ZA200708086B - Treatment of Parkinson's disease, obstructive sleep apnea, dementia with Lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3-receptor ligands - Google Patents
Treatment of Parkinson's disease, obstructive sleep apnea, dementia with Lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3-receptor ligandsInfo
- Publication number
- ZA200708086B ZA200708086B ZA200708086A ZA200708086A ZA200708086B ZA 200708086 B ZA200708086 B ZA 200708086B ZA 200708086 A ZA200708086 A ZA 200708086A ZA 200708086 A ZA200708086 A ZA 200708086A ZA 200708086 B ZA200708086 B ZA 200708086B
- Authority
- ZA
- South Africa
- Prior art keywords
- dementia
- parkinson
- disease
- treatment
- sleep apnea
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05290727A EP1707203A1 (en) | 2005-04-01 | 2005-04-01 | Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200708086B true ZA200708086B (en) | 2008-10-29 |
Family
ID=35169680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200708086A ZA200708086B (en) | 2005-04-01 | 2007-09-20 | Treatment of Parkinson's disease, obstructive sleep apnea, dementia with Lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3-receptor ligands |
Country Status (27)
Country | Link |
---|---|
US (1) | US8486947B2 (xx) |
EP (2) | EP1707203A1 (xx) |
JP (3) | JP5546761B2 (xx) |
KR (1) | KR101308527B1 (xx) |
CN (1) | CN101171009B (xx) |
AU (1) | AU2006228413C1 (xx) |
BR (1) | BRPI0612216B1 (xx) |
CA (1) | CA2603656C (xx) |
CY (1) | CY1114636T1 (xx) |
DK (1) | DK1863487T4 (xx) |
EA (1) | EA016007B1 (xx) |
ES (1) | ES2426008T5 (xx) |
HR (1) | HRP20130748T4 (xx) |
MA (1) | MA29353B1 (xx) |
ME (1) | ME01713B (xx) |
MX (1) | MX2007012162A (xx) |
NO (1) | NO343603B1 (xx) |
NZ (1) | NZ561940A (xx) |
PL (1) | PL1863487T5 (xx) |
PT (1) | PT1863487E (xx) |
RS (1) | RS52911B2 (xx) |
SG (1) | SG147415A1 (xx) |
SI (1) | SI1863487T2 (xx) |
TN (1) | TNSN07365A1 (xx) |
UA (1) | UA94902C2 (xx) |
WO (1) | WO2006103546A2 (xx) |
ZA (1) | ZA200708086B (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9108948B2 (en) | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
SG173312A1 (en) | 2006-06-23 | 2011-08-29 | Abbott Lab | Cyclopropyl amine derivatives as histamin h3 receptor modulators |
FR2903904A1 (fr) * | 2006-07-21 | 2008-01-25 | Bioprojet Soc Civ Ile | Association de modafinil et d'un antagoniste ou agoniste inverse du recepteur h3 |
BRPI0713836A2 (pt) | 2006-07-25 | 2013-05-28 | Cephalon Inc | composto, composiÇço farmacÊutica e mÉtodo para tratar distérbio |
US8153813B2 (en) | 2007-12-20 | 2012-04-10 | Abbott Laboratories | Benzothiazole and benzooxazole derivatives and methods of use |
EP2250176B1 (en) | 2008-01-30 | 2012-08-01 | Cephalon, Inc. | Substituted spirocyclic piperidine derivatives as histamine-3 (h3) receptor ligands |
FR2932479A1 (fr) * | 2008-06-13 | 2009-12-18 | Servier Lab | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
US9186353B2 (en) | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
WO2012037258A1 (en) | 2010-09-16 | 2012-03-22 | Abbott Laboratories | Processes for preparing 1,2-substituted cyclopropyl derivatives |
US9181275B2 (en) | 2011-08-11 | 2015-11-10 | Abbvie Inc. | Mercaptoamidine derivatives and methods of use |
WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
SG11201502210VA (en) * | 2012-10-05 | 2015-04-29 | Vtvx Holdings I Llc | Treatment of mild and moderate alzheimer's disease |
EP3391886A1 (en) | 2017-04-19 | 2018-10-24 | Novartis AG | The use of a h3r inverse agonist for the treatment of shift work disorder |
US20200281522A1 (en) | 2019-03-06 | 2020-09-10 | Medtronic Xomed, LLC | System and method for improved obstructive sleep apnea diagnostic for implantable devices |
