KR101002374B1 - 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물 - Google Patents

수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물 Download PDF

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Publication number
KR101002374B1
KR101002374B1 KR1020047013177A KR20047013177A KR101002374B1 KR 101002374 B1 KR101002374 B1 KR 101002374B1 KR 1020047013177 A KR1020047013177 A KR 1020047013177A KR 20047013177 A KR20047013177 A KR 20047013177A KR 101002374 B1 KR101002374 B1 KR 101002374B1
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South Korea
Prior art keywords
formulation
soluble cellulose
weight
water
pharmaceutical composition
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Expired - Lifetime
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KR1020047013177A
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English (en)
Korean (ko)
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KR20040088524A (ko
Inventor
겔레트폴리챠드
파커마이클데비스
드마터스마르셀
Original Assignee
아스트라제네카 아베
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27767732&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101002374(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0204392A external-priority patent/GB0204392D0/en
Priority claimed from GB0212462A external-priority patent/GB0212462D0/en
Priority claimed from GB0213267A external-priority patent/GB0213267D0/en
Application filed by 아스트라제네카 아베 filed Critical 아스트라제네카 아베
Publication of KR20040088524A publication Critical patent/KR20040088524A/ko
Application granted granted Critical
Publication of KR101002374B1 publication Critical patent/KR101002374B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020047013177A 2002-02-26 2003-02-24 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물 Expired - Lifetime KR101002374B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0204392.5 2002-02-26
GB0204392A GB0204392D0 (en) 2002-02-26 2002-02-26 Pharmaceutical compound
GB0212462.6 2002-05-30
GB0212462A GB0212462D0 (en) 2002-05-30 2002-05-30 Pharmaceutical compound
GB0213267.8 2002-06-11
GB0213267A GB0213267D0 (en) 2002-06-11 2002-06-11 Pharmaceutical composition
PCT/GB2003/000803 WO2003072139A1 (en) 2002-02-26 2003-02-24 Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020107016079A Division KR20100090726A (ko) 2002-02-26 2003-02-24 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물

Publications (2)

Publication Number Publication Date
KR20040088524A KR20040088524A (ko) 2004-10-16
KR101002374B1 true KR101002374B1 (ko) 2010-12-17

Family

ID=27767732

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020047013177A Expired - Lifetime KR101002374B1 (ko) 2002-02-26 2003-02-24 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물
KR1020107016079A Ceased KR20100090726A (ko) 2002-02-26 2003-02-24 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020107016079A Ceased KR20100090726A (ko) 2002-02-26 2003-02-24 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물

Country Status (29)

Country Link
US (2) US20050163835A1 (enExample)
EP (1) EP1480679B1 (enExample)
JP (1) JP4544863B2 (enExample)
KR (2) KR101002374B1 (enExample)
CN (1) CN1326569C (enExample)
AR (1) AR038848A1 (enExample)
AT (1) ATE362771T1 (enExample)
AU (1) AU2003208444B2 (enExample)
BR (1) BRPI0307786B8 (enExample)
CA (1) CA2476587C (enExample)
CO (1) CO5601038A2 (enExample)
CY (1) CY1108026T1 (enExample)
DE (1) DE60313956T2 (enExample)
DK (1) DK1480679T3 (enExample)
ES (1) ES2286406T3 (enExample)
IL (2) IL163642A0 (enExample)
IS (1) IS2462B (enExample)
MX (1) MXPA04008307A (enExample)
MY (1) MY135609A (enExample)
NO (1) NO328658B1 (enExample)
NZ (1) NZ534513A (enExample)
PL (1) PL208114B1 (enExample)
PT (1) PT1480679E (enExample)
RU (1) RU2318518C2 (enExample)
SA (1) SA03240043B1 (enExample)
TW (1) TWI271193B (enExample)
UA (1) UA76325C2 (enExample)
UY (1) UY27682A1 (enExample)
WO (1) WO2003072139A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101739731B1 (ko) * 2015-12-31 2017-05-25 환인제약 주식회사 유당불내성 환자에게 투여가 가능하며, 복용편의성이 향상된 게피티니브를 함유하는 약제학적 조성물

