C[C@@H](N)[C@H](O)C1=CC=CC=C1 DLNKOYKMWOXYQA-APPZFPTMSA-N 0.000 claims description 2
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- GOZBHBFUQHMKQB-UHFFFAOYSA-N trimecaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=C(C)C=C1C GOZBHBFUQHMKQB-UHFFFAOYSA-N 0.000 claims description 2
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- 229960001334 corticosteroids Drugs 0.000 claims 1
- 229960001347 fluocinolone acetonide Drugs 0.000 claims 1
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- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
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| PCT/EP2010/001056 WO2011100994A1 (de) | 2010-02-19 | 2010-02-19 | Arzneimittel enthaltend myramistin |
| PCT/EP2011/000691 WO2011101113A1 (de) | 2010-02-19 | 2011-02-15 | Arzneimittel enthaltend myramistin |
Publications (2)
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| EA201201158A1 EA201201158A1 (ru) | 2013-02-28 |
| EA022283B1 true EA022283B1 (ru) | 2015-12-30 |
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| EA201201158A EA022283B1 (ru) | 2010-02-19 | 2011-02-15 | Лекарственный препарат, содержащий бензилдиметил[3-(миристоиламино)пропил]аммония хлорид |
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| JP (1) | JP5746224B2 (enExample) |
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| PT (1) | PT2536400E (enExample) |
| SI (1) | SI2536400T1 (enExample) |
| UA (1) | UA103968C2 (enExample) |
| WO (2) | WO2011100994A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2014175757A1 (ru) * | 2013-04-22 | 2014-10-30 | Общество с ограниченной ответственностью "Нанобиотех" | Антисептический ветеринарный препарат и способы его использования |
| RU2542376C1 (ru) * | 2013-07-30 | 2015-02-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Средство для лечения гнойно-воспалительных процессов мягких тканей и слизистых оболочек |
| CN109456218A (zh) * | 2018-12-17 | 2019-03-12 | 山东诚汇双达药业有限公司 | 一种盐酸三甲卡因的生产方法 |
| GB202003240D0 (en) * | 2020-03-05 | 2020-04-22 | Ecosynth Nv | Antiviral treatment |
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| US4093711A (en) * | 1976-08-13 | 1978-06-06 | Noxell Corporation | Oral hygiene |
| WO1993000892A1 (fr) * | 1991-07-10 | 1993-01-21 | Jury Semenovich Krivoshein | Preparation pharmaceutique |
| SU1796185A1 (ru) * | 1990-06-23 | 1993-02-23 | Adolina P Rudko | Фунгицид 2 |
| RU2157214C2 (ru) * | 1998-04-16 | 2000-10-10 | Государственный научный центр лекарственных средств | Противовоспалительное и антимикробное лекарственное средство для местного применения |
| RU2161961C1 (ru) * | 2000-03-17 | 2001-01-20 | Кривошеин Юрий Семенович | Лекарственный препарат |
| UA64800C2 (uk) * | 2000-04-27 | 2004-03-15 | Юрій Семенович Кривошеін | Очний антисептик |
| US20040058924A1 (en) * | 2000-12-20 | 2004-03-25 | Schlitzer Ronald L. | Use of amidoamines to treat or prevent acanthamoeba and fungal infections |
| UA67795C2 (uk) * | 2000-06-26 | 2004-07-15 | Yurii Semenovych Kryvoshein | Склад для лікування опікових ран, який включає мірамістин |