EP4248969A1 (en) | 2022-03-23 | 2023-09-27 | Bioprojet | Use of pitolisant for treating severe fatigue |
Family Cites Families (38)
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JPS5815945A (ja) * | 1981-07-21 | 1983-01-29 | Teikoku Hormone Mfg Co Ltd | 新規なフエノキシアルキルアミン誘導体 |
FR2579596B1 (fr) | 1985-03-26 | 1987-11-20 | Inst Nat Sante Rech Med | (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique |
FR2671083B1 (fr) | 1990-12-31 | 1994-12-23 | Inst Nat Sante Rech Med | Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques. |
ES2108107T3 (es) | 1991-02-27 | 1997-12-16 | Seed Capital Investments | Derivados de imidazol que tienen actividad antagonista en el receptor h3 de histamina. |
IL104125A (en) | 1991-12-18 | 2000-08-31 | Schering Corp | Imidazolyl or imidazoylalkyl substituted with a four or five membered nitrogen containing heterocyclic ring and pharmaceutical compositions comprising them |
ES2089782T3 (es) | 1991-12-18 | 1996-10-01 | Schering Corp | Imidazolalquilo sustituido con un anillo heterociclico que contiene nitrogeno de seis elementos. |
FR2686084B1 (fr) | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
US5380858A (en) | 1992-04-01 | 1995-01-10 | The University Of Toledo | Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists |
US5639775A (en) | 1992-04-01 | 1997-06-17 | The University Of Toledo | 4-[4'-piperodinyl or 3'-pirrolidinyl] substituted imidazoles as H3 -receptor antagonists and therapeutic uses thereof |
US5486526A (en) * | 1992-04-01 | 1996-01-23 | The University Of Toledo | Histamine H3 -receptor antagonists and therapeutic uses thereof |
EP0680960A4 (en) | 1993-01-25 | 1997-05-14 | Green Cross Corp | IMIDAZOLE CONNECTION. |
JP3522790B2 (ja) | 1993-06-08 | 2004-04-26 | 花王株式会社 | H3−レセプター刺激薬 |
AU7823894A (en) | 1993-08-27 | 1995-03-21 | Vrije Universiteit | New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor |
GB9319534D0 (en) * | 1993-09-22 | 1993-11-10 | Boots Co Plc | Therapeutic agents |
AU693142B2 (en) | 1993-11-15 | 1998-06-25 | Schering Corporation | Phenyl-alkyl imidazoles as H3-receptor antagonists |
GB9411045D0 (en) * | 1994-06-02 | 1994-07-20 | Smithkline Beecham Plc | Compounds and use |
FR2732017B1 (fr) | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | Nouveaux derives de l'imidazole antagonistes et/ou agonistes du recepteur h3 de l'histamine, leur preparation et leurs applications therapeutiques |
US5652258A (en) | 1995-05-30 | 1997-07-29 | Gliatech, Inc. | 2-(4-imidazoyl) cyclopropyl derivatives |
CN1192144A (zh) | 1995-05-30 | 1998-09-02 | 格里亚特克公司 | 1h-4(5)-取代的咪唑衍生物 |
CA2222652A1 (en) | 1995-06-07 | 1996-12-19 | Gliatech, Inc. | 1h-4(5)-substituted imidazole derivatives |
AU709611B2 (en) | 1996-02-09 | 1999-09-02 | James Black Foundation Limited | Histamine h3 receptor ligands |
JP3925579B2 (ja) * | 1998-02-03 | 2007-06-06 | 日本精工株式会社 | 潤滑剤供給体、並びに前記潤滑剤供給体を備える転がり軸受、リニアガイド装置及びボールねじ装置 |
EP0982300A3 (en) | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
US6136559A (en) * | 1998-10-07 | 2000-10-24 | Ortho Pharmaceutical Corporation | DNA encoding as human histamine receptor of the H3 subtype |
PT1186594E (pt) * | 1999-06-11 | 2009-10-13 | Toyama Chemical Co Ltd | Derivados de n-alcoxialquil-n,n-dialquilamina ou os seus sais e medicamentos que os contêm para doenças de degeneração dos nervos |
GB9924941D0 (en) * | 1999-10-22 | 1999-12-22 | Univ Manchester | Treatment of dyskinesia |
US6620839B2 (en) * | 2000-07-13 | 2003-09-16 | Abbott Laboratories | 1,3-disubstituted and 1,3,3-trisubstituted pyrrolidines as histamine-3 receptor ligands and their therapeutic applications |
KR100819381B1 (ko) * | 2000-08-08 | 2008-04-04 | 오르토-맥네일 파마슈티칼, 인코퍼레이티드 | 비-이미다졸 아릴옥시알킬아민 |
