KR100854198B1 - 섬유아세포 성장 인자 21의 뮤테인 - Google Patents

섬유아세포 성장 인자 21의 뮤테인 Download PDF

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Publication number
KR100854198B1
KR100854198B1 KR1020077004881A KR20077004881A KR100854198B1 KR 100854198 B1 KR100854198 B1 KR 100854198B1 KR 1020077004881 A KR1020077004881 A KR 1020077004881A KR 20077004881 A KR20077004881 A KR 20077004881A KR 100854198 B1 KR100854198 B1 KR 100854198B1
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fgf
muteins
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mutein
amino acid
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Korean (ko)
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KR20070050454A (ko
Inventor
크리스토퍼 칼 프라이
리후아 후앙
라드밀라 미카노빅
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일라이 릴리 앤드 캄파니
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
KR1020077004881A 2004-09-02 2005-07-26 섬유아세포 성장 인자 21의 뮤테인 Expired - Fee Related KR100854198B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60680504P 2004-09-02 2004-09-02
US60/606,805 2004-09-02

Publications (2)

Publication Number Publication Date
KR20070050454A KR20070050454A (ko) 2007-05-15
KR100854198B1 true KR100854198B1 (ko) 2008-08-26

Family

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Family Applications (1)

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KR1020077004881A Expired - Fee Related KR100854198B1 (ko) 2004-09-02 2005-07-26 섬유아세포 성장 인자 21의 뮤테인

Country Status (21)

Country Link
US (1) US7582607B2 (enExample)
EP (2) EP1789442B1 (enExample)
JP (1) JP4809352B2 (enExample)
KR (1) KR100854198B1 (enExample)
CN (1) CN101010338B (enExample)
AT (1) ATE444307T1 (enExample)
AU (1) AU2005283025B2 (enExample)
BR (1) BRPI0514790A (enExample)
CA (1) CA2575753A1 (enExample)
DE (1) DE602005016946D1 (enExample)
DK (1) DK1789442T3 (enExample)
EA (1) EA011390B1 (enExample)
ES (1) ES2332057T3 (enExample)
HR (1) HRP20090597T1 (enExample)
IL (1) IL181573A0 (enExample)
MX (1) MX2007002616A (enExample)
NO (1) NO20071327L (enExample)
PL (1) PL1789442T3 (enExample)
PT (1) PT1789442E (enExample)
SI (1) SI1789442T1 (enExample)
WO (1) WO2006028595A2 (enExample)

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Publication number Publication date
SI1789442T1 (sl) 2010-01-29
KR20070050454A (ko) 2007-05-15
US20080103096A1 (en) 2008-05-01
US7582607B2 (en) 2009-09-01
HRP20090597T1 (hr) 2009-12-31
IL181573A0 (en) 2007-07-04
JP4809352B2 (ja) 2011-11-09
ES2332057T3 (es) 2010-01-25
PT1789442E (pt) 2009-11-11
EP2161281A1 (en) 2010-03-10
BRPI0514790A (pt) 2008-06-24
EA200700533A1 (ru) 2007-08-31
AU2005283025B2 (en) 2011-06-30
WO2006028595A2 (en) 2006-03-16
ATE444307T1 (de) 2009-10-15
DE602005016946D1 (de) 2009-11-12
EA011390B1 (ru) 2009-02-27
JP2008511323A (ja) 2008-04-17
AU2005283025A1 (en) 2006-03-16
CN101010338A (zh) 2007-08-01
MX2007002616A (es) 2007-05-16
EP1789442B1 (en) 2009-09-30
NO20071327L (no) 2007-05-29
CN101010338B (zh) 2011-06-15
WO2006028595A3 (en) 2007-01-18
EP1789442A2 (en) 2007-05-30
CA2575753A1 (en) 2006-03-16
PL1789442T3 (pl) 2010-02-26
DK1789442T3 (da) 2009-11-16

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