SG11201913889WA - Novel o-succinyl homoserine transferase variant and method of producing o-succinyl homoserine using the same - Google Patents

Novel o-succinyl homoserine transferase variant and method of producing o-succinyl homoserine using the same

Info

Publication number
SG11201913889WA
SG11201913889WA SG11201913889WA SG11201913889WA SG11201913889WA SG 11201913889W A SG11201913889W A SG 11201913889WA SG 11201913889W A SG11201913889W A SG 11201913889WA SG 11201913889W A SG11201913889W A SG 11201913889WA SG 11201913889W A SG11201913889W A SG 11201913889WA
Authority
SG
Singapore
Prior art keywords
succinyl homoserine
novel
producing
same
transferase variant
Prior art date
Application number
SG11201913889WA
Inventor
Kyungrim Kim
Jihyun Shim
Hyun Ah Kim
Yong Uk Shin
Peter Lee
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of SG11201913889WA publication Critical patent/SG11201913889WA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/08Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols by replacement of hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02004Aspartate kinase (2.7.2.4)
SG11201913889WA 2017-06-30 2018-06-29 Novel o-succinyl homoserine transferase variant and method of producing o-succinyl homoserine using the same SG11201913889WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20170083438 2017-06-30
PCT/KR2018/007408 WO2019004779A2 (en) 2017-06-30 2018-06-29 Novel o-succinyl homoserine transferase mutant and method for producing o-succinyl homoserine using same

Publications (1)

Publication Number Publication Date
SG11201913889WA true SG11201913889WA (en) 2020-01-30

Family

ID=64741762

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201913889WA SG11201913889WA (en) 2017-06-30 2018-06-29 Novel o-succinyl homoserine transferase variant and method of producing o-succinyl homoserine using the same

Country Status (9)

Country Link
US (1) US11142779B2 (en)
EP (1) EP3647416A4 (en)
JP (1) JP6980819B2 (en)
KR (1) KR102112232B1 (en)
CN (1) CN111315877B (en)
BR (1) BR112019027949A2 (en)
RU (1) RU2747493C1 (en)
SG (1) SG11201913889WA (en)
WO (1) WO2019004779A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016036209A1 (en) * 2014-09-05 2016-03-10 씨제이제일제당 주식회사 Microorganism with improved l-threonine productivity, and method for producing l-threonine by using same
CA3040585A1 (en) 2016-10-27 2018-05-03 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthases
CN112063572B (en) * 2020-09-22 2022-07-19 浙江工业大学 Recombinant escherichia coli capable of highly producing O-acetyl-L-homoserine and application thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK18862001A3 (en) 1999-06-25 2002-11-06 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding metabolic pathway proteins
KR100620092B1 (en) 2004-12-16 2006-09-08 씨제이 주식회사 Novel promoter nucleic acid derived from corynebacterium genus bacteria expression cassette comprising the promoter and vector comprising the cassette host cell comprising the vector and method for expressing a gene using the cell
KR100905381B1 (en) * 2006-07-28 2009-06-30 씨제이제일제당 (주) Microorganism producing l-methionine precursor and method of producing l-methionine and organic acid from the l-methionine precurosr
WO2008033001A1 (en) 2006-09-15 2008-03-20 Cj Cheiljedang Corporation A corynebacteria having enhanced l-lysine productivity and a method of producing l-lysine using the same
KR100930203B1 (en) 2008-01-28 2009-12-07 씨제이제일제당 (주) Improved promoter and method for producing L-lysine using the same
KR101048593B1 (en) 2009-02-27 2011-07-12 씨제이제일제당 (주) How to increase methionine production using a mixture of methylmercaptan and dimethylsulfide
ES2650451T3 (en) * 2010-12-21 2018-01-18 Cj Cheiljedang Corporation Polypeptide variant that has homoserine acetyltransferase activity and microorganism that expresses the same
KR101565213B1 (en) * 2013-10-23 2015-11-03 씨제이제일제당 (주) Microorganisms for production of o-succinyl homoserine and method for production of o-succinyl homoserine using the same
RU2017142360A (en) * 2015-05-06 2019-06-06 Трелис, Инк. COMPOSITIONS AND METHODS FOR BIOLOGICAL OBTAINING OF METHIONINE

Also Published As

Publication number Publication date
KR20190003401A (en) 2019-01-09
RU2747493C1 (en) 2021-05-05
EP3647416A4 (en) 2021-03-03
CN111315877A (en) 2020-06-19
CN111315877B (en) 2023-08-08
US11142779B2 (en) 2021-10-12
WO2019004779A3 (en) 2019-05-02
WO2019004779A2 (en) 2019-01-03
US20200332322A1 (en) 2020-10-22
KR102112232B1 (en) 2020-05-19
EP3647416A2 (en) 2020-05-06
JP6980819B2 (en) 2021-12-15
BR112019027949A2 (en) 2020-07-21
JP2020525017A (en) 2020-08-27

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