KR100642293B1 - 제 8 인자 폴리펩티드 - Google Patents
제 8 인자 폴리펩티드 Download PDFInfo
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- KR100642293B1 KR100642293B1 KR1020047021206A KR20047021206A KR100642293B1 KR 100642293 B1 KR100642293 B1 KR 100642293B1 KR 1020047021206 A KR1020047021206 A KR 1020047021206A KR 20047021206 A KR20047021206 A KR 20047021206A KR 100642293 B1 KR100642293 B1 KR 100642293B1
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- 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
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- 238000001291 vacuum drying Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
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- 229910000166 zirconium phosphate Inorganic materials 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/10—Factor VIII, AHF; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/353,753 US7041635B2 (en) | 2003-01-28 | 2003-01-28 | Factor VIII polypeptide |
| US10/353,753 | 2003-01-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20050044776A KR20050044776A (ko) | 2005-05-12 |
| KR100642293B1 true KR100642293B1 (ko) | 2006-11-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020047021206A Expired - Lifetime KR100642293B1 (ko) | 2003-01-28 | 2003-10-27 | 제 8 인자 폴리펩티드 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7041635B2 (enExample) |
| EP (2) | EP1587832B1 (enExample) |
| KR (1) | KR100642293B1 (enExample) |
| CN (1) | CN100404552C (enExample) |
| AU (1) | AU2003274766B8 (enExample) |
| BE (1) | BE2017C021I2 (enExample) |
| CA (1) | CA2514646C (enExample) |
| DK (2) | DK1587832T3 (enExample) |
| ES (1) | ES2446041T3 (enExample) |
| FR (1) | FR17C1024I2 (enExample) |
| LU (1) | LUC00023I2 (enExample) |
| NL (1) | NL300878I2 (enExample) |
| WO (1) | WO2004067566A1 (enExample) |
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| WO2024081309A1 (en) | 2022-10-11 | 2024-04-18 | Sigilon Therapeutics, Inc. | Engineered cells and implantable elements for treatment of disease |
| TW202517669A (zh) | 2023-07-05 | 2025-05-01 | 日商武田藥品工業股份有限公司 | 用於Ａ型血友病之基因療法的編碼表現增加之重組ＦＶｌｌｌ變異體的病毒載體 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3683980D1 (de) | 1985-04-12 | 1992-04-02 | Genetics Inst | Neue prokoagulierungsproteine. |
| US5451521A (en) | 1986-05-29 | 1995-09-19 | Genetics Institute, Inc. | Procoagulant proteins |
| US5422260A (en) | 1986-05-29 | 1995-06-06 | Genetics Institute, Inc. -Legal Affairs | Human factor VIII:c muteins |
| US5610278A (en) | 1986-06-24 | 1997-03-11 | Novo Nordisk A/S | Process for producing a coagulation active complex of factor VIII fragments |
| FR2619314B1 (fr) | 1987-08-11 | 1990-06-15 | Transgene Sa | Analogue du facteur viii, procede de preparation et composition pharmaceutique le contenant |
| EP0638091B1 (en) * | 1992-04-30 | 2005-12-07 | Probitas Pharma Inc. | Improved solubilization and stabilization of factor viii complex |
| ATE319817T1 (de) | 1996-04-24 | 2006-03-15 | Univ Michigan | Gegen inaktivierung resistenter faktor viii |
| AU1598200A (en) | 1998-10-23 | 2000-05-15 | Trustees Of The University Of Pennsylvania, The | Systemic delivery of gene products via skin |
| WO2002102850A2 (en) | 2001-06-15 | 2002-12-27 | Schuh Andre C | Gene therapy for hemophilia a |
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| US7041635B2 (en) | 2006-05-09 |
| ES2446041T3 (es) | 2014-03-06 |
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| US20040147436A1 (en) | 2004-07-29 |
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| FR17C1024I2 (fr) | 2019-07-19 |
| AU2003274766A1 (en) | 2004-08-23 |
| CN100404552C (zh) | 2008-07-23 |
| EP2253645B1 (en) | 2016-03-23 |
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| EP2253645A3 (en) | 2011-02-16 |
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| CN1745100A (zh) | 2006-03-08 |
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