CA2668576C - Ocular devices and methods of making and using thereof - Google Patents

Ocular devices and methods of making and using thereof Download PDF

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Publication number
CA2668576C
CA2668576C CA2668576A CA2668576A CA2668576C CA 2668576 C CA2668576 C CA 2668576C CA 2668576 A CA2668576 A CA 2668576A CA 2668576 A CA2668576 A CA 2668576A CA 2668576 C CA2668576 C CA 2668576C
Authority
CA
Canada
Prior art keywords
bioactive agent
matrix
contact lens
forming material
polymeric matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2668576A
Other languages
English (en)
French (fr)
Other versions
CA2668576A1 (en
Inventor
John Dallas Pruitt
Lynn Cook Winterton
John Martin Lally
Original Assignee
Novartis AG
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG, Alcon Inc filed Critical Novartis AG
Priority to CA2914805A priority Critical patent/CA2914805C/en
Publication of CA2668576A1 publication Critical patent/CA2668576A1/en
Application granted granted Critical
Publication of CA2668576C publication Critical patent/CA2668576C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2668576A 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof Expired - Fee Related CA2668576C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2914805A CA2914805C (en) 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86442806P 2006-11-06 2006-11-06
US60/864,428 2006-11-06
PCT/US2007/023239 WO2008073193A2 (en) 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2914805A Division CA2914805C (en) 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof

Publications (2)

Publication Number Publication Date
CA2668576A1 CA2668576A1 (en) 2008-06-19
CA2668576C true CA2668576C (en) 2016-03-22

Family

ID=39284102

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2668576A Expired - Fee Related CA2668576C (en) 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof
CA2914805A Expired - Fee Related CA2914805C (en) 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2914805A Expired - Fee Related CA2914805C (en) 2006-11-06 2007-11-05 Ocular devices and methods of making and using thereof

Country Status (15)

Country Link
US (1) US20080124376A1 (https=)
EP (1) EP2094235A2 (https=)
JP (1) JP5586956B2 (https=)
KR (1) KR101454041B1 (https=)
CN (1) CN101534793A (https=)
AR (1) AR063561A1 (https=)
AU (1) AU2007332930B2 (https=)
BR (1) BRPI0718543A2 (https=)
CA (2) CA2668576C (https=)
MX (1) MX2009004365A (https=)
NO (1) NO20092101L (https=)
RU (1) RU2450802C2 (https=)
TW (1) TWI476022B (https=)
WO (1) WO2008073193A2 (https=)
ZA (1) ZA200901842B (https=)

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US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
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US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
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Also Published As

Publication number Publication date
CA2668576A1 (en) 2008-06-19
MX2009004365A (es) 2009-05-05
AU2007332930A1 (en) 2008-06-19
RU2450802C2 (ru) 2012-05-20
JP5586956B2 (ja) 2014-09-10
JP2010508902A (ja) 2010-03-25
TW200826985A (en) 2008-07-01
ZA200901842B (en) 2010-05-26
TWI476022B (zh) 2015-03-11
US20080124376A1 (en) 2008-05-29
BRPI0718543A2 (pt) 2013-11-12
CA2914805C (en) 2017-12-12
NO20092101L (no) 2009-06-05
KR20090083901A (ko) 2009-08-04
AU2007332930B2 (en) 2011-03-17
WO2008073193A2 (en) 2008-06-19
WO2008073193A3 (en) 2009-03-26
AR063561A1 (es) 2009-02-04
CA2914805A1 (en) 2008-06-19
EP2094235A2 (en) 2009-09-02
CN101534793A (zh) 2009-09-16
RU2009121444A (ru) 2010-12-20
KR101454041B1 (ko) 2014-10-27

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