KR100679778B1 - PTHrP 유사체를 사용하는 골절 치료법 - Google Patents
PTHrP 유사체를 사용하는 골절 치료법 Download PDFInfo
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- KR100679778B1 KR100679778B1 KR1020007002454A KR20007002454A KR100679778B1 KR 100679778 B1 KR100679778 B1 KR 100679778B1 KR 1020007002454 A KR1020007002454 A KR 1020007002454A KR 20007002454 A KR20007002454 A KR 20007002454A KR 100679778 B1 KR100679778 B1 KR 100679778B1
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- South Korea
- Prior art keywords
- pthrp
- seq
- analogs
- bone
- amino acid
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- Expired - Lifetime
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5832497P | 1997-09-09 | 1997-09-09 | |
| US60/058,324 | 1997-09-09 | ||
| PCT/EP1998/005550 WO1999012561A2 (en) | 1997-09-09 | 1998-09-02 | FRACTURE HEALING USING PTHrP ANALOGS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010023795A KR20010023795A (ko) | 2001-03-26 |
| KR100679778B1 true KR100679778B1 (ko) | 2007-02-07 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007002454A Expired - Lifetime KR100679778B1 (ko) | 1997-09-09 | 1998-09-02 | PTHrP 유사체를 사용하는 골절 치료법 |
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|---|---|
| US (1) | US6583114B2 (enExample) |
| EP (1) | EP1005359B1 (enExample) |
| JP (1) | JP2002509854A (enExample) |
| KR (1) | KR100679778B1 (enExample) |
| CN (1) | CN1210059C (enExample) |
| AR (1) | AR015435A1 (enExample) |
| AT (1) | ATE297754T1 (enExample) |
| AU (1) | AU752925B2 (enExample) |
| BR (1) | BR9812068A (enExample) |
| CA (1) | CA2302255C (enExample) |
| CO (1) | CO4890856A1 (enExample) |
| CZ (1) | CZ298701B6 (enExample) |
| DE (1) | DE69830591T2 (enExample) |
| ES (1) | ES2244090T3 (enExample) |
| HR (1) | HRP20000109A2 (enExample) |
| HU (1) | HU226866B1 (enExample) |
| IL (2) | IL134719A0 (enExample) |
| MA (1) | MA26545A1 (enExample) |
| MY (1) | MY121291A (enExample) |
| NO (1) | NO323740B1 (enExample) |
| NZ (1) | NZ502970A (enExample) |
| PE (1) | PE117399A1 (enExample) |
| PL (1) | PL195703B1 (enExample) |
| RS (1) | RS49707B (enExample) |
| RU (1) | RU2224539C2 (enExample) |
| SA (1) | SA98190565B1 (enExample) |
| TR (1) | TR200000649T2 (enExample) |
| TW (1) | TW552139B (enExample) |
| UY (1) | UY25172A1 (enExample) |
| WO (1) | WO1999012561A2 (enExample) |
| ZA (1) | ZA988030B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1059933T1 (en) * | 1998-08-19 | 2003-04-30 | Eli Lilly & Company | Use of parathyroide hormone consisting of aminoacid sequence 1-34 of human parathyroid hormone for reducing the risk of both vertebral and non vertebral bone fracture |
| EP1769804B1 (en) * | 1998-08-19 | 2012-09-19 | Eli Lilly And Company | hPTH(1-34) for use in preventing or reducing the incidence or severity of vertebral and / or non vertebral fracture in a male human |
| US20040033950A1 (en) | 2000-09-26 | 2004-02-19 | Hock Janet M. | Method of increasing bone toughness and stiffness and reducing fractures |
| DZ2873A1 (fr) * | 1998-08-19 | 2003-12-15 | Lilly Co Eli | Procédé pour augmenter la dureté et la rigidité osseuse. |
| CA2245903A1 (en) * | 1998-09-28 | 2000-03-28 | Mcgill University | Use of pex in the treatment of metabolic bone diseases |
| ES2232434T3 (es) | 1999-03-05 | 2005-06-01 | Duke University | Analogos de prostaglandinas c-16 fp selectivas insaturadas. |
