KR101653555B1 - 단백질의 분비 생산 방법 - Google Patents

단백질의 분비 생산 방법 Download PDF

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Publication number
KR101653555B1
KR101653555B1 KR1020147015040A KR20147015040A KR101653555B1 KR 101653555 B1 KR101653555 B1 KR 101653555B1 KR 1020147015040 A KR1020147015040 A KR 1020147015040A KR 20147015040 A KR20147015040 A KR 20147015040A KR 101653555 B1 KR101653555 B1 KR 101653555B1
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protein
ala
ser
thr
leu
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KR20140088215A (ko
Inventor
요시히코 마쓰다
히로시 이타야
요시미 기쿠치
하루키 벳푸
유르기스 안타나스 블라도비치 요만타스
에카테리나 알렉산드로브나 쿠투코바
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아지노모토 가부시키가이샤
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020147015040A 2011-11-02 2012-11-01 단백질의 분비 생산 방법 Active KR101653555B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2011240745 2011-11-02
JPJP-P-2011-240745 2011-11-02
RU2011144497/10A RU2011144497A (ru) 2011-11-02 2011-11-02 Способ секреторного получения белка
RU2011144497 2011-11-02
PCT/JP2012/078906 WO2013065869A1 (en) 2011-11-02 2012-11-01 Method for secretory production of protein

Publications (2)

Publication Number Publication Date
KR20140088215A KR20140088215A (ko) 2014-07-09
KR101653555B1 true KR101653555B1 (ko) 2016-09-02

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KR1020147015040A Active KR101653555B1 (ko) 2011-11-02 2012-11-01 단백질의 분비 생산 방법

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Country Link
US (1) US9187554B2 (enExample)
EP (1) EP2748340B1 (enExample)
JP (1) JP6020581B2 (enExample)
KR (1) KR101653555B1 (enExample)
CN (1) CN103946371B (enExample)
AU (1) AU2012333451B2 (enExample)
IN (1) IN2014CN04039A (enExample)
WO (1) WO2013065869A1 (enExample)

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IN2014CN04039A (enExample) 2011-11-02 2015-10-23 Ajinomoto Kk
CN103946372B (zh) 2011-11-02 2016-06-08 味之素株式会社 用于分泌产生蛋白质的方法
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
WO2015060391A1 (ja) 2013-10-23 2015-04-30 味の素株式会社 目的物質の製造法
EP3138907B1 (en) 2014-05-02 2020-02-26 Shinshu University Antibody gene expression-secretion system
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EP3287523B1 (en) 2015-04-24 2022-06-29 Ajinomoto Co., Inc. Method for secretory production of protein
CN109937258B (zh) * 2016-10-21 2023-06-23 味之素株式会社 蛋白质的分泌产生方法
AU2017347016B2 (en) 2016-10-21 2021-09-23 Ajinomoto Co., Inc. Secretory production method for protein
WO2018179834A1 (en) 2017-03-28 2018-10-04 Ajinomoto Co., Inc. Method for producing rna
BR112020016770A2 (pt) 2018-02-20 2020-12-15 Ajinomoto Co., Inc. Método para induzir silenciamento de rna e para produzir uma composição para induzir silenciamento de rna em um organismo-alvo, e, composição para induzir silenciamento de rna em um organismo-alvo
EP3783106A4 (en) 2018-04-20 2022-01-05 Ajinomoto Co., Inc. PROCESS FOR THE SECRETION OF A PROTEIN
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN112930359A (zh) 2018-10-25 2021-06-08 味之素株式会社 蛋白质的分泌生产方法
CN111909879B (zh) * 2020-08-24 2023-04-28 江南大学 一种高效表达外源蛋白的谷氨酸棒杆菌诱变菌株及应用
CA3207134A1 (en) 2021-02-19 2022-08-25 Jeffrey A. Ledbetter Dnase fusion polypeptides and related compositions and methods
WO2023282315A1 (ja) 2021-07-07 2023-01-12 味の素株式会社 非天然アミノ酸含有タンパク質の分泌生産法
EP4509613A1 (en) 2022-04-15 2025-02-19 Ajinomoto Co., Inc. Method for producing cultured meat
WO2024172163A1 (ja) 2023-02-16 2024-08-22 味の素株式会社 タンパク質の分泌生産法

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CN102089437B (zh) 2008-07-09 2014-11-05 味之素株式会社 生产氨基羟基苯甲酸盐类化合物的方法
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CN103946372B (zh) 2011-11-02 2016-06-08 味之素株式会社 用于分泌产生蛋白质的方法

Also Published As

Publication number Publication date
CN103946371B (zh) 2016-07-06
JP6020581B2 (ja) 2016-11-02
EP2748340B1 (en) 2016-06-01
IN2014CN04039A (enExample) 2015-10-23
AU2012333451B2 (en) 2015-05-21
KR20140088215A (ko) 2014-07-09
JP2014532424A (ja) 2014-12-08
AU2012333451A1 (en) 2014-04-03
RU2014122201A (ru) 2015-12-10
US20140255996A1 (en) 2014-09-11
EP2748340A1 (en) 2014-07-02
CN103946371A (zh) 2014-07-23
WO2013065869A1 (en) 2013-05-10
US9187554B2 (en) 2015-11-17

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