KR101308527B1 - 비-이미다졸 알킬아민 히스타민 ｈ3-수용체 리간드를이용한 파킨슨씨병, 폐쇄수면무호흡증, 루이체치매, 혈관성치매의 치료 - Google Patents

비-이미다졸 알킬아민 히스타민 ｈ3-수용체 리간드를이용한 파킨슨씨병, 폐쇄수면무호흡증, 루이체치매, 혈관성치매의 치료 Download PDF

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KR101308527B1
KR101308527B1 KR1020077025126A KR20077025126A KR101308527B1 KR 101308527 B1 KR101308527 B1 KR 101308527B1 KR 1020077025126 A KR1020077025126 A KR 1020077025126A KR 20077025126 A KR20077025126 A KR 20077025126A KR 101308527 B1 KR101308527 B1 KR 101308527B1
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KR20080002904A (ko
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장-샤를 슈워츠
잔느-마리 르꽁뜨
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비오프로제
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020077025126A 2005-04-01 2006-03-30 비-이미다졸 알킬아민 히스타민 ｈ3-수용체 리간드를이용한 파킨슨씨병, 폐쇄수면무호흡증, 루이체치매, 혈관성치매의 치료 Expired - Lifetime KR101308527B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP05290727A EP1707203A1 (en) 2005-04-01 2005-04-01 Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands
EP05290727.6 2005-04-01
US66861805P 2005-04-06 2005-04-06
US60/668,618 2005-04-06
PCT/IB2006/000739 WO2006103546A2 (en) 2005-04-01 2006-03-30 Treatment of parkinson's disease, obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine h3-receptor ligands

Publications (2)

Publication Number Publication Date
KR20080002904A KR20080002904A (ko) 2008-01-04
KR101308527B1 true KR101308527B1 (ko) 2013-09-17

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KR1020077025126A Expired - Lifetime KR101308527B1 (ko) 2005-04-01 2006-03-30 비-이미다졸 알킬아민 히스타민 ｈ3-수용체 리간드를이용한 파킨슨씨병, 폐쇄수면무호흡증, 루이체치매, 혈관성치매의 치료

Country Status (27)

Country Link
US (1) US8486947B2 (https=)
EP (2) EP1707203A1 (https=)
JP (3) JP5546761B2 (https=)
KR (1) KR101308527B1 (https=)
CN (1) CN101171009B (https=)
AU (1) AU2006228413C1 (https=)
BR (1) BRPI0612216B1 (https=)
CA (1) CA2603656C (https=)
CY (1) CY1114636T1 (https=)
DK (1) DK1863487T4 (https=)
EA (1) EA016007B1 (https=)
ES (1) ES2426008T5 (https=)
HR (1) HRP20130748T4 (https=)
MA (1) MA29353B1 (https=)
ME (1) ME01713B (https=)
MX (1) MX2007012162A (https=)
NO (1) NO343603B1 (https=)
NZ (1) NZ561940A (https=)
PL (1) PL1863487T5 (https=)
PT (1) PT1863487E (https=)
RS (1) RS52911B2 (https=)
SG (1) SG147415A1 (https=)
SI (1) SI1863487T2 (https=)
TN (1) TNSN07365A1 (https=)
UA (1) UA94902C2 (https=)
WO (1) WO2006103546A2 (https=)
ZA (1) ZA200708086B (https=)

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US9108948B2 (en) 2006-06-23 2015-08-18 Abbvie Inc. Cyclopropyl amine derivatives
FR2903904A1 (fr) * 2006-07-21 2008-01-25 Bioprojet Soc Civ Ile Association de modafinil et d'un antagoniste ou agoniste inverse du recepteur h3
UA95644C2 (ru) 2006-07-25 2011-08-25 Сефалон, Инк. Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний
US8153813B2 (en) 2007-12-20 2012-04-10 Abbott Laboratories Benzothiazole and benzooxazole derivatives and methods of use
MX2010008375A (es) 2008-01-30 2011-03-04 Cephalon Inc Star Derivados de piperidina espirocíclicos substituidos como ligandos de receptores de histamina-3 (h3).
FR2932479A1 (fr) * 2008-06-13 2009-12-18 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
US8853390B2 (en) 2010-09-16 2014-10-07 Abbvie Inc. Processes for preparing 1,2-substituted cyclopropyl derivatives
US9181275B2 (en) 2011-08-11 2015-11-10 Abbvie Inc. Mercaptoamidine derivatives and methods of use
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
HK1207004A1 (zh) * 2012-10-05 2016-01-22 Vtv治疗有限责任公司 治療輕度和中度阿爾茨海默病的方法
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US11654283B2 (en) 2019-03-06 2023-05-23 Medtronic Xomed, Inc. Obstructive sleep apnea patient programmer for implantable devices
EP4248969A1 (en) 2022-03-23 2023-09-27 Bioprojet Use of pitolisant for treating severe fatigue
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US20020065278A1 (en) 2000-08-08 2002-05-30 Richard Apodaca Non-imidazole aryloxyalkylamines

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WO2001030346A1 (en) 1999-10-22 2001-05-03 The Victoria University Of Manchester Treatment of dyskinesia
US20020065278A1 (en) 2000-08-08 2002-05-30 Richard Apodaca Non-imidazole aryloxyalkylamines

Also Published As

Publication number Publication date
CN101171009B (zh) 2012-11-07
SI1863487T2 (sl) 2019-11-29
CY1114636T1 (el) 2016-10-05
EP1707203A1 (en) 2006-10-04
PL1863487T5 (pl) 2021-08-09
US8486947B2 (en) 2013-07-16
SI1863487T1 (sl) 2013-09-30
MX2007012162A (es) 2007-11-22
RS52911B2 (sr) 2019-11-29
CA2603656C (en) 2015-06-16
ES2426008T3 (es) 2013-10-18
MA29353B1 (fr) 2008-03-03
UA94902C2 (ru) 2011-06-25
DK1863487T4 (da) 2019-10-14
CN101171009A (zh) 2008-04-30
JP2014062126A (ja) 2014-04-10
DK1863487T3 (da) 2013-08-12
ME01713B (me) 2014-09-20
EP1863487B2 (en) 2019-07-17
BRPI0612216B1 (pt) 2022-04-19
US20090318433A1 (en) 2009-12-24
SG147415A1 (en) 2008-11-28
BRPI0612216A2 (pt) 2010-10-26
WO2006103546A2 (en) 2006-10-05
HRP20130748T4 (hr) 2019-11-15
PT1863487E (pt) 2013-08-29
NZ561940A (en) 2010-06-25
JP5955872B2 (ja) 2016-07-20
HRP20130748T1 (en) 2013-10-11
EA200702135A1 (ru) 2008-04-28
ES2426008T5 (es) 2020-03-20
AU2006228413C1 (en) 2012-02-02
RS52911B (sr) 2014-02-28
JP5546761B2 (ja) 2014-07-09
EP1863487A2 (en) 2007-12-12
AU2006228413B2 (en) 2011-09-15
PL1863487T3 (pl) 2014-10-31
WO2006103546A3 (en) 2007-03-01
AU2006228413A1 (en) 2006-10-05
EA016007B1 (ru) 2012-01-30
NO343603B1 (no) 2019-04-08
JP2016106142A (ja) 2016-06-16
CA2603656A1 (en) 2006-10-05
KR20080002904A (ko) 2008-01-04
JP2008534572A (ja) 2008-08-28
TNSN07365A1 (fr) 2008-12-31
NO20075086L (no) 2007-12-27
EP1863487B1 (en) 2013-05-29
ZA200708086B (en) 2008-10-29

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