EP1313470A4 (en) * | 2000-08-17 | 2005-02-16 | Gliatech Inc | NEW ALICYCLIC IMIDAZOLE AS H 3 ACTIVE SUBSTANCES |
EP1320364A1 (en) * | 2000-08-21 | 2003-06-25 | Gliatech, Inc. | The use of histamine h3-receptor inverse agonists for the control of appetite and treatment of obesity |
DE60224509T2 (de) * | 2001-03-29 | 2009-03-05 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Imidazolderivate verwendbar als histamin h3 rezeptorliganden |
WO2003044059A1 (en) * | 2001-11-15 | 2003-05-30 | Ortho-Mcneil Pharmaceutical, Inc. | Agonists of recombinant human histamine h3 receptor |
NZ533990A (en) * | 2001-12-10 | 2006-04-28 | Ortho Mcneil Pharm Inc | Phenylalkyne compounds useful for the treatment of disorders and conditions modulated by a histamine receptor |
EP1556046A1 (en) * | 2002-10-23 | 2005-07-27 | Janssen Pharmaceutica N.V. | Phenylpiperidines and phenylpyrrolidines as histamine h3 receptor modulators |
JP4735261B2 (ja) * | 2003-06-27 | 2011-07-27 | Msd株式会社 | ヘテロアリールオキシ含窒素飽和ヘテロ環誘導体 |
FR2856596B1 (fr) * | 2003-06-27 | 2007-04-27 | Bioprojet Soc Civ | Nouvelle association medicamenteuse psychiatrique et utilisation d'une antagoniste ou agoniste inverse du recepteur h3 de l'histamine pour preparer un medicament prevenant des effets indesirables de psychotropes. |
SE0302116D0 (sv) * | 2003-07-21 | 2003-07-21 | Astrazeneca Ab | Novel compounds |
JP4765627B2 (ja) * | 2003-09-22 | 2011-09-07 | Msd株式会社 | 新規ピペリジン誘導体 |
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2005
- 2005-04-01 EP EP05290727A patent/EP1707203A1/en not_active Withdrawn
-
2006
- 2006-03-29 AU AU2006228413A patent/AU2006228413C1/en active Active
- 2006-03-30 DK DK06744466.1T patent/DK1863487T4/da active
- 2006-03-30 CA CA2603656A patent/CA2603656C/en active Active
- 2006-03-30 EA EA200702135A patent/EA016007B1/ru not_active IP Right Cessation
- 2006-03-30 ME MEP-2013-98A patent/ME01713B/me unknown
- 2006-03-30 UA UAA200710712A patent/UA94902C2/ru unknown
- 2006-03-30 US US11/909,778 patent/US8486947B2/en active Active
- 2006-03-30 MX MX2007012162A patent/MX2007012162A/es active IP Right Grant
- 2006-03-30 WO PCT/IB2006/000739 patent/WO2006103546A2/en active Application Filing
- 2006-03-30 KR KR1020077025126A patent/KR101308527B1/ko active Protection Beyond IP Right Term
- 2006-03-30 CN CN2006800157656A patent/CN101171009B/zh active Active
- 2006-03-30 BR BRPI0612216-7A patent/BRPI0612216B1/pt active IP Right Grant
- 2006-03-30 PL PL06744466T patent/PL1863487T5/pl unknown
- 2006-03-30 SG SG200807447-8A patent/SG147415A1/en unknown
- 2006-03-30 ES ES06744466T patent/ES2426008T5/es active Active
- 2006-03-30 JP JP2008503613A patent/JP5546761B2/ja active Active
- 2006-03-30 RS RS20130359 patent/RS52911B2/sr unknown
- 2006-03-30 EP EP06744466.1A patent/EP1863487B2/en active Active
- 2006-03-30 NZ NZ561940A patent/NZ561940A/en unknown
- 2006-03-30 SI SI200631636T patent/SI1863487T2/sl unknown
- 2006-03-30 PT PT67444661T patent/PT1863487E/pt unknown
-
2007
- 2007-09-20 ZA ZA200708086A patent/ZA200708086B/xx unknown
- 2007-09-26 TN TNP2007000365A patent/TNSN07365A1/fr unknown
- 2007-09-27 MA MA30254A patent/MA29353B1/fr unknown
- 2007-10-09 NO NO20075086A patent/NO343603B1/no unknown
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2013
- 2013-08-07 HR HRP20130748T patent/HRP20130748T4/hr unknown
- 2013-08-14 CY CY20131100705T patent/CY1114636T1/el unknown
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2014
- 2014-01-06 JP JP2014000383A patent/JP5955872B2/ja active Active
-
2016
- 2016-03-09 JP JP2016045424A patent/JP2016106142A/ja active Pending
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