| EP1634590A1 (de) * | 2003-06-04 | 2006-03-15 | Megainpharm GmbH | Coronavirus-inaktivierendes mittel |
| WO2007136558A2 (en) * | 2006-05-10 | 2007-11-29 | S.K. Pharmaceutical, Inc. | Synergistically enhanced disinfecting solutions |
| DE102008039254A1 (de) * | 2008-08-20 | 2010-02-25 | Megainpharm Gmbh | Arzneimittel |
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| US5393491A (en) | 1993-09-22 | 1995-02-28 | Alcon Laboratories, Inc. | Use of amidoamines in ophthalmic compositions |
| UA30143C2 (uk) * | 1997-12-30 | 2001-11-15 | Юрій Семенович Кривошеін | Лікувальний препарат для профілактики та лікування інфекційних та запальних захворювань |
| RU2177314C2 (ru) | 2000-03-22 | 2001-12-27 | Кривошеин Юрий Семенович | Состав с антисептическими, репаративными и болеутоляющими свойствами |
| RU2173142C1 (ru) | 2000-04-18 | 2001-09-10 | Кривошеин Юрий Семенович | Вагинальный контрацептив |
| RU2184534C2 (ru) | 2000-04-27 | 2002-07-10 | Рудько Адолина Петровна | Антисептические таблетки |
| RU2185156C2 (ru) | 2000-06-26 | 2002-07-20 | Рудько Адолина Петровна | Интраназальный антисептик |
| RU2188005C2 (ru) | 2000-10-04 | 2002-08-27 | Рудько Адолина Петровна | Состав для антисептической обработки кожи рук и операционного поля |
| US20040033208A1 (en) | 2000-12-20 | 2004-02-19 | Cagle Gerald D. | Antifungal compositions containing an antibiotic and one or more amidoamines |
| WO2002049627A2 (en) * | 2000-12-20 | 2002-06-27 | Alcon, Inc. | Antifungal compositions containing an antibiotic and one or more amidoamines |
| RU2005100533A (ru) * | 2005-01-13 | 2006-06-20 | Открытое акционерное общество "Система-Венчур" (ОАО "Система-Венчур") (RU) | Средство для ускорения заживления раны |
| CN101562971A (zh) * | 2006-05-10 | 2009-10-21 | S.K.药物公司 | 协同增强的消毒溶液 |
| CN101100432B (zh) * | 2006-07-04 | 2010-08-04 | 中国人民解放军军事医学科学院毒物药物研究所 | 苯甲基二甲基[3-(肉豆蔻酰胺基)丙基]氯化铵的合成方法 |
| DE102008039234A1 (de) * | 2007-10-29 | 2009-05-07 | Neudecker & Jolitz Gmbh & Co. | Motorisch betriebener Türöffner und Motor für einen Türöffner |
| UA30143U (en) | 2007-11-14 | 2008-02-11 | Валерий Михайлович Шарапов | Piezoelectric transformer |
-
2010
- 2010-02-19 WO PCT/EP2010/001056 patent/WO2011100994A1/de not_active Ceased
-
2011
- 2011-02-15 CN CN201180014472.7A patent/CN102869354B/zh active Active
- 2011-02-15 ES ES11708184.4T patent/ES2524379T3/es active Active
- 2011-02-15 BR BR112012020828-4A patent/BR112012020828B1/pt not_active IP Right Cessation
- 2011-02-15 PT PT117081844T patent/PT2536400E/pt unknown
- 2011-02-15 WO PCT/EP2011/000691 patent/WO2011101113A1/de not_active Ceased
- 2011-02-15 AU AU2011217530A patent/AU2011217530B2/en active Active
- 2011-02-15 DK DK11708184.4T patent/DK2536400T3/en active
- 2011-02-15 HR HRP20141173AT patent/HRP20141173T1/hr unknown
- 2011-02-15 JP JP2012553213A patent/JP5746224B2/ja active Active
- 2011-02-15 KR KR1020127024396A patent/KR101744895B1/ko active Active
- 2011-02-15 MX MX2012009646A patent/MX2012009646A/es active IP Right Grant
- 2011-02-15 MD MDA20120079A patent/MD4411C1/ro active IP Right Grant
- 2011-02-15 EP EP11708184.4A patent/EP2536400B1/de active Active
