KR101454041B1 - 안구 장치 및 그의 제조 및 사용 방법 - Google Patents

안구 장치 및 그의 제조 및 사용 방법 Download PDF

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Publication number
KR101454041B1
KR101454041B1 KR1020097009197A KR20097009197A KR101454041B1 KR 101454041 B1 KR101454041 B1 KR 101454041B1 KR 1020097009197 A KR1020097009197 A KR 1020097009197A KR 20097009197 A KR20097009197 A KR 20097009197A KR 101454041 B1 KR101454041 B1 KR 101454041B1
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KR
South Korea
Prior art keywords
bioactive agent
matrix
delete delete
contact lens
agent
Prior art date
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Expired - Fee Related
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KR1020097009197A
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English (en)
Korean (ko)
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KR20090083901A (ko
Inventor
존 달라스 프루트
린 쿡 윈터톤
존 마틴 랠리
Original Assignee
노파르티스 아게
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Publication of KR20090083901A publication Critical patent/KR20090083901A/ko
Application granted granted Critical
Publication of KR101454041B1 publication Critical patent/KR101454041B1/ko
Assigned to 알콘 인코포레이티드 reassignment 알콘 인코포레이티드 권리의 전부이전등록 Assignors: 노파르티스 아게
Expired - Fee Related legal-status Critical Current
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts or implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/02Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04Contact lenses for the eyes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020097009197A 2006-11-06 2007-11-05 안구 장치 및 그의 제조 및 사용 방법 Expired - Fee Related KR101454041B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86442806P 2006-11-06 2006-11-06
US60/864,428 2006-11-06
PCT/US2007/023239 WO2008073193A2 (en) 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof

Publications (2)

Publication Number Publication Date
KR20090083901A KR20090083901A (ko) 2009-08-04
KR101454041B1 true KR101454041B1 (ko) 2014-10-27

Family

ID=39284102

Family Applications (1)

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KR1020097009197A Expired - Fee Related KR101454041B1 (ko) 2006-11-06 2007-11-05 안구 장치 및 그의 제조 및 사용 방법

Country Status (15)