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WO2008050209A1 (en) 2006-10-27 2008-05-02 Pfizer Products Inc. Hydroxypropyl methyl cellulose hard capsules and process of manufacture
CA2686964A1 (en) * 2007-06-06 2008-12-11 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
MX2010001837A (es) 2007-08-17 2010-03-10 Actelion Pharmaceuticals Ltd Derivados de 4-pirimidinasulfamida.
US8728516B2 (en) * 2009-04-30 2014-05-20 Abbvie Inc. Stabilized lipid formulation of apoptosis promoter
TWI540132B (zh) * 2009-06-08 2016-07-01 亞培公司 Bcl-2族群抑制劑之口服醫藥劑型
TWI532484B (zh) * 2009-06-08 2016-05-11 艾伯維有限公司 包含凋亡促進劑之固態分散劑
BRPI1015941A2 (pt) * 2009-07-02 2016-04-19 Wyeth Llc formulações de comprimido de 3-cianoquinolina e uso das mesmas.
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JP4574742B1 (ja) * 2010-04-08 2010-11-04 有限会社ミールジャパン プロポリス組成物
UA113500C2 (xx) 2010-10-29 2017-02-10 Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб
ES2699205T3 (es) 2010-10-29 2019-02-07 Abbvie Inc Dispersiones sólidas que contienen un agente que induce la apoptosis
AU2011332043C1 (en) 2010-11-23 2016-11-10 Abbvie Inc. Salts and crystalline forms of an apoptosis-inducing agent
WO2012071340A1 (en) 2010-11-23 2012-05-31 Metamagnetics Inc. Antenna module having reduced size, high gain, and increased power efficiency
NZ708508A (en) 2010-11-23 2016-06-24 Abbvie Bahamas Ltd Methods of treatment using selective bcl-2 inhibitors
CN102631347B (zh) * 2012-05-03 2014-06-25 石药集团中奇制药技术(石家庄)有限公司 一种吉非替尼药物组合物及其制备方法
CN113372358B (zh) 2012-09-28 2024-05-14 武田药品工业株式会社 噻吩并嘧啶衍生物的制备方法
US20140275082A1 (en) 2013-03-14 2014-09-18 Abbvie Inc. Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
KR101332829B1 (ko) * 2013-05-31 2013-11-27 재단법인 통합의료진흥원 보중익기탕을 포함하는 폐암 치료용 조성물
GB201400034D0 (en) 2014-01-02 2014-02-19 Astrazeneca Ab Pharmaceutical Compositions comprising AZD9291
KR101721831B1 (ko) * 2014-11-06 2017-03-31 주식회사 종근당 로베글리타존을 함유하는 경구 투여용 약제학적 조성물
WO2016096999A1 (en) * 2014-12-19 2016-06-23 Synthon B.V. Pharmaceutical composition comprising gefifinib
SI4233847T1 (sl) * 2015-02-26 2025-02-28 Takeda Pharmaceutical Company Limited Tableta, ki vsebuje derivat metoksiuree in delce manitola
JP6739289B2 (ja) * 2016-08-25 2020-08-12 日本化薬株式会社 ゲフィチニブを有効成分とする医薬錠剤の製造方法
AU2017334035B2 (en) 2016-09-30 2022-11-24 Sumitomo Pharma Switzerland Gmbh Treatment of prostate cancer
CN108096251B (zh) * 2016-11-24 2021-11-16 江苏恒瑞医药股份有限公司 一种吉非替尼药物组合物及其制备方法
CN107007562B (zh) * 2017-02-16 2020-10-27 南京优科制药有限公司 一种吉非替尼片剂及其制备方法

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US20060088592A1 (en) 2004-04-28 2006-04-27 Seung-Ho Choi Oral formulation for delivery of poorly absorbed drugs

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US20060088592A1 (en) 2004-04-28 2006-04-27 Seung-Ho Choi Oral formulation for delivery of poorly absorbed drugs

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101739731B1 (ko) * 2015-12-31 2017-05-25 환인제약 주식회사 유당불내성 환자에게 투여가 가능하며, 복용편의성이 향상된 게피티니브를 함유하는 약제학적 조성물
WO2017116031A1 (ko) * 2015-12-31 2017-07-06 환인제약 주식회사 유당불내성 환자에게 투여가 가능하며, 복용편의성이 향상된 게피티니브를 함유하는 약제학적 조성물

Also Published As

Publication number Publication date
CN1638805A (zh) 2005-07-13
IS7420A (is) 2004-08-24
US20090186890A1 (en) 2009-07-23
KR20100090726A (ko) 2010-08-16
MY135609A (en) 2008-05-30
CO5601038A2 (es) 2006-01-31
DE60313956D1 (de) 2007-07-05
UY27682A1 (es) 2003-10-31
IL163642A (en) 2007-07-24
TWI271193B (en) 2007-01-21
NZ534513A (en) 2007-04-27
WO2003072139A1 (en) 2003-09-04
TW200304379A (en) 2003-10-01
AR038848A1 (es) 2005-01-26
RU2004129280A (ru) 2005-06-10
CY1108026T1 (el) 2013-09-04
KR20040088524A (ko) 2004-10-16
ATE362771T1 (de) 2007-06-15
CN1326569C (zh) 2007-07-18
CA2476587C (en) 2010-05-04
US20050163835A1 (en) 2005-07-28
UA76325C2 (uk) 2006-07-17
PL208114B1 (pl) 2011-03-31
DK1480679T3 (da) 2007-09-03
ES2286406T3 (es) 2007-12-01
BRPI0307786B8 (pt) 2021-05-25
BR0307786A (pt) 2004-12-07
DE60313956T2 (de) 2008-05-15
AU2003208444B2 (en) 2006-10-26
MXPA04008307A (es) 2004-11-26
AU2003208444A1 (en) 2003-09-09
SA03240043B1 (ar) 2007-05-06
PT1480679E (pt) 2007-07-18
HK1070585A1 (en) 2005-06-24
NO328658B1 (no) 2010-04-19
JP2005523293A (ja) 2005-08-04
RU2318518C2 (ru) 2008-03-10
EP1480679B1 (en) 2007-05-23
BRPI0307786B1 (pt) 2018-03-13
JP4544863B2 (ja) 2010-09-15
CA2476587A1 (en) 2003-09-04
PL372215A1 (en) 2005-07-11
EP1480679A1 (en) 2004-12-01
IS2462B (is) 2008-11-15
NO20043866L (no) 2004-09-15
IL163642A0 (en) 2005-12-18

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