KR101572701B1 - Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ'-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도 - Google Patents

Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ'-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도 Download PDF

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KR101572701B1
KR101572701B1 KR1020107008302A KR20107008302A KR101572701B1 KR 101572701 B1 KR101572701 B1 KR 101572701B1 KR 1020107008302 A KR1020107008302 A KR 1020107008302A KR 20107008302 A KR20107008302 A KR 20107008302A KR 101572701 B1 KR101572701 B1 KR 101572701B1
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compound
salt
certain embodiments
xrpd
hcl salt
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KR20100061734A (ko
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쉬리파드 바그와트
웨이 라이
스테판 디. 페어런트
멜라니 제이. 로우
앨런 슈워츠
발레리야 엔. 스몰렌스카야
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암비트 바이오사이언시즈 코포레이션
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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KR1020107008302A 2007-09-19 2008-09-19 Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ'-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도 Active KR101572701B1 (ko)

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US99463507P 2007-09-19 2007-09-19
US60/994,635 2007-09-19

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KR1020157023723A Division KR20150104231A (ko) 2007-09-19 2008-09-19 Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ''-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도

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KR20100061734A KR20100061734A (ko) 2010-06-08
KR101572701B1 true KR101572701B1 (ko) 2015-11-27

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KR1020107008302A Active KR101572701B1 (ko) 2007-09-19 2008-09-19 Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ'-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도
KR1020157023723A Ceased KR20150104231A (ko) 2007-09-19 2008-09-19 Ｎ-(5-ｔｅｒｔ-부틸-이속사졸-3-일)-Ｎ''-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-Ｂ][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도

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US (2) US8883783B2 (https=)
EP (1) EP2201018B1 (https=)
JP (1) JP5462168B2 (https=)
KR (2) KR101572701B1 (https=)
CN (1) CN101868465B (https=)
AR (1) AR068528A1 (https=)
AU (1) AU2008302744B2 (https=)
BR (1) BRPI0816904B8 (https=)
CA (1) CA2696776C (https=)
CY (1) CY1117583T1 (https=)
DK (1) DK2201018T3 (https=)
ES (1) ES2573292T3 (https=)
HR (1) HRP20160520T1 (https=)
HU (1) HUE027982T2 (https=)
IL (1) IL203926A (https=)
MX (1) MX2010002295A (https=)
PL (1) PL2201018T3 (https=)
SI (1) SI2201018T1 (https=)
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CA2696776C (en) 2007-09-19 2015-12-15 Ambit Biosciences Corporation Solid forms comprising n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith
CA2696807C (en) * 2007-11-08 2017-11-28 Ambit Biosciences Corp. Methods of administering n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea to treat proliferative disease
CN102438588B (zh) * 2009-03-23 2015-04-01 埃姆比特生物科学公司 使用联合治疗法治疗疾病的方法
SMT202000092T1 (it) 2009-05-14 2020-05-08 Ambit Biosciences Corp Formulazione essiccata a spruzzo o liofilizzata di ac220
CN104447801A (zh) * 2009-11-05 2015-03-25 埃姆比特生物科学公司 用于制备咪唑并[2,1-b][1,3]苯并噻唑衍生物的方法
WO2011056764A1 (en) 2009-11-05 2011-05-12 Ambit Biosciences Corp. Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
CN103172648B (zh) 2011-12-20 2016-05-25 上海迪诺医药科技有限公司 三杂环衍生物、制备方法及应用
JP6116847B2 (ja) 2012-10-01 2017-04-19 アムビト バイオサイエンシス コーポレーションＡｍｂｉｔ Ｂｉｏｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ シクロデキストリンとの混合体を含有する錠剤
CN104513258B (zh) * 2013-09-26 2018-04-03 广东东阳光药业有限公司 取代脲衍生物及其在药物中的应用
JP6564449B2 (ja) 2015-02-20 2019-08-21 第一三共株式会社 がんの併用治療法
ES2889749T3 (es) * 2017-07-13 2022-01-13 Sunshine Lake Pharma Co Ltd Sal de derivado de urea sustituido y uso de la misma en medicina
BR112020001172A2 (pt) * 2017-07-18 2020-07-28 Agrimetis, Llc métodos para purificar l-glufosinato
CN110763544A (zh) * 2019-09-20 2020-02-07 南京聚谱检测科技有限公司 一种激光剥蚀样品制靶用快干可精磨粘合剂
CN111413421A (zh) * 2020-02-20 2020-07-14 广东电科院能源技术有限责任公司 污泥燃烧后灰尘中氯离子含量的测试方法、控制方法

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