CN102869354B - 包含肉豆蔻酰氨基丙基二甲基苄基氯化铵的药物制剂 - Google Patents

包含肉豆蔻酰氨基丙基二甲基苄基氯化铵的药物制剂 Download PDF

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Publication number
CN102869354B
CN102869354B CN201180014472.7A CN201180014472A CN102869354B CN 102869354 B CN102869354 B CN 102869354B CN 201180014472 A CN201180014472 A CN 201180014472A CN 102869354 B CN102869354 B CN 102869354B
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pharmaceutical
pharmaceutical preparation
propyl
pharmaceutical formulation
myristoylamino
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CN102869354A (zh
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A·鲁德科
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MEGAINPHARM GmbH
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MEGAINPHARM GmbH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/14Quaternary ammonium compounds, e.g. edrophonium, choline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0046Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Otolaryngology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201180014472.7A 2010-02-19 2011-02-15 包含肉豆蔻酰氨基丙基二甲基苄基氯化铵的药物制剂 Active CN102869354B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2010/001056 2010-02-19
PCT/EP2010/001056 WO2011100994A1 (de) 2010-02-19 2010-02-19 Arzneimittel enthaltend myramistin
PCT/EP2011/000691 WO2011101113A1 (de) 2010-02-19 2011-02-15 Arzneimittel enthaltend myramistin

Publications (2)

Publication Number Publication Date
CN102869354A CN102869354A (zh) 2013-01-09
CN102869354B true CN102869354B (zh) 2015-12-16

Family

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CN201180014472.7A Active CN102869354B (zh) 2010-02-19 2011-02-15 包含肉豆蔻酰氨基丙基二甲基苄基氯化铵的药物制剂

Country Status (20)

Country Link
EP (1) EP2536400B1 (enExample)
JP (1) JP5746224B2 (enExample)
KR (1) KR101744895B1 (enExample)
CN (1) CN102869354B (enExample)
AU (1) AU2011217530B2 (enExample)
BR (1) BR112012020828B1 (enExample)
CY (1) CY1115833T1 (enExample)
DK (1) DK2536400T3 (enExample)
EA (1) EA022283B1 (enExample)
ES (1) ES2524379T3 (enExample)
GE (1) GEP20135942B (enExample)
HR (1) HRP20141173T1 (enExample)
IL (1) IL221501A (enExample)
MD (1) MD4411C1 (enExample)
MX (1) MX2012009646A (enExample)
PL (1) PL2536400T3 (enExample)
PT (1) PT2536400E (enExample)
SI (1) SI2536400T1 (enExample)
UA (1) UA103968C2 (enExample)
WO (2) WO2011100994A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014175757A1 (ru) * 2013-04-22 2014-10-30 Общество с ограниченной ответственностью "Нанобиотех" Антисептический ветеринарный препарат и способы его использования
RU2542376C1 (ru) * 2013-07-30 2015-02-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации Средство для лечения гнойно-воспалительных процессов мягких тканей и слизистых оболочек
CN109456218A (zh) * 2018-12-17 2019-03-12 山东诚汇双达药业有限公司 一种盐酸三甲卡因的生产方法
GB202003240D0 (en) * 2020-03-05 2020-04-22 Ecosynth Nv Antiviral treatment

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2459062A (en) * 1944-02-08 1949-01-11 American Cyanamid Co Quaternary ammonium compounds
US4093711A (en) * 1976-08-13 1978-06-06 Noxell Corporation Oral hygiene
US20040058924A1 (en) * 2000-12-20 2004-03-25 Schlitzer Ronald L. Use of amidoamines to treat or prevent acanthamoeba and fungal infections
CN1798553A (zh) * 2003-06-04 2006-07-05 梅根医药股份有限公司 冠状病毒灭活剂
CN101100432A (zh) * 2006-07-04 2008-01-09 中国人民解放军军事医学科学院毒物药物研究所 苯甲基二甲基[3-(肉豆蔻酰胺基)丙基]氯化铵的合成方法
CN101562971A (zh) * 2006-05-10 2009-10-21 S.K.药物公司 协同增强的消毒溶液

