KR101463243B1 - 눈, 귀 및 코 치료용 항생제 조성물 - Google Patents

눈, 귀 및 코 치료용 항생제 조성물 Download PDF

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Publication number
KR101463243B1
KR101463243B1 KR1020017003377A KR20017003377A KR101463243B1 KR 101463243 B1 KR101463243 B1 KR 101463243B1 KR 1020017003377 A KR1020017003377 A KR 1020017003377A KR 20017003377 A KR20017003377 A KR 20017003377A KR 101463243 B1 KR101463243 B1 KR 101463243B1
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KR
South Korea
Prior art keywords
eye
ear
nose
delete delete
compositions
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Expired - Lifetime
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KR1020017003377A
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English (en)
Korean (ko)
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KR20010075138A (ko
Inventor
카글제랄드
아브시르로버트엘.
스트로만데이비드더블유.
야니존엠.
Original Assignee
알콘 래보레이토리스, 인코퍼레이티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101463243(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 알콘 래보레이토리스, 인코퍼레이티드 filed Critical 알콘 래보레이토리스, 인코퍼레이티드
Publication of KR20010075138A publication Critical patent/KR20010075138A/ko
Application granted granted Critical
Publication of KR101463243B1 publication Critical patent/KR101463243B1/ko
Assigned to 알콘 리서치, 리미티드 reassignment 알콘 리서치, 리미티드 권리의 전부이전등록 Assignors: 알콘 래보레이토리스, 인코퍼레이티드
Assigned to 알콘 파아마슈티칼스 리미티드 reassignment 알콘 파아마슈티칼스 리미티드 권리의 전부이전등록 Assignors: 알콘 리서치, 리미티드
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020017003377A 1998-09-30 1999-09-29 눈, 귀 및 코 치료용 항생제 조성물 Expired - Lifetime KR101463243B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10250698P 1998-09-30 1998-09-30
US10250498P 1998-09-30 1998-09-30
US60/102,504 1998-09-30
US60/102,506 1998-09-30

Publications (2)

Publication Number Publication Date
KR20010075138A KR20010075138A (ko) 2001-08-09
KR101463243B1 true KR101463243B1 (ko) 2014-12-17

Family

ID=26799441

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017003377A Expired - Lifetime KR101463243B1 (ko) 1998-09-30 1999-09-29 눈, 귀 및 코 치료용 항생제 조성물

Country Status (18)

Country Link
EP (5) EP2269602B1 (https=)
JP (5) JP2002525317A (https=)
KR (1) KR101463243B1 (https=)
CN (2) CN100374114C (https=)
AR (2) AR020661A1 (https=)
AT (2) ATE254458T1 (https=)
AU (1) AU762827B2 (https=)
BR (1) BRPI9914151B1 (https=)
CA (3) CA2774207A1 (https=)
CY (3) CY1111404T1 (https=)
DE (2) DE69912972T2 (https=)
DK (5) DK2796138T3 (https=)
ES (4) ES2602956T3 (https=)
HK (1) HK1038691B (https=)
PT (5) PT2796138T (https=)
TR (2) TR200704370T2 (https=)
TW (1) TWI222361B (https=)
WO (1) WO2000018386A2 (https=)

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US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
DE19937115A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
JP2003510263A (ja) 1999-09-24 2003-03-18 アルコン，インコーポレイテッド シプロフロキサシンおよびデキサメタゾンを含有する局所用懸濁処方物
DE19962470A1 (de) * 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
AU2001261748A1 (en) * 2000-05-19 2001-12-03 Alcon Laboratories Inc. Antibiotic compositions for treatment of the eye, ear and nose
CA2412575C (en) 2000-07-26 2009-12-29 Onkar N. Singh Improved process for manufacturing compositions containing ciprofloxacin and hydrocortisone
WO2002040028A1 (fr) * 2000-11-16 2002-05-23 Wakamoto Pharmaceutical Co., Ltd. Gouttes pour les yeux en gel antibacterien
AU2002226926A1 (en) * 2000-12-20 2002-07-01 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
WO2002049633A2 (en) 2000-12-20 2002-06-27 Alcon, Inc. Use of amidoamines to treat or prevent acanthamoeba and fungal infections
CN1231218C (zh) 2001-09-21 2005-12-14 爱尔康公司 药物组合物在制备用于治疗中耳感染的药物中的用途
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
WO2005026147A1 (ja) 2003-09-10 2005-03-24 Kyorin Pharmaceutical Co., Ltd. ７−（４−置換−３−シクロプロピルアミノメチル−１−ピロリジニル）キノロンカルボン酸誘導体
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
WO2006029074A2 (en) * 2004-09-03 2006-03-16 Piedmont Pharmaceuticals, Llc Methods for transmembrane treatment and prevention of otitis media
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
WO2006065301A2 (en) * 2004-12-10 2006-06-22 Alcon, Inc. Compositions for treatment of ear infections
CN101317847B (zh) * 2007-06-06 2010-10-13 深圳市瑞谷医药技术有限公司 一种眼用或耳鼻用药物组合物及其用途
TWI495469B (zh) * 2008-06-09 2015-08-11 Alcon Res Ltd 含有氟喹諾酮抗生素藥物之經改良藥學組成物
AU2010266120B2 (en) * 2009-07-02 2014-02-06 Curofin Pharma Gmbh Compositions comprising finafloxacin and methods for treating ophthalmic, otic, or nasal infections
RU2576029C2 (ru) * 2010-01-07 2016-02-27 Риджентс Оф Дзе Юниверсити Оф Миннесота Способы и композиции для нанесения моксифлоксацина в ухо
WO2013085769A1 (en) 2011-12-06 2013-06-13 Alcon Research, Ltd. Cellulosic gel composition with improved viscosity stability
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
US9504691B2 (en) 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
CN104224802B (zh) * 2014-09-19 2017-12-12 南京优科生物医药研究有限公司 一种盐酸莫西沙星滴耳剂及其制备方法
RU2595837C2 (ru) * 2014-09-29 2016-08-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазных капель
TWI713618B (zh) * 2015-10-29 2020-12-21 日商帝化製藥股份有限公司 外用劑
JP2021524861A (ja) * 2018-04-03 2021-09-16 ハイデラバード アイ リサーチ ファウンデーション フルオロキノロン系抗生物質の眼内投与のための粘膜付着性薬物送達システム
IT201900005280A1 (it) * 2019-04-05 2020-10-05 Ntc S R L Composizione otologica
WO2021252054A1 (en) * 2020-06-10 2021-12-16 Ocular Science, Inc. Compositions and uses in method for post-operative ocular care
CN116270662A (zh) * 2021-12-03 2023-06-23 苏州欧康维视生物科技有限公司 盐酸莫西沙星地塞米松磷酸钠滴眼液
KR102656260B1 (ko) 2022-10-14 2024-04-09 주식회사태준제약 목시플록사신을 포함하는 안과용 조성물

