KR101162046B1 - ＩκＢ 키나제 조절용 인돌 또는 벤즈이미다졸 유도체 - Google Patents

ＩκＢ 키나제 조절용 인돌 또는 벤즈이미다졸 유도체 Download PDF

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KR101162046B1
KR101162046B1 KR1020057002707A KR20057002707A KR101162046B1 KR 101162046 B1 KR101162046 B1 KR 101162046B1 KR 1020057002707 A KR1020057002707 A KR 1020057002707A KR 20057002707 A KR20057002707 A KR 20057002707A KR 101162046 B1 KR101162046 B1 KR 101162046B1
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indole
ethyl
formula
compound
ylamino
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KR20050058338A (ko
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올라프 리트젤러
게르하르트 예네
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사노피-아벤티스 도이칠란트 게엠베하
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Neurology (AREA)
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  • Pain & Pain Management (AREA)
  • AIDS & HIV (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
KR1020057002707A 2002-08-17 2003-08-05 ＩκＢ 키나제 조절용 인돌 또는 벤즈이미다졸 유도체 Expired - Fee Related KR101162046B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10237722.7 2002-08-17
DE10237722A DE10237722A1 (de) 2002-08-17 2002-08-17 Indol- oder Benzimidazolderivate zur Modulation der IKappaB-Kinase
PCT/EP2003/008629 WO2004022553A1 (de) 2002-08-17 2003-08-05 INDOL-ODER BENZIMIDAZOLDERIVATE ZUR MODULATION DER IλB-KINASE

Publications (2)

Publication Number Publication Date
KR20050058338A KR20050058338A (ko) 2005-06-16
KR101162046B1 true KR101162046B1 (ko) 2012-07-04

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US (2) US7285560B2 (https=)
EP (2) EP2233483B1 (https=)
JP (1) JP4504812B2 (https=)
KR (1) KR101162046B1 (https=)
CN (1) CN1314683C (https=)
AR (1) AR040975A1 (https=)
AT (2) ATE493402T1 (https=)
AU (1) AU2003263196B2 (https=)
BR (1) BR0313562A (https=)
CA (1) CA2498559C (https=)
CO (1) CO5690586A2 (https=)
CR (1) CR7668A (https=)
CY (2) CY1111692T1 (https=)
DE (2) DE10237722A1 (https=)
DK (2) DK2233483T3 (https=)
EC (1) ECSP055612A (https=)
ES (2) ES2387954T3 (https=)
HN (1) HN2003000249A (https=)
HR (1) HRP20050042B1 (https=)
IL (1) IL166785A0 (https=)
JO (1) JO2764B1 (https=)
MA (1) MA27382A1 (https=)
ME (1) MEP60608A (https=)
MX (1) MXPA05001314A (https=)
MY (1) MY140074A (https=)
NO (1) NO330981B1 (https=)
NZ (1) NZ538296A (https=)
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PA (1) PA8580501A1 (https=)
PE (1) PE20040893A1 (https=)
PL (1) PL374229A1 (https=)
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RS (1) RS51902B (https=)
RU (1) RU2318820C2 (https=)
SI (2) SI1530568T1 (https=)
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Cited By (1)

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US9029334B2 (en) 2013-03-29 2015-05-12 Lifetree Biotech Co., Ltd. Pharmaceutical composition for prevention or treatment of bone diseases comprising spinasterol glucoside derivative

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DE10237722A1 (de) * 2002-08-17 2004-08-19 Aventis Pharma Deutschland Gmbh Indol- oder Benzimidazolderivate zur Modulation der IKappaB-Kinase
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AR050253A1 (es) 2004-06-24 2006-10-11 Smithkline Beecham Corp Compuesto derivado de indazol carboxamida, composicion que lo comprende y su uso para la preparacion de un medicamento
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BRPI0922435A2 (pt) 2008-12-19 2018-09-11 Sirtris Pharmaceuticals Inc "composto de tiazolopiridina moduladores de sirtuina, composição farmacêutica compreendendo o mesmo e seu uso."
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