| US20020037914A1 (en) | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| US6560487B1 (en) * | 2000-05-08 | 2003-05-06 | International Rehabilitative Sciences, Inc. | Electro-medical device for use with biologics |
| US6675048B2 (en) * | 2000-05-08 | 2004-01-06 | International Rehabilitative Sciences, Inc. | Electro-medical device for use with biologics |
| US6393328B1 (en) * | 2000-05-08 | 2002-05-21 | International Rehabilitative Sciences, Inc. | Multi-functional portable electro-medical device |
| EP1531855A4 (en) * | 2002-01-10 | 2009-07-22 | Osteotrophin Llc | TREATMENT OF BONE DISEASES WITH SKELETTAL ANABOLIKA |
| US7399826B1 (en) | 2003-10-02 | 2008-07-15 | Ali Sadat M | Peptide for promoting healing of fractures |
| WO2006042152A2 (en) * | 2004-10-08 | 2006-04-20 | Forbes Medi-Tech (Research) Inc. | Vasoactive intestinal polypeptide pharmaceuticals |
| CN101355959B (zh) * | 2005-11-10 | 2013-02-27 | 密歇根理工大学管理委员会 | 黑熊甲状旁腺素和使用黑熊甲状旁腺素的方法 |
| US20090022684A1 (en) * | 2006-05-09 | 2009-01-22 | Paul Morley | Methods for hematopoietic stimulation |
| US7803770B2 (en) | 2006-10-03 | 2010-09-28 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
| USRE49444E1 (en) | 2006-10-03 | 2023-03-07 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
| SI2957278T1 (sl) | 2006-10-03 | 2017-09-29 | Radius Health, Inc. | Stabilni sestavek, ki obsega PTHrP, in njegova uporaba |
| EP1961765A1 (en) * | 2006-12-08 | 2008-08-27 | Zealand Pharma A/S | Truncated PTH peptides with a cyclic conformation |
| JP5564167B2 (ja) * | 2008-05-22 | 2014-07-30 | 日本たばこ産業株式会社 | 苦味マスキング剤及び苦味低減方法 |
| US8870876B2 (en) | 2009-02-13 | 2014-10-28 | Tarsus Medical Inc. | Methods and devices for treating hallux valgus |
| US8563513B2 (en) | 2009-03-27 | 2013-10-22 | Van Andel Research Institute | Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use |
| US8277459B2 (en) | 2009-09-25 | 2012-10-02 | Tarsus Medical Inc. | Methods and devices for treating a structural bone and joint deformity |
| EP2509996A1 (en) | 2009-12-07 | 2012-10-17 | Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
| US8652141B2 (en) | 2010-01-21 | 2014-02-18 | Tarsus Medical Inc. | Methods and devices for treating hallux valgus |
| US8696719B2 (en) | 2010-06-03 | 2014-04-15 | Tarsus Medical Inc. | Methods and devices for treating hallux valgus |
| PL3122426T3 (pl) | 2014-03-28 | 2023-05-15 | Duke University | Leczenie raka sutka z zastosowaniem selektywnych modulatorów receptora estrogenowego |
| CN104146961B (zh) * | 2014-07-04 | 2018-02-27 | 深圳职业技术学院 | 一种薄膜蒸发法制备载细胞因子和骨蛋白微球的方法 |
| WO2016176665A1 (en) | 2015-04-29 | 2016-11-03 | Radius Health, Inc. | Methods of treating cancer |
| WO2017007777A2 (en) * | 2015-07-06 | 2017-01-12 | Zhengxin Dong | NOVEL FORMULATIONS OF PTHrP ANALOGUE |
| AU2017253674B2 (en) | 2016-04-18 | 2021-07-29 | Kindeva Drug Delivery L.P. | Formulations of abaloparatide, transdermal patches thereof, and uses thereof |
| EP4374925A3 (en) | 2017-01-05 | 2025-01-15 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad1901-2hcl |
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| EP4027899A4 (en) * | 2019-09-12 | 2023-08-16 | Radius Health, Inc. | METHODS OF ENHANCING SPINE FUSION USING ABALOPARATIDE |
| CN112646042A (zh) * | 2019-10-10 | 2021-04-13 | 陕西麦科奥特科技有限公司 | 活性多肽化合物 |
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