AU7823894A - New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor - Google Patents

New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor

Info

Publication number
AU7823894A
AU7823894A AU78238/94A AU7823894A AU7823894A AU 7823894 A AU7823894 A AU 7823894A AU 78238/94 A AU78238/94 A AU 78238/94A AU 7823894 A AU7823894 A AU 7823894A AU 7823894 A AU7823894 A AU 7823894A
Authority
AU
Australia
Prior art keywords
agonistic
histamine
receptor
antagonistic activity
imidazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU78238/94A
Inventor
Wiro Michael Petrus Bernardus Menge
Hendrik Timmerman
Roelant Christiaan Vollinga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vrije Universiteit Brussel VUB
Original Assignee
Vrije Universiteit Brussel VUB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL9302045A external-priority patent/NL9302045A/en
Application filed by Vrije Universiteit Brussel VUB filed Critical Vrije Universiteit Brussel VUB
Publication of AU7823894A publication Critical patent/AU7823894A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU78238/94A 1993-08-27 1994-08-29 New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor Abandoned AU7823894A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP93202528 1993-08-27
EP93202528 1993-08-27
NL9302045 1993-11-25
NL9302045A NL9302045A (en) 1993-08-27 1993-11-25 New imidazole derivative with agonistic or antagonistic activity on the histamine H3 receptor
PCT/NL1994/000206 WO1995006037A1 (en) 1993-08-27 1994-08-29 New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor

Publications (1)

Publication Number Publication Date
AU7823894A true AU7823894A (en) 1995-03-21

Family

ID=26133984

Family Applications (1)

Application Number Title Priority Date Filing Date
AU78238/94A Abandoned AU7823894A (en) 1993-08-27 1994-08-29 New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor

Country Status (2)

Country Link
AU (1) AU7823894A (en)
WO (1) WO1995006037A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732017B1 (en) * 1995-03-21 2000-09-22 Inst Nat Sante Rech Med NOVEL IMIDAZOLE DERIVATIVES AND / OR HISTAMINE H3 RECEPTOR AGONISTS AND / OR AGONISTS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATIONS
ATE242219T1 (en) * 1996-02-09 2003-06-15 Black James Foundation HISTAMINE H 3 RECEPTOR LIGANDS
GB9715816D0 (en) * 1997-07-25 1997-10-01 Black James Foundation Histamine H receptor ligands
US6407132B1 (en) * 1997-07-25 2002-06-18 James Black Foundation Limited Substituted imidazole derivatives and their use as histamine H3 receptor ligands
US5990147A (en) * 1997-11-07 1999-11-23 Schering Corporation H3 receptor ligands of the phenyl-alkyl-imidazoles type
US6034251A (en) * 1997-11-07 2000-03-07 Schering Corporation Phenyl-alkyl-imidazoles
WO1999024421A1 (en) * 1997-11-07 1999-05-20 Schering Corporation Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom
US6100279A (en) * 1998-11-05 2000-08-08 Schering Corporation Imidazoylalkyl substituted with a five, six or seven membered heterocyclic ring containing one nitrogen atom
AU3033100A (en) 1999-01-18 2000-08-01 Boehringer Ingelheim International Gmbh Substituted imidazoles, their preparation and use
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
US6610721B2 (en) 2000-03-17 2003-08-26 Novo Nordisk A/S Imidazo heterocyclic compounds
AU2001278821A1 (en) * 2000-08-21 2002-03-04 Pacific Corporation Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same
FR2827863A1 (en) * 2001-07-27 2003-01-31 Sanofi Synthelabo New dihydropyrrolyl alkyl imidazole derivatives having histamine receptor antagonist activity for treatment of obesity, diabetes, and central nervous system disorders
WO2003070722A1 (en) 2002-02-21 2003-08-28 Azwell Inc. Improvement in the production of imidazole derivatives and novel intermediates of the derivatives
EP1707203A1 (en) 2005-04-01 2006-10-04 Bioprojet Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands
EP1717233A1 (en) 2005-04-29 2006-11-02 Bioprojet Histamine H3-receptor ligands and their therapeutic application
EP1717235A3 (en) 2005-04-29 2007-02-28 Bioprojet Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
EP2076508B1 (en) 2006-10-18 2011-01-05 Pfizer Products Inc. Biaryl ether urea compounds
EP2348839B1 (en) * 2008-11-06 2017-04-05 MUSC Foundation For Research Development Lysosomotropic inhibitors of acid ceramidase
CA2788355C (en) 2010-02-18 2018-03-06 Devi Reddy Gohimukkula Phenyl-heteroaryl derivatives and methods of use thereof
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
WO2016100940A1 (en) 2014-12-19 2016-06-23 The Broad Institute, Inc. Dopamine d2 receptor ligands
US10752588B2 (en) 2014-12-19 2020-08-25 The Broad Institute, Inc. Dopamine D2 receptor ligands

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1305548A (en) * 1969-10-29 1973-02-07
CA938556A (en) * 1970-06-25 1973-12-18 Smith Kline And French Laboratories Limited Pharmaceutical compositions containing thiourea derivatives
FR2579596B1 (en) * 1985-03-26 1987-11-20 Inst Nat Sante Rech Med (IMIDAZOLYL-4) PIPERIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
DK0619818T3 (en) * 1991-12-18 1996-11-25 Schering Corp Imidazoylalkyl substituted with a six-membered nitrogen-containing heterocyclic ring

Also Published As

Publication number Publication date
WO1995006037A1 (en) 1995-03-02

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