KR100877306B1 - 세포 조직체 마이크로칩 및 세포 조직체의 형성 방법 - Google Patents

세포 조직체 마이크로칩 및 세포 조직체의 형성 방법 Download PDF

Info

Publication number
KR100877306B1
KR100877306B1 KR1020077010597A KR20077010597A KR100877306B1 KR 100877306 B1 KR100877306 B1 KR 100877306B1 KR 1020077010597 A KR1020077010597 A KR 1020077010597A KR 20077010597 A KR20077010597 A KR 20077010597A KR 100877306 B1 KR100877306 B1 KR 100877306B1
Authority
KR
South Korea
Prior art keywords
cell
cells
adhesive
microchip
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020077010597A
Other languages
English (en)
Korean (ko)
Other versions
KR20070065905A (ko
Inventor
코지 나카자와
준지 후쿠다
Original Assignee
자이단호진 기타큐슈산교가쿠쥬쓰스이신키코
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 자이단호진 기타큐슈산교가쿠쥬쓰스이신키코 filed Critical 자이단호진 기타큐슈산교가쿠쥬쓰스이신키코
Publication of KR20070065905A publication Critical patent/KR20070065905A/ko
Application granted granted Critical
Publication of KR100877306B1 publication Critical patent/KR100877306B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
KR1020077010597A 2004-10-29 2005-10-21 세포 조직체 마이크로칩 및 세포 조직체의 형성 방법 Expired - Fee Related KR100877306B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JPJP-P-2004-00315600 2004-10-29
JP2004315600A JP3981929B2 (ja) 2004-10-29 2004-10-29 細胞組織体マイクロチップ

Publications (2)

Publication Number Publication Date
KR20070065905A KR20070065905A (ko) 2007-06-25
KR100877306B1 true KR100877306B1 (ko) 2009-01-07

Family

ID=36227729

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077010597A Expired - Fee Related KR100877306B1 (ko) 2004-10-29 2005-10-21 세포 조직체 마이크로칩 및 세포 조직체의 형성 방법

Country Status (7)

Country Link
US (1) US8652847B2 (https=)
EP (1) EP1806394B1 (https=)
JP (1) JP3981929B2 (https=)
KR (1) KR100877306B1 (https=)
CN (1) CN101048493B (https=)
DE (1) DE602005017924D1 (https=)
WO (1) WO2006046490A1 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4033265B2 (ja) * 2004-10-29 2008-01-16 財団法人北九州産業学術推進機構 細胞組織体マイクロデバイス
US9121003B2 (en) 2007-09-12 2015-09-01 Kitakyushu Foundation For The Advancement Of Industry, Science And Technology Cell culture instrument and cell culture method using the same
US9394514B2 (en) 2009-06-23 2016-07-19 Hitachi, Ltd. Culture substrate, culture sheet, and cell culture method
JP5730499B2 (ja) * 2010-05-07 2015-06-10 株式会社日立製作所 培養器材
JP5730472B2 (ja) * 2009-06-23 2015-06-10 株式会社日立製作所 培養基材、及び細胞培養方法
JP5688695B2 (ja) * 2010-01-29 2015-03-25 独立行政法人理化学研究所 基板、細胞培養装置、細胞チップおよび培養方法
US20130323839A1 (en) * 2010-12-22 2013-12-05 Hitachi, Ltd. Culture Substrate and Culture Sheet
US10866169B2 (en) 2012-10-17 2020-12-15 Konica Minolta, Inc. Method for recovering rare cells and method for detecting rare cells
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
WO2015118873A1 (en) * 2014-02-05 2015-08-13 Toyo Gosei Co., Ltd. Plates for culture of biological samples
JP6930914B2 (ja) 2014-10-29 2021-09-01 コーニング インコーポレイテッド 灌流バイオリアクタ・プラットフォーム
EP3212759A1 (en) 2014-10-29 2017-09-06 Corning Incorporated Cell culture insert
WO2016069930A1 (en) 2014-10-29 2016-05-06 Corning Incorporated Microwell design and fabrication for generation of cell culture aggregates
JP5909543B2 (ja) * 2014-12-26 2016-04-26 株式会社日立製作所 培養器材
JP5984998B2 (ja) * 2015-04-08 2016-09-06 株式会社日立製作所 培養基材
CN104774763A (zh) * 2015-04-24 2015-07-15 何向锋 一种微片式单细胞克隆分离培养板及单细胞克隆分离方法
CN109126912B (zh) * 2017-06-15 2021-02-02 上海微创医疗器械（集团）有限公司 生物芯片及其制备方法
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
EP3652290B1 (en) 2017-07-14 2022-05-04 Corning Incorporated 3d cell culture vessels for manual or automatic media exchange
JP7195302B2 (ja) 2017-07-14 2022-12-23 コーニング インコーポレイテッド ３ｄ培養のための細胞培養容器及び３ｄ細胞の培養方法
WO2020013207A1 (ja) 2018-07-10 2020-01-16 株式会社日本触媒 細胞培養用シート
WO2020013847A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface
WO2020013845A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Cell culture vessels with stabilizer devices
CN111065725B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 包括具有互联的壁的微板的流体装置
CN113278523B (zh) * 2021-05-08 2024-11-15 上海碧博生物医药工程有限公司 具有细胞定位功能的细胞培养板及其制备方法和细胞定位的方法
EP4289934B1 (en) * 2022-06-09 2025-12-31 Finnadvance Oy CELL CULTURE MEMBRANE STRUCTURE, ITS PRODUCTION PROCESSES, CELL CULTURE PLATE, CELL CULTURE APPARATUS INCLUDING THE CELL CULTURE MEMBRANE STRUCTURE AND CELL CULTURE PROCESSES USING THE CELL CULTURE APPARATUS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0402718B1 (en) 1989-06-03 1994-11-02 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Control of cell arrangement
JP3887435B2 (ja) 1996-07-12 2007-02-28 第一製薬株式会社 スフェロイド形成促進剤
AU2001283492A1 (en) * 2000-07-11 2002-01-21 The Johns Hopkins University School Of Medicine Methods of patterning protein and cell adhesivity
JP4002720B2 (ja) * 2000-11-22 2007-11-07 独立行政法人科学技術振興機構 一細胞長期培養顕微観察装置
JP2002357604A (ja) * 2001-04-17 2002-12-13 Nisshinbo Ind Inc 反応容器及びこれを用いる生物学的に活性な物質の分析方法
AU2002257289A1 (en) * 2001-05-17 2002-11-25 The Board Of Trustees Of The Leland Stanford Junior University Device and method for three-dimensional spatial localization and functional interconnection of different types of cells
AU2002352696A1 (en) 2001-11-16 2003-06-10 University Of North Carolina At Chapel Hill Cell substrates and methods of use thereof
CN1490400A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 毛细管微包被法控制细胞空间分布、形状和大小及其应用
CN1490401A (zh) * 2002-10-17 2004-04-21 中国科学院力学研究所 低自由能表面微处理控制细胞空间定位及应用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biomaterials. Vol.24(18), pp.3021-3026 (2003)

