KR101335841B1 - 호모세린 아세틸 트랜스퍼라제 활성을 가지는 변이형 폴리펩티드 및 이를 발현하는 미생물 - Google Patents
호모세린 아세틸 트랜스퍼라제 활성을 가지는 변이형 폴리펩티드 및 이를 발현하는 미생물 Download PDFInfo
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- KR101335841B1 KR101335841B1 KR1020110139228A KR20110139228A KR101335841B1 KR 101335841 B1 KR101335841 B1 KR 101335841B1 KR 1020110139228 A KR1020110139228 A KR 1020110139228A KR 20110139228 A KR20110139228 A KR 20110139228A KR 101335841 B1 KR101335841 B1 KR 101335841B1
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- homoserine
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- microorganism
- acetyl
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- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01031—Homoserine O-acetyltransferase (2.3.1.31)
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- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR112013015991-0A BR112013015991B1 (pt) | 2010-12-21 | 2011-12-21 | Polipeptídeo modificado que possui atividade de homosserina acetiltransferase, polinucleotídeo que codifica o referido polipeptídeo, vetor recombinante, microorganismo do gênero escherichia e método para a produção de o-acetil homosserina |
| NO11852010A NO2657250T3 (enExample) | 2010-12-21 | 2011-12-21 | |
| PCT/KR2011/009966 WO2012087039A2 (ko) | 2010-12-21 | 2011-12-21 | 호모세린 아세틸 트랜스퍼라제 활성을 가지는 변이형 폴리펩티드 및 이를 발현하는 미생물 |
| DK11852010.5T DK2657250T3 (en) | 2010-12-21 | 2011-12-21 | Polypeptide variant having homoserine acetyl transferase activity and microorganism expressing this |
| ES11852010.5T ES2650451T3 (es) | 2010-12-21 | 2011-12-21 | Variante de polipéptido que tiene actividad homoserina acetiltransferasa y microorganismo que expresa el mismo |
| RU2013133626/10A RU2557411C2 (ru) | 2010-12-21 | 2011-12-21 | Модифицированный полипептид, обдадающий гомосеринацетилтрансферазной активностью, и экспрессирующий его микроорганизм |
| CN201180065592.XA CN103797027B (zh) | 2010-12-21 | 2011-12-21 | 具有高丝氨酸乙酰转移酶活性的修饰多肽和表达其的微生物 |
| US13/996,990 US9127257B2 (en) | 2010-12-21 | 2011-12-21 | Modified polypeptide having homoserine acetyltransferase activity and microorganism expressing the same |
| JP2013546021A JP5758499B2 (ja) | 2010-12-21 | 2011-12-21 | ホモセリンアセチルトランスフェラーゼ活性を有する変異型ポリペプチド及びそれを発現する微生物 |
| MYPI2013002375A MY173933A (en) | 2010-12-21 | 2011-12-21 | Modified polypeptide having homoserine acetyltransferase activity and microorganism expressing the same |
| PL11852010T PL2657250T3 (pl) | 2010-12-21 | 2011-12-21 | Odmiana polipeptydu posiadającego aktywność acetylotransferazy homoseryny oraz mikroorganizm wyrażający to samo |
| EP11852010.5A EP2657250B1 (en) | 2010-12-21 | 2011-12-21 | Variant polypeptide having homoserine acetyltransferase activity and microorganism expressing same |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20100131953 | 2010-12-21 | ||
| KR1020100131953 | 2010-12-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20120070531A KR20120070531A (ko) | 2012-06-29 |
| KR101335841B1 true KR101335841B1 (ko) | 2013-12-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020110139228A Active KR101335841B1 (ko) | 2010-12-21 | 2011-12-21 | 호모세린 아세틸 트랜스퍼라제 활성을 가지는 변이형 폴리펩티드 및 이를 발현하는 미생물 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9127257B2 (enExample) |
| EP (1) | EP2657250B1 (enExample) |
| JP (1) | JP5758499B2 (enExample) |
| KR (1) | KR101335841B1 (enExample) |
| CN (1) | CN103797027B (enExample) |
| DK (1) | DK2657250T3 (enExample) |
| ES (1) | ES2650451T3 (enExample) |
| MY (1) | MY173933A (enExample) |
| NO (1) | NO2657250T3 (enExample) |
| PL (1) | PL2657250T3 (enExample) |
| RU (1) | RU2557411C2 (enExample) |
| WO (1) | WO2012087039A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10400256B2 (en) | 2015-06-04 | 2019-09-03 | Cj Cheiljedang Corporation | Polypeptide having the activity of exporting O-acetyl-homoserine |
| US10501763B2 (en) | 2014-06-05 | 2019-12-10 | Cj Cheiljedang Corporation | Microorganism producing O-acetyl-homoserine and method for producing O-acetylhomoserine using the same |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012135651A1 (en) | 2011-03-31 | 2012-10-04 | The Procter & Gamble Company | Systems, models and methods for identifying and evaluating skin-active agents effective for treating dandruff/seborrheic dermatitis |
| US9920357B2 (en) | 2012-06-06 | 2018-03-20 | The Procter & Gamble Company | Systems and methods for identifying cosmetic agents for hair/scalp care compositions |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2012087039A2 (ko) | 2012-06-28 |
| ES2650451T3 (es) | 2018-01-18 |
| JP5758499B2 (ja) | 2015-08-05 |
| DK2657250T3 (en) | 2017-12-11 |
| MY173933A (en) | 2020-02-27 |
| EP2657250A2 (en) | 2013-10-30 |
| EP2657250B1 (en) | 2017-09-06 |
| KR20120070531A (ko) | 2012-06-29 |
| BR112013015991A2 (pt) | 2018-07-10 |
| RU2013133626A (ru) | 2015-01-27 |
| CN103797027B (zh) | 2017-05-17 |
| JP2014502843A (ja) | 2014-02-06 |
| CN103797027A (zh) | 2014-05-14 |
| US9127257B2 (en) | 2015-09-08 |
| NO2657250T3 (enExample) | 2018-02-03 |
| RU2557411C2 (ru) | 2015-07-20 |
| US20130273615A1 (en) | 2013-10-17 |
| WO2012087039A3 (ko) | 2012-08-23 |
| PL2657250T3 (pl) | 2018-02-28 |
| EP2657250A4 (en) | 2015-02-18 |
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