- 2011-02-15 SI SI201130337T patent/SI2536400T1/sl unknown
- 2011-02-15 GE GEAP201112831A patent/GEP20135942B/en unknown
- 2011-02-15 EA EA201201158A patent/EA022283B1/ru unknown
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- 2011-02-15 PL PL11708184T patent/PL2536400T3/pl unknown
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2012
- 2012-08-16 IL IL221501A patent/IL221501A/en active IP Right Grant
-
2014
- 2014-12-11 CY CY20141101033T patent/CY1115833T1/el unknown
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2459062A (en) * | 1944-02-08 | 1949-01-11 | American Cyanamid Co | Quaternary ammonium compounds |
| US4093711A (en) * | 1976-08-13 | 1978-06-06 | Noxell Corporation | Oral hygiene |
| SU1796185A1 (ru) * | 1990-06-23 | 1993-02-23 | Adolina P Rudko | Фунгицид 2 |
| WO1993000892A1 (fr) * | 1991-07-10 | 1993-01-21 | Jury Semenovich Krivoshein | Preparation pharmaceutique |
| RU2157214C2 (ru) * | 1998-04-16 | 2000-10-10 | Государственный научный центр лекарственных средств | Противовоспалительное и антимикробное лекарственное средство для местного применения |
| RU2161961C1 (ru) * | 2000-03-17 | 2001-01-20 | Кривошеин Юрий Семенович | Лекарственный препарат |
| UA64800C2 (uk) * | 2000-04-27 | 2004-03-15 | Юрій Семенович Кривошеін | Очний антисептик |
| UA67795C2 (uk) * | 2000-06-26 | 2004-07-15 | Yurii Semenovych Kryvoshein | Склад для лікування опікових ран, який включає мірамістин |
| US20040058924A1 (en) * | 2000-12-20 | 2004-03-25 | Schlitzer Ronald L. | Use of amidoamines to treat or prevent acanthamoeba and fungal infections |
| EP1634590A1 (de) * | 2003-06-04 | 2006-03-15 | Megainpharm GmbH | Coronavirus-inaktivierendes mittel |
| WO2007136558A2 (en) * | 2006-05-10 | 2007-11-29 | S.K. Pharmaceutical, Inc. | Synergistically enhanced disinfecting solutions |
| DE102008039254A1 (de) * | 2008-08-20 | 2010-02-25 | Megainpharm Gmbh | Arzneimittel |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2536400A1 (de) | 2012-12-26 |
| CY1115833T1 (el) | 2017-01-25 |
| GEP20135942B (en) | 2013-10-10 |
| ES2524379T3 (es) | 2014-12-05 |
| KR101744895B1 (ko) | 2017-06-08 |
| JP5746224B2 (ja) | 2015-07-08 |
| BR112012020828B1 (pt) | 2021-01-12 |
| JP2013519695A (ja) | 2013-05-30 |
| WO2011101113A1 (de) | 2011-08-25 |
| MX2012009646A (es) | 2013-02-11 |
| EP2536400B1 (de) | 2014-09-24 |
| PT2536400E (pt) | 2014-11-27 |
| AU2011217530B2 (en) | 2014-01-16 |
| WO2011100994A1 (de) | 2011-08-25 |
| BR112012020828A2 (pt) | 2016-06-28 |
| DK2536400T3 (en) | 2014-12-15 |
| KR20130018242A (ko) | 2013-02-20 |
| HK1179164A1 (zh) | 2013-09-27 |
| CN102869354A (zh) | 2013-01-09 |
| PL2536400T3 (pl) | 2015-04-30 |
| MD20120079A2 (en) | 2013-01-31 |
| MD4411B1 (ro) | 2016-04-30 |
| HRP20141173T1 (hr) | 2015-01-30 |
| UA103968C2 (ru) | 2013-12-10 |
| AU2011217530A1 (en) | 2012-09-13 |
| SI2536400T1 (sl) | 2015-01-30 |
| CN102869354B (zh) | 2015-12-16 |
| EA201201158A1 (ru) | 2013-02-28 |
| IL221501A (en) | 2016-11-30 |
| MD4411C1 (ro) | 2016-11-30 |
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