DK1863487T4 - Behandling af symptomer på Parkinsons sygdom med alkylaminer uden imidazol som histamin H3-receptorligander - Google Patents

Behandling af symptomer på Parkinsons sygdom med alkylaminer uden imidazol som histamin H3-receptorligander Download PDF

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Publication number
DK1863487T4
DK1863487T4 DK06744466.1T DK06744466T DK1863487T4 DK 1863487 T4 DK1863487 T4 DK 1863487T4 DK 06744466 T DK06744466 T DK 06744466T DK 1863487 T4 DK1863487 T4 DK 1863487T4
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Prior art keywords
alkylamines
histamine
parkinson
imidazole
treatment
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DK06744466.1T
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Danish (da)
English (en)
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DK1863487T3 (da
Inventor
Jean-Charles Schwartz
Jeanne-Marie Lecomte
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Bioprojet Soc Civ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK06744466.1T 2005-04-01 2006-03-30 Behandling af symptomer på Parkinsons sygdom med alkylaminer uden imidazol som histamin H3-receptorligander DK1863487T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05290727A EP1707203A1 (en) 2005-04-01 2005-04-01 Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands
US66861805P 2005-04-06 2005-04-06
PCT/IB2006/000739 WO2006103546A2 (en) 2005-04-01 2006-03-30 Treatment of parkinson's disease, obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine h3-receptor ligands

Publications (2)

Publication Number Publication Date
DK1863487T3 DK1863487T3 (da) 2013-08-12
DK1863487T4 true DK1863487T4 (da) 2019-10-14

Family

ID=35169680

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06744466.1T DK1863487T4 (da) 2005-04-01 2006-03-30 Behandling af symptomer på Parkinsons sygdom med alkylaminer uden imidazol som histamin H3-receptorligander

Country Status (27)

Country Link
US (1) US8486947B2 (https=)
EP (2) EP1707203A1 (https=)
JP (3) JP5546761B2 (https=)
KR (1) KR101308527B1 (https=)
CN (1) CN101171009B (https=)
AU (1) AU2006228413C1 (https=)
BR (1) BRPI0612216B1 (https=)
CA (1) CA2603656C (https=)
CY (1) CY1114636T1 (https=)
DK (1) DK1863487T4 (https=)
EA (1) EA016007B1 (https=)
ES (1) ES2426008T5 (https=)
HR (1) HRP20130748T4 (https=)
MA (1) MA29353B1 (https=)
ME (1) ME01713B (https=)
MX (1) MX2007012162A (https=)
NO (1) NO343603B1 (https=)
NZ (1) NZ561940A (https=)
PL (1) PL1863487T5 (https=)
PT (1) PT1863487E (https=)
RS (1) RS52911B2 (https=)
SG (1) SG147415A1 (https=)
SI (1) SI1863487T2 (https=)
TN (1) TNSN07365A1 (https=)
UA (1) UA94902C2 (https=)
WO (1) WO2006103546A2 (https=)
ZA (1) ZA200708086B (https=)

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HRP20130044T1 (hr) 2006-07-25 2013-02-28 Cephalon, Inc. Derivati piridizinona
US8153813B2 (en) 2007-12-20 2012-04-10 Abbott Laboratories Benzothiazole and benzooxazole derivatives and methods of use
EP2250176B1 (en) 2008-01-30 2012-08-01 Cephalon, Inc. Substituted spirocyclic piperidine derivatives as histamine-3 (h3) receptor ligands
FR2932479A1 (fr) * 2008-06-13 2009-12-18 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
WO2012037258A1 (en) 2010-09-16 2012-03-22 Abbott Laboratories Processes for preparing 1,2-substituted cyclopropyl derivatives
US9181275B2 (en) 2011-08-11 2015-11-10 Abbvie Inc. Mercaptoamidine derivatives and methods of use
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds
NZ705813A (en) * 2012-10-05 2018-02-23 Vtv Therapeutics Llc Treatment of mild and moderate alzheimer’s disease
EP3391886A1 (en) 2017-04-19 2018-10-24 Novartis AG The use of a h3r inverse agonist for the treatment of shift work disorder
US20200282215A1 (en) 2019-03-06 2020-09-10 Medtronic Xomed, LLC Evaluating stimulation eficacy for treating sleep apnea and lingual muscle tone sensing system for improved osa therapy
EP4248969A1 (en) 2022-03-23 2023-09-27 Bioprojet Use of pitolisant for treating severe fatigue
EP4688166A1 (en) 2023-03-31 2026-02-11 BIOPROJET Pharma Polymorph form of pitolisant hydrochloride
WO2025082974A1 (en) 2023-10-16 2025-04-24 Bioprojet Pharma New formulations of pitolisant and methods of use

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Also Published As

Publication number Publication date
AU2006228413A1 (en) 2006-10-05
US8486947B2 (en) 2013-07-16
SI1863487T1 (sl) 2013-09-30
JP2008534572A (ja) 2008-08-28
ME01713B (me) 2014-09-20
CA2603656C (en) 2015-06-16
EP1707203A1 (en) 2006-10-04
JP2016106142A (ja) 2016-06-16
CA2603656A1 (en) 2006-10-05
RS52911B2 (sr) 2019-11-29
WO2006103546A2 (en) 2006-10-05
EP1863487B2 (en) 2019-07-17
ZA200708086B (en) 2008-10-29
EA200702135A1 (ru) 2008-04-28
BRPI0612216B1 (pt) 2022-04-19
AU2006228413B2 (en) 2011-09-15
MX2007012162A (es) 2007-11-22
HRP20130748T1 (en) 2013-10-11
JP2014062126A (ja) 2014-04-10
JP5955872B2 (ja) 2016-07-20
ES2426008T5 (es) 2020-03-20
EP1863487B1 (en) 2013-05-29
RS52911B (sr) 2014-02-28
KR101308527B1 (ko) 2013-09-17
NO343603B1 (no) 2019-04-08
BRPI0612216A2 (pt) 2010-10-26
AU2006228413C1 (en) 2012-02-02
SG147415A1 (en) 2008-11-28
EA016007B1 (ru) 2012-01-30
ES2426008T3 (es) 2013-10-18
DK1863487T3 (da) 2013-08-12
CN101171009A (zh) 2008-04-30
JP5546761B2 (ja) 2014-07-09
TNSN07365A1 (fr) 2008-12-31
CY1114636T1 (el) 2016-10-05
US20090318433A1 (en) 2009-12-24
SI1863487T2 (sl) 2019-11-29
PL1863487T3 (pl) 2014-10-31
HRP20130748T4 (hr) 2019-11-15
MA29353B1 (fr) 2008-03-03
WO2006103546A3 (en) 2007-03-01
EP1863487A2 (en) 2007-12-12
PL1863487T5 (pl) 2021-08-09
CN101171009B (zh) 2012-11-07
KR20080002904A (ko) 2008-01-04
UA94902C2 (ru) 2011-06-25
NZ561940A (en) 2010-06-25
PT1863487E (pt) 2013-08-29
NO20075086L (no) 2007-12-27

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