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
SU1796185A1 (ru) 1990-06-23 1993-02-23 Adolina P Rudko Фунгицид 2
WO1993000892A1 (fr) 1991-07-10 1993-01-21 Jury Semenovich Krivoshein Preparation pharmaceutique
US5393491A (en) 1993-09-22 1995-02-28 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
UA30143C2 (uk) * 1997-12-30 2001-11-15 Юрій Семенович Кривошеін Лікувальний препарат для профілактики та лікування інфекційних та запальних захворювань
RU2157214C2 (ru) 1998-04-16 2000-10-10 Государственный научный центр лекарственных средств Противовоспалительное и антимикробное лекарственное средство для местного применения
RU2161961C1 (ru) * 2000-03-17 2001-01-20 Кривошеин Юрий Семенович Лекарственный препарат
RU2177314C2 (ru) 2000-03-22 2001-12-27 Кривошеин Юрий Семенович Состав с антисептическими, репаративными и болеутоляющими свойствами
RU2173142C1 (ru) 2000-04-18 2001-09-10 Кривошеин Юрий Семенович Вагинальный контрацептив
RU2164135C1 (ru) 2000-04-27 2001-03-20 Рудько Адолина Петровна Глазной антисептик
RU2184534C2 (ru) 2000-04-27 2002-07-10 Рудько Адолина Петровна Антисептические таблетки
RU2185157C2 (ru) 2000-06-26 2002-07-20 Рудько Адолина Петровна Средство для лечения ожоговых ран
RU2185156C2 (ru) 2000-06-26 2002-07-20 Рудько Адолина Петровна Интраназальный антисептик
RU2188005C2 (ru) 2000-10-04 2002-08-27 Рудько Адолина Петровна Состав для антисептической обработки кожи рук и операционного поля
US20040033208A1 (en) 2000-12-20 2004-02-19 Cagle Gerald D. Antifungal compositions containing an antibiotic and one or more amidoamines
WO2002049627A2 (en) * 2000-12-20 2002-06-27 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
RU2005100533A (ru) * 2005-01-13 2006-06-20 Открытое акционерное общество "Система-Венчур" (ОАО "Система-Венчур") (RU) Средство для ускорения заживления раны
US20070264226A1 (en) 2006-05-10 2007-11-15 Karagoezian Hampar L Synergistically enhanced disinfecting solutions
DE102008039234A1 (de) * 2007-10-29 2009-05-07 Neudecker & Jolitz Gmbh & Co. Motorisch betriebener Türöffner und Motor für einen Türöffner
UA30143U (en) 2007-11-14 2008-02-11 Валерий Михайлович Шарапов Piezoelectric transformer
DE102008039254A1 (de) * 2008-08-20 2010-02-25 Megainpharm Gmbh Arzneimittel

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2459062A (en) * 1944-02-08 1949-01-11 American Cyanamid Co Quaternary ammonium compounds
US4093711A (en) * 1976-08-13 1978-06-06 Noxell Corporation Oral hygiene
US20040058924A1 (en) * 2000-12-20 2004-03-25 Schlitzer Ronald L. Use of amidoamines to treat or prevent acanthamoeba and fungal infections
CN1798553A (zh) * 2003-06-04 2006-07-05 梅根医药股份有限公司 冠状病毒灭活剂
CN101562971A (zh) * 2006-05-10 2009-10-21 S.K.药物公司 协同增强的消毒溶液
CN101100432A (zh) * 2006-07-04 2008-01-09 中国人民解放军军事医学科学院毒物药物研究所 苯甲基二甲基[3-(肉豆蔻酰胺基)丙基]氯化铵的合成方法

Also Published As

Publication number Publication date
MD4411C1 (ro) 2016-11-30
BR112012020828B1 (pt) 2021-01-12
PT2536400E (pt) 2014-11-27
KR20130018242A (ko) 2013-02-20
BR112012020828A2 (pt) 2016-06-28
PL2536400T3 (pl) 2015-04-30
JP5746224B2 (ja) 2015-07-08
SI2536400T1 (sl) 2015-01-30
KR101744895B1 (ko) 2017-06-08
EA201201158A1 (ru) 2013-02-28
AU2011217530A1 (en) 2012-09-13
GEP20135942B (en) 2013-10-10
CN102869354A (zh) 2013-01-09
UA103968C2 (ru) 2013-12-10
WO2011100994A1 (de) 2011-08-25
AU2011217530B2 (en) 2014-01-16
HK1179164A1 (zh) 2013-09-27
WO2011101113A1 (de) 2011-08-25
EA022283B1 (ru) 2015-12-30
MX2012009646A (es) 2013-02-11
IL221501A (en) 2016-11-30
DK2536400T3 (en) 2014-12-15
CY1115833T1 (el) 2017-01-25
HRP20141173T1 (hr) 2015-01-30
EP2536400B1 (de) 2014-09-24
EP2536400A1 (de) 2012-12-26
ES2524379T3 (es) 2014-12-05
MD20120079A2 (en) 2013-01-31
MD4411B1 (ro) 2016-04-30
JP2013519695A (ja) 2013-05-30

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