Country Link
US (1) US20080124376A1 (https=)
EP (1) EP2094235A2 (https=)
JP (1) JP5586956B2 (https=)
KR (1) KR101454041B1 (https=)
CN (1) CN101534793A (https=)
AR (1) AR063561A1 (https=)
AU (1) AU2007332930B2 (https=)
BR (1) BRPI0718543A2 (https=)
CA (2) CA2668576C (https=)
MX (1) MX2009004365A (https=)
NO (1) NO20092101L (https=)
RU (1) RU2450802C2 (https=)
TW (1) TWI476022B (https=)
WO (1) WO2008073193A2 (https=)
ZA (1) ZA200901842B (https=)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
JP5591226B2 (ja) 2008-05-12 2014-09-17 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 眼内薬物送達装置および関連する方法
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
US8357760B2 (en) 2008-07-21 2013-01-22 Novartis Ag Silicone hydrogel contact lenses with convertible comfort agents
TWI531362B (zh) 2008-07-21 2016-05-01 艾爾康股份有限公司 具有治療劑遞送能力之眼科裝置
KR20110040969A (ko) 2008-08-05 2011-04-20 바이오미메디카, 인코포레이티드 폴리우레탄-그라프트된 하이드로겔
TWI506333B (zh) * 2008-12-05 2015-11-01 Novartis Ag 用以傳遞疏水性舒適劑之眼用裝置及其製造方法
US8409606B2 (en) 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
JP5247597B2 (ja) * 2009-06-03 2013-07-24 株式会社シード 湿潤性ハイドロゲルコンタクトレンズ及びその製造方法
US9522980B2 (en) 2010-05-06 2016-12-20 Johnson & Johnson Vision Care, Inc. Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same
ES2423914T3 (es) 2010-07-30 2013-09-25 Novartis Ag Lentes de hidrogel de silicona con superficies ricas en agua
CA2808528A1 (en) 2010-08-27 2012-03-01 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
US20130203813A1 (en) 2011-05-04 2013-08-08 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
US9170349B2 (en) 2011-05-04 2015-10-27 Johnson & Johnson Vision Care, Inc. Medical devices having homogeneous charge density and methods for making same
JP5990579B2 (ja) 2011-06-09 2016-09-14 ノバルティス アーゲー ナノテクスチャー表面を持つシリコーンヒドロゲルレンズ
KR102220710B1 (ko) * 2011-07-20 2021-03-02 브라이엄 영 유니버시티 소수성 세라게닌 화합물 및 이를 포함하는 기구
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
WO2013052105A2 (en) 2011-10-03 2013-04-11 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
CA2856512A1 (en) 2011-11-21 2013-05-30 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
WO2013165574A2 (en) 2012-05-02 2013-11-07 Brigham Young University Ceragenin particulate materials and methods for making same
US9297929B2 (en) 2012-05-25 2016-03-29 Johnson & Johnson Vision Care, Inc. Contact lenses comprising water soluble N-(2 hydroxyalkyl) (meth)acrylamide polymers or copolymers
US9244196B2 (en) 2012-05-25 2016-01-26 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
US10073192B2 (en) 2012-05-25 2018-09-11 Johnson & Johnson Vision Care, Inc. Polymers and nanogel materials and methods for making and using the same
WO2014038004A1 (ja) * 2012-09-05 2014-03-13 株式会社メニコン 薬物徐放性眼用レンズ及びその製造方法
CN104871036B (zh) 2012-12-17 2019-12-10 诺华股份有限公司 制备改进的uv吸收性眼用透镜的方法
US9161598B2 (en) 2012-12-21 2015-10-20 Coopervision International Holding Company, Lp Ophthalmic devices for delivery of beneficial agents
US9248928B2 (en) 2012-12-21 2016-02-02 Coopervision International Holding Company, Lp Methods of manufacturing contact lenses for delivery of beneficial agents
US9498035B2 (en) 2012-12-21 2016-11-22 Coopervision International Holding Company, Lp Silicone hydrogel contact lenses for sustained release of beneficial polymers
US9943529B2 (en) 2013-01-07 2018-04-17 Brigham Young University Methods for reducing cellular proliferation and treating certain diseases
SG2013091087A (en) * 2013-01-09 2014-08-28 Johnson & Johnson Vision Care Multi-piece insert device with glue seal for ophthalmic devices
RU2687275C2 (ru) * 2013-02-01 2019-05-13 Аллерган, Инк. Слезозаменитель, содержащий гиалуронат натрия и карбоксиметилцеллюлозу
WO2014151411A1 (en) 2013-03-15 2014-09-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US9591850B2 (en) * 2013-09-27 2017-03-14 Novartis Ag Compositions and methods for disinfecting and cleaning contact lenses
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
HUE038809T2 (hu) 2013-12-17 2018-11-28 Novartis Ag Térhálósított hidrofíl bevonattal ellátott szilikon hidrogél lencse
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
EP3186070B1 (en) 2014-08-26 2019-09-25 Novartis AG Method for applying stable coating on silicone hydrogel contact lenses
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
US10370403B2 (en) 2015-04-22 2019-08-06 Brigham Young University Methods for the synthesis of ceragenins
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
KR102604468B1 (ko) 2015-12-15 2023-11-22 알콘 인코포레이티드 실리콘 하이드로겔 콘택트 렌즈 상에 안정한 코팅을 적용하기 위한 방법
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
US10830923B2 (en) 2017-12-13 2020-11-10 Alcon Inc. Method for producing MPS-compatible water gradient contact lenses
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
US12186328B2 (en) 2019-05-23 2025-01-07 Brigham Young University Use of CSA compounds to stimulate stem cells and hair growth
US12233177B2 (en) 2019-09-16 2025-02-25 Amgen Inc. Method for external sterilization of drug delivery device
US12393057B2 (en) * 2020-12-15 2025-08-19 Coopervision International Limited Oleic acid-releasing contact lens
US20240118559A1 (en) * 2022-09-27 2024-04-11 Coopervision International Limited Sustained release of oleic acid from contact lenses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004305313A (ja) * 2003-04-03 2004-11-04 Seed Co Ltd 薬物徐放性眼用レンズ
US20060100408A1 (en) * 2002-03-11 2006-05-11 Powell P M Method for forming contact lenses comprising therapeutic agents

