KR101107911B1 - Ｕｇｔ1ａ1 유전자 증폭용 프라이머 셋트, 그것을 포함하는ｕｇｔ1ａ1 유전자 증폭용 시약 및 그 용도 - Google Patents

Ｕｇｔ1ａ1 유전자 증폭용 프라이머 셋트, 그것을 포함하는ｕｇｔ1ａ1 유전자 증폭용 시약 및 그 용도 Download PDF

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KR101107911B1
KR101107911B1 KR1020087020256A KR20087020256A KR101107911B1 KR 101107911 B1 KR101107911 B1 KR 101107911B1 KR 1020087020256 A KR1020087020256 A KR 1020087020256A KR 20087020256 A KR20087020256 A KR 20087020256A KR 101107911 B1 KR101107911 B1 KR 101107911B1
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oligonucleotide
base
seq
probe
primer
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KR20080101922A (ko
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미츠하루 히라이
사토시 마지마
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아크레이 가부시키가이샤
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Bioinformatics & Cheminformatics (AREA)
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  • Analytical Chemistry (AREA)
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  • Biomedical Technology (AREA)
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  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
KR1020087020256A 2006-11-30 2007-11-29 Ｕｇｔ1ａ1 유전자 증폭용 프라이머 셋트, 그것을 포함하는ｕｇｔ1ａ1 유전자 증폭용 시약 및 그 용도 Active KR101107911B1 (ko)

Applications Claiming Priority (5)

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JP2006322955 2006-11-30
JPJP-P-2006-00322955 2006-11-30
JPJP-P-2007-00232611 2007-09-07
JP2007232611 2007-09-07
PCT/JP2007/073107 WO2008066136A1 (en) 2006-11-30 2007-11-29 Primer set for amplification of ugt1a1 gene, reagent for amplification of ugt1a1 gene comprising the same, and use of the same

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KR1020117004014A Division KR101153058B1 (ko) 2006-11-30 2007-11-29 Ｕｇｔ1ａ1 유전자 증폭용 프라이머 셋트, 그것을 포함하는 ｕｇｔ1ａ1 유전자 증폭용 시약 및 그 용도

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KR101107911B1 true KR101107911B1 (ko) 2012-01-25

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KR1020087020256A Active KR101107911B1 (ko) 2006-11-30 2007-11-29 Ｕｇｔ1ａ1 유전자 증폭용 프라이머 셋트, 그것을 포함하는ｕｇｔ1ａ1 유전자 증폭용 시약 및 그 용도

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US (2) US8357516B2 (ja)
EP (2) EP2463365B1 (ja)
JP (1) JP5307538B2 (ja)
KR (2) KR101153058B1 (ja)
CN (3) CN102168141B (ja)
WO (1) WO2008066136A1 (ja)

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JP5637850B2 (ja) * 2008-07-02 2014-12-10 アークレイ株式会社 標的核酸配列の増幅方法、それを用いた変異の検出方法、および、それに用いる試薬
JP5661251B2 (ja) * 2009-03-31 2015-01-28 積水メディカル株式会社 Ｕｇｔ１ａ１遺伝子多型検出法
CN102471771B (zh) 2010-01-21 2016-01-20 爱科来株式会社 靶序列的扩增方法、多态性检测方法以及其中使用的试剂
JP2011250726A (ja) * 2010-06-01 2011-12-15 Toyo Kohan Co Ltd イリノテカンの副作用の発生危険度を判定する方法及びそのためのキット
US20120107815A1 (en) * 2010-10-28 2012-05-03 Arkray, Inc. Polymorphism Detection Probe, Polymorphism Detection Method, Evaluation of Drug Efficacy, and Polymorphism Detection Kit
JP5757908B2 (ja) * 2011-05-02 2015-08-05 アークレイ株式会社 多型検出用プローブ、多型検出方法、薬効評価方法、疾患予測方法及び多型検出用試薬キット
JP5757909B2 (ja) * 2011-05-02 2015-08-05 アークレイ株式会社 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用試薬キット
AU2013202947B2 (en) * 2012-06-13 2016-06-02 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan
CN102816858B (zh) * 2012-09-06 2014-02-19 上海源奇生物医药科技有限公司 一种检测ugt1a1基因型的引物和探针、及其试剂盒
CN102899406B (zh) * 2012-09-19 2014-06-04 长沙三济生物科技有限公司 定性检测尿苷二磷酸葡萄糖醛酸基转移酶1a1基因分型的测序引物对及其试剂盒
CN105177115B (zh) * 2014-11-17 2018-06-15 步迅 一种用于指导伊立替康类化疗药物个体化治疗的ugt1a1联合基因位点荧光检测试剂盒
CN104388572A (zh) * 2014-12-09 2015-03-04 苏州旷远生物分子技术有限公司 用于检测人ugt1a1基因多态性的引物、探针、荧光pcr试剂盒和方法
CN104946784A (zh) * 2015-07-20 2015-09-30 武汉友芝友医疗科技有限公司 人类ugt1a1基因多态性检测特异性引物和试剂盒
CN108570499B (zh) * 2018-01-15 2020-08-28 新开源禄西（南京）生物科技有限公司 一种ugt1a1基因的快速扩增试剂盒及扩增方法
CN109371127A (zh) * 2018-10-22 2019-02-22 江苏美因康生物科技有限公司 一种同时快速检测ugt1a1*6型与ugt1a1*28型基因多态性的试剂盒及方法
CN109913480B (zh) * 2019-03-21 2022-05-31 临沂大学 一种蝗虫尿苷二磷酸葡萄糖醛酸转移酶基因及其应用
CN117904281B (zh) * 2024-01-29 2024-11-22 上海科亦生物科技有限公司 检测ugt1a1基因多态性的引物组及试剂盒与方法

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US8357516B2 (en) 2013-01-22
CN102168141A (zh) 2011-08-31
CN102168141B (zh) 2013-10-23
EP2463365B1 (en) 2013-09-18
KR101153058B1 (ko) 2012-06-04
KR20110026025A (ko) 2011-03-14
KR20080101922A (ko) 2008-11-21
US9175272B2 (en) 2015-11-03
EP2463365A1 (en) 2012-06-13
US20090208954A1 (en) 2009-08-20
CN102168140A (zh) 2011-08-31
EP2071025A1 (en) 2009-06-17
CN101506362A (zh) 2009-08-12
EP2071025A4 (en) 2009-12-09
WO2008066136A1 (en) 2008-06-05
CN101506362B (zh) 2012-09-05
JP5307538B2 (ja) 2013-10-02
US20110281265A1 (en) 2011-11-17
CN102168140B (zh) 2013-10-23
JPWO2008066136A1 (ja) 2010-03-11

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