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WO1990001933A1 (en) * 1988-08-26 1990-03-08 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use

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ATE285221T1 (de) 1998-09-23 2005-01-15 Unilever Nv Orale zusammensetzung mit verbessertem bleichendem effekt
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
KR20010107754A (ko) * 2000-05-26 2001-12-07 민경윤 경구투여용 속용정의 제조 방법

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1990001933A1 (en) * 1988-08-26 1990-03-08 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use

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BRPI9914151B8 (https=) 2021-05-25
BRPI9914151B1 (pt) 2017-10-03
DK2301541T3 (da) 2014-09-01
ATE501732T1 (de) 2011-04-15
JP5563041B2 (ja) 2014-07-30
ES2519190T3 (es) 2014-11-06
DE69912972T2 (de) 2004-04-22
TR200704370T2 (tr) 2007-11-21
BR9914151A (pt) 2001-06-26
CA2342211C (en) 2009-05-26
DK1384478T3 (da) 2011-05-23
JP2013018799A (ja) 2013-01-31
CA2774207A1 (en) 2000-04-06
DE69943287D1 (de) 2011-04-28
EP1384478B1 (en) 2011-03-16
JP2009007375A (ja) 2009-01-15
HK1150756A1 (en) 2012-01-13
EP2796138B1 (en) 2016-08-17
CN100374114C (zh) 2008-03-12
EP2796138A1 (en) 2014-10-29
EP2301541A1 (en) 2011-03-30
EP2301541B1 (en) 2014-08-20
WO2000018386A2 (en) 2000-04-06
ES2602956T3 (es) 2017-02-23
HK1059572A1 (en) 2004-07-09
CY1111404T1 (el) 2015-08-05
AR020661A1 (es) 2002-05-22
AU1310100A (en) 2000-04-17
DK2796138T3 (en) 2016-12-05
EP2269602B1 (en) 2014-11-19
JP2002525317A (ja) 2002-08-13
ES2207307T3 (es) 2004-05-16
DK2269602T3 (en) 2014-12-15
PT1117401E (pt) 2004-03-31
PT2269602E (pt) 2014-12-29
CA2342211A1 (en) 2000-04-06
CA2659064A1 (en) 2000-04-06
AR081393A2 (es) 2012-08-29
HK1038691B (en) 2004-04-23
EP1384478A1 (en) 2004-01-28
DE69912972D1 (de) 2003-12-24
CN1184968C (zh) 2005-01-19
DK1117401T3 (da) 2004-02-23
AU762827B2 (en) 2003-07-03
JP2014144982A (ja) 2014-08-14
PT2796138T (pt) 2016-09-22
TWI222361B (en) 2004-10-21
HK1038691A1 (en) 2002-03-28
EP2269602A1 (en) 2011-01-05
EP1117401B1 (en) 2003-11-19
WO2000018386A3 (en) 2000-06-08
ES2526521T3 (es) 2015-01-13
CN1650863A (zh) 2005-08-10
CN1320035A (zh) 2001-10-31
ATE254458T1 (de) 2003-12-15
TR200100883T2 (tr) 2001-10-22
CY1115759T1 (el) 2017-01-25
EP1117401A2 (en) 2001-07-25
KR20010075138A (ko) 2001-08-09
HK1150769A1 (en) 2012-01-13
CY1115916T1 (el) 2017-01-25
PT2301541E (pt) 2014-10-29
PT1384478E (pt) 2011-05-12
JP2012067141A (ja) 2012-04-05

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