Also Published As

Publication number Publication date
JP3981929B2 (ja) 2007-09-26
JP2006121991A (ja) 2006-05-18
EP1806394B1 (en) 2009-11-25
US20080138900A1 (en) 2008-06-12
WO2006046490A1 (ja) 2006-05-04
CN101048493B (zh) 2012-07-18
KR20070065905A (ko) 2007-06-25
CN101048493A (zh) 2007-10-03
EP1806394A4 (en) 2008-10-22
EP1806394A1 (en) 2007-07-11
DE602005017924D1 (de) 2010-01-07
US8652847B2 (en) 2014-02-18

Similar Documents

Publication Publication Date Title
KR100877306B1 (ko) 세포 조직체 마이크로칩 및 세포 조직체의 형성 방법
JP4576539B2 (ja) 細胞培養器具及びこれを用いた細胞培養方法
JP5234428B2 (ja) 細胞集合体形成器具、細胞集合体培養器具、細胞集合体転写キット及び細胞集合体の培養方法
Li et al. Biology on a chip: microfabrication for studying the behavior of cultured cells
US6734000B2 (en) Nanoporous silicon support containing macropores for use as a bioreactor
US10571461B2 (en) Multi-well micropatterning by ablation
JP2005027598A (ja) 細胞培養チップ及び培養器、それらを用いた細胞培養方法、球状細胞組織体を担持させた細胞担持モジュール、球状細胞組織体
JP2012509663A (ja) 細胞培養のための、突起間隔を開けた基板および装置
US20110250679A1 (en) Methods and Compositions for High-Resolution Micropatterning for Cell Culture
EP2180042A1 (en) Methods and device to constrain multicellular arrangements in stable, stationary and reproducible spatial configuration
JP4033265B2 (ja) 細胞組織体マイクロデバイス
Mai et al. MatriGrid® based biological morphologies: Tools for 3D cell culturing
Tan et al. Adhesion contact dynamics of primary hepatocytes on poly (ethylene terephthalate) surface
Desai et al. Microtextured cell culture platforms: Biomimetic substrates for the growth of cardiac myocytes and fibroblasts
Otsuka Micropatterning of cell aggregate in three dimension for in vivo mimicking cell culture
JP4332653B2 (ja) 組織体形成方法及び組織体形成キット
KR102666815B1 (ko) 패턴이 형성된 근육세포 배양 장치 및 이의 배양 방법
Hsieh et al. Applications of fabricated micro-and nanostructures in biomedicine
Singh et al. Stem‐Cell Nanoengineering: Explorations in a Rapidly Moving Field
Serena et al. Microtechnology for stem cell culture
Peterson Contact Guidance of Mesenchymal Stem Cells on Micropatterned Polydimethysiloxane

Legal Events

Date Code Title Description
A201 Request for examination
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

P14-X000 Amendment of ip right document requested

St.27 status event code: A-5-5-P10-P14-nap-X000

P15-X000 Request for amendment of ip right document rejected

St.27 status event code: A-5-5-P10-P15-nap-X000

FPAY Annual fee payment

Payment date: 20121130

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

FPAY Annual fee payment

Payment date: 20131218

Year of fee payment: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20141230

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20141230