CN101534793A - 眼科器件及其制造和使用方法 - Google Patents

眼科器件及其制造和使用方法 Download PDF

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Publication number
CN101534793A
CN101534793A CNA2007800412616A CN200780041261A CN101534793A CN 101534793 A CN101534793 A CN 101534793A CN A2007800412616 A CNA2007800412616 A CN A2007800412616A CN 200780041261 A CN200780041261 A CN 200780041261A CN 101534793 A CN101534793 A CN 101534793A
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CN
China
Prior art keywords
prepolymer
matrix
bioactive agent
bioactivator
vinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800412616A
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English (en)
Chinese (zh)
Inventor
J·D·普鲁伊特
L·C·温特顿
J·M·拉利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CN101534793A publication Critical patent/CN101534793A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2007800412616A 2006-11-06 2007-11-05 眼科器件及其制造和使用方法 Pending CN101534793A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86442806P 2006-11-06 2006-11-06
US60/864,428 2006-11-06

Publications (1)

Publication Number Publication Date
CN101534793A true CN101534793A (zh) 2009-09-16

Family

ID=39284102

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800412616A Pending CN101534793A (zh) 2006-11-06 2007-11-05 眼科器件及其制造和使用方法

Country Status (15)

Country Link
US (1) US20080124376A1 (https=)
EP (1) EP2094235A2 (https=)
JP (1) JP5586956B2 (https=)
KR (1) KR101454041B1 (https=)
CN (1) CN101534793A (https=)
AR (1) AR063561A1 (https=)
AU (1) AU2007332930B2 (https=)
BR (1) BRPI0718543A2 (https=)
CA (2) CA2914805C (https=)
MX (1) MX2009004365A (https=)
NO (1) NO20092101L (https=)
RU (1) RU2450802C2 (https=)
TW (1) TWI476022B (https=)
WO (1) WO2008073193A2 (https=)
ZA (1) ZA200901842B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
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CN103038699A (zh) * 2010-07-30 2013-04-10 诺瓦提斯公司 具有交联亲水涂层的硅氧烷水凝胶透镜
CN115668002A (zh) * 2020-12-15 2023-01-31 库博光学国际有限公司 释放油酸的隐形眼镜

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US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
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Cited By (7)

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Publication number Priority date Publication date Assignee Title
CN103038699A (zh) * 2010-07-30 2013-04-10 诺瓦提斯公司 具有交联亲水涂层的硅氧烷水凝胶透镜
CN103038699B (zh) * 2010-07-30 2015-03-18 诺华股份有限公司 具有交联亲水涂层的硅氧烷水凝胶透镜
CN104678462A (zh) * 2010-07-30 2015-06-03 诺华股份有限公司 具有交联亲水涂层的硅氧烷水凝胶透镜
CN104678462B (zh) * 2010-07-30 2019-11-05 诺华股份有限公司 具有交联亲水涂层的硅氧烷水凝胶透镜
CN115668002A (zh) * 2020-12-15 2023-01-31 库博光学国际有限公司 释放油酸的隐形眼镜
CN115668002B (zh) * 2020-12-15 2023-09-15 库博光学国际有限公司 释放油酸的隐形眼镜
US12393057B2 (en) 2020-12-15 2025-08-19 Coopervision International Limited Oleic acid-releasing contact lens

Also Published As

Publication number Publication date
BRPI0718543A2 (pt) 2013-11-12
KR101454041B1 (ko) 2014-10-27
CA2914805A1 (en) 2008-06-19
AU2007332930A1 (en) 2008-06-19
MX2009004365A (es) 2009-05-05
AR063561A1 (es) 2009-02-04
WO2008073193A2 (en) 2008-06-19
RU2450802C2 (ru) 2012-05-20
NO20092101L (no) 2009-06-05
ZA200901842B (en) 2010-05-26
CA2668576A1 (en) 2008-06-19
KR20090083901A (ko) 2009-08-04
AU2007332930B2 (en) 2011-03-17
RU2009121444A (ru) 2010-12-20
EP2094235A2 (en) 2009-09-02
CA2668576C (en) 2016-03-22
US20080124376A1 (en) 2008-05-29
WO2008073193A3 (en) 2009-03-26
CA2914805C (en) 2017-12-12
JP5586956B2 (ja) 2014-09-10
JP2010508902A (ja) 2010-03-25
TWI476022B (zh) 2015-03-11
TW200826985A (en) 2008-07-01

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