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128305C (https=) * 1963-09-11
DE2839249A1 (de) * 1977-09-12 1979-03-22 Toray Industries Verfahren zur herstellung einer weichen kontaktlinse und ausgangsloesung zur durchfuehrung des verfahrens
US4444711A (en) * 1981-12-21 1984-04-24 Husky Injection Molding Systems Ltd. Method of operating a two-shot injection-molding machine
US4460534A (en) * 1982-09-07 1984-07-17 International Business Machines Corporation Two-shot injection molding
US4668506A (en) * 1985-08-16 1987-05-26 Bausch & Lomb Incorporated Sustained-release formulation containing and amino acid polymer
DE3880824T2 (de) * 1987-11-09 1993-10-14 Chiron Ophthalmics Inc Implantierung von protheseanordnungen.
EP0336986B1 (en) * 1988-04-09 1992-10-07 Hewlett-Packard GmbH Polyacrylamide gels
US4983702A (en) * 1988-09-28 1991-01-08 Ciba-Geigy Corporation Crosslinked siloxane-urethane polymer contact lens
JP3085480B2 (ja) * 1991-10-02 2000-09-11 セイコーエプソン株式会社 ホルモン徐放性コンタクトレンズ
TW272976B (https=) * 1993-08-06 1996-03-21 Ciba Geigy Ag
US5712356A (en) * 1993-11-26 1998-01-27 Ciba Vision Corporation Cross-linkable copolymers and hydrogels
CA2178620A1 (en) * 1993-12-08 1995-06-15 Lisa B. Jungherr Microsphere drug delivery system
US5894002A (en) * 1993-12-13 1999-04-13 Ciba Vision Corporation Process and apparatus for the manufacture of a contact lens
US5843346A (en) * 1994-06-30 1998-12-01 Polymer Technology Corporation Method of cast molding contact lenses
US5760100B1 (en) * 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US5665840A (en) * 1994-11-18 1997-09-09 Novartis Corporation Polymeric networks from water-soluble prepolymers
TW349967B (en) * 1995-02-03 1999-01-11 Novartis Ag Process for producing contact lenses and a cross-linkable polyvinylalcohol used therefor
JP3785599B2 (ja) * 1995-02-03 2006-06-14 ノバルティス アクチエンゲゼルシャフト エステル又はアミド基を含む架橋ポリマー
US5583463A (en) * 1995-05-30 1996-12-10 Micron Technology, Inc. Redundant row fuse bank circuit
CN1234044A (zh) * 1996-10-21 1999-11-03 诺瓦提斯公司 可交联聚合物
TW425403B (en) * 1997-02-04 2001-03-11 Novartis Ag Branched polyurethane (meth)acrylate prepolymers, opthal-mic mouldings derived therefrom and processes for their manufacture
EP0961941B1 (en) * 1997-02-21 2002-04-17 Novartis AG Ophthalmic mouldings
US5981826A (en) * 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
US6011082A (en) * 1997-06-02 2000-01-04 Pharmacia & Upjohn Ab Process for the modification of elastomers with surface interpreting polymer networks and elastomers formed therefrom
AU9743298A (en) * 1997-09-16 1999-04-05 Novartis Ag Crosslinkable polyurea polymers
TW429327B (en) * 1997-10-21 2001-04-11 Novartis Ag Single mould alignment
US6039913A (en) * 1998-08-27 2000-03-21 Novartis Ag Process for the manufacture of an ophthalmic molding
EP1002807A1 (en) * 1998-11-20 2000-05-24 Novartis AG Functionalized resin derived from polyallylamine
US6395756B2 (en) * 1999-12-23 2002-05-28 Novartis Ag Use of ophthalmic agent
US6733755B2 (en) * 2000-02-04 2004-05-11 Supratek Pharma, Inc. Ligand for vascular endothelial growth factor receptor
JP5242876B2 (ja) * 2000-03-24 2013-07-24 ノバルティス アーゲー 架橋結合性または重合性プレポリマー
AR030341A1 (es) * 2000-08-14 2003-08-20 Novartis Ag Articulos biomedicos moldeados
US6511960B2 (en) * 2001-01-05 2003-01-28 Alphamed Pharmaceuticals Corp Cromolyn for eye and ear infections
US20030020870A1 (en) * 2001-06-27 2003-01-30 Zms, Llc Biomedical molding materials from semi-solid precursors
WO2004016671A1 (en) * 2002-08-14 2004-02-26 Novartis Ag Radiation-curable prepolymers
US20040105880A1 (en) * 2002-11-21 2004-06-03 Turner Josephine Sara Interpenetrating polymer network
JP4937491B2 (ja) * 2003-04-03 2012-05-23 株式会社シード カチオン性高分子ゲル及びそれを用いた薬物徐放性高分子ゲル
WO2005015184A1 (en) * 2003-07-30 2005-02-17 Novartis Ag Reflection hologram sensor in contact lens
US7977430B2 (en) * 2003-11-25 2011-07-12 Novartis Ag Crosslinkable polyurea prepolymers
EP1817362B1 (en) * 2004-11-22 2010-09-22 Novartis AG Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers
GB0502790D0 (en) * 2005-02-10 2005-03-16 Univ London Pharmacy Solid dispersion of hydrophobic bioactive
US9804295B2 (en) * 2005-05-05 2017-10-31 Novartis Ag Ophthalmic devices for sustained delivery of active compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060100408A1 (en) * 2002-03-11 2006-05-11 Powell P M Method for forming contact lenses comprising therapeutic agents
JP2004305313A (ja) * 2003-04-03 2004-11-04 Seed Co Ltd 薬物徐放性眼用レンズ

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Publication number Publication date
CA2668576A1 (en) 2008-06-19
MX2009004365A (es) 2009-05-05
AU2007332930A1 (en) 2008-06-19
RU2450802C2 (ru) 2012-05-20
JP5586956B2 (ja) 2014-09-10
JP2010508902A (ja) 2010-03-25
TW200826985A (en) 2008-07-01
ZA200901842B (en) 2010-05-26
TWI476022B (zh) 2015-03-11
US20080124376A1 (en) 2008-05-29
BRPI0718543A2 (pt) 2013-11-12
CA2914805C (en) 2017-12-12
NO20092101L (no) 2009-06-05
KR20090083901A (ko) 2009-08-04
AU2007332930B2 (en) 2011-03-17
WO2008073193A2 (en) 2008-06-19
WO2008073193A3 (en) 2009-03-26
AR063561A1 (es) 2009-02-04
CA2914805A1 (en) 2008-06-19
EP2094235A2 (en) 2009-09-02
CN101534793A (zh) 2009-09-16
RU2009121444A (ru) 2010-12-20
CA2668576C (en) 2016-03-22

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