KR100452062B1 - - Google Patents

Info

Publication number
KR100452062B1
KR100452062B1 KR10-1998-0706784A KR19980706784A KR100452062B1 KR 100452062 B1 KR100452062 B1 KR 100452062B1 KR 19980706784 A KR19980706784 A KR 19980706784A KR 100452062 B1 KR100452062 B1 KR 100452062B1
Authority
KR
South Korea
Prior art keywords
nnr4
coor1
pxr
amidino
sic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR10-1998-0706784A
Other languages
English (en)
Korean (ko)
Other versions
KR19990087372A (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26232562&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100452062(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9602604A external-priority patent/FR2745569B1/fr
Priority claimed from FR9609557A external-priority patent/FR2751972B1/fr
Application filed filed Critical
Publication of KR19990087372A publication Critical patent/KR19990087372A/ko
Application granted granted Critical
Publication of KR100452062B1 publication Critical patent/KR100452062B1/ko
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1019980706784A 1996-03-01 1997-02-28 아미디늄류 관련 화합물, 이를 함유한 약학조성물, 및 이의용도 Granted KR19990087372A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9602604A FR2745569B1 (fr) 1996-03-01 1996-03-01 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
FR96/02,604 1996-03-01
FR9609557A FR2751972B1 (fr) 1996-07-30 1996-07-30 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
FR96/09,557 1996-07-30

Publications (2)

Publication Number Publication Date
KR19990087372A KR19990087372A (ko) 1999-12-27
KR100452062B1 true KR100452062B1 (enExample) 2005-04-08

Family

ID=26232562

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019980706784A Granted KR19990087372A (ko) 1996-03-01 1997-02-28 아미디늄류 관련 화합물, 이를 함유한 약학조성물, 및 이의용도

Country Status (18)

Country Link
US (2) US6143729A (enExample)
EP (1) EP0888379B1 (enExample)
JP (1) JP4271260B2 (enExample)
KR (1) KR19990087372A (enExample)
AT (1) ATE198599T1 (enExample)
AU (1) AU723998B2 (enExample)
BR (1) BRPI9707889B8 (enExample)
CZ (1) CZ295225B6 (enExample)
DE (1) DE69703878T2 (enExample)
DK (1) DK0888379T3 (enExample)
ES (1) ES2154453T3 (enExample)
GR (1) GR3035205T3 (enExample)
HU (1) HU228072B1 (enExample)
IL (1) IL125926A (enExample)
NO (1) NO311806B1 (enExample)
PT (1) PT888379E (enExample)
SK (1) SK283575B6 (enExample)
WO (1) WO1997031935A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884430B1 (en) * 1997-02-10 2005-04-26 Aventis Pharma S.A. Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
FR2763943B1 (fr) * 1997-05-28 1999-07-09 Rhone Poulenc Rorer Sa Composes, leur preparation et leur utilisation pour le transfert d'acides nucleiques dans les cellules
FR2777017B1 (fr) * 1998-04-02 2002-08-23 Rhone Poulenc Rorer Sa Nouveaux agents de transfert d'acides nucleiques, compositions les contenant et leurs applications
KR20010042318A (ko) * 1998-04-02 2001-05-25 아방티 파르마 소시에테 아노님 신규 핵산 전달제, 이를 함유하는 조성물 및 용도
DE10109898A1 (de) * 2001-02-21 2002-09-05 Novosom Gmbh Lipide mit veränderlicher Ladung
FR2824557B1 (fr) * 2001-05-14 2003-08-29 Aventis Pharma Sa Derives lipidiques de polythiouree
JP4276439B2 (ja) * 2001-05-14 2009-06-10 サントリオン ポリチオ尿素の脂質誘導体
FR2829136B1 (fr) 2001-08-29 2006-11-17 Aventis Pharma Sa Derives lipidiques d'aminoglycosides
EP1479985B1 (en) 2002-01-17 2017-06-14 Alfa Laval Corporate AB Submerged evaporator comprising a plate heat exchanger and a cylindric casing where the plate heat exchanger is arranged
JP4980893B2 (ja) * 2005-04-28 2012-07-18 日本曹達株式会社 新規なグアニジン化合物、製造方法及びそれらを含有する殺菌性組成物
EP2069500B1 (en) * 2006-10-04 2014-09-24 Centre National De La Recherche Scientifique (Cnrs) Compositions comprising a sirna and lipidic 4,5-disubstituted 2-deoxystreptamine ring aminoglycoside derivatives and uses thereof
EP2350296A4 (en) * 2008-11-17 2013-04-03 Enzon Pharmaceuticals Inc BRANCHED CATIONIC LIPIDS FOR THE SYSTEM FOR INTRODUCING NUCLEIC ACIDS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
KR960705771A (ko) * 1993-11-24 1996-11-08 벤자민 에프 맥그로우 구아니딘의 양쪽친화성 유도체(amphiphilic derivatives of guanidine)
US5777153A (en) * 1994-07-08 1998-07-07 Gilead Sciences, Inc. Cationic lipids
US6071890A (en) * 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
US5811406A (en) * 1995-06-07 1998-09-22 Regents Of The University Of California Dry powder formulations of polynucleotide complexes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. Biol. Chem. Vol.270(52): 313941-31396 (1995) *

Also Published As

Publication number Publication date
PT888379E (pt) 2001-05-31
SK118298A3 (en) 1999-02-11
JP2000506136A (ja) 2000-05-23
NO311806B1 (no) 2002-01-28
EP0888379B1 (fr) 2001-01-10
ES2154453T3 (es) 2001-04-01
AU1930497A (en) 1997-09-16
GR3035205T3 (en) 2001-04-30
DE69703878T2 (de) 2001-04-26
AU723998B2 (en) 2000-09-07
BR9707889A (pt) 2000-01-04
CZ295225B6 (cs) 2005-06-15
CZ277298A3 (cs) 1998-12-16
NO983691D0 (no) 1998-08-12
ATE198599T1 (de) 2001-01-15
JP4271260B2 (ja) 2009-06-03
HUP9902465A1 (hu) 1999-12-28
DK0888379T3 (da) 2001-01-29
IL125926A0 (en) 1999-04-11
EP0888379A1 (fr) 1999-01-07
SK283575B6 (sk) 2003-09-11
DE69703878D1 (de) 2001-02-15
US6316422B1 (en) 2001-11-13
WO1997031935A1 (fr) 1997-09-04
HU228072B1 (en) 2012-09-28
IL125926A (en) 2004-09-27
KR19990087372A (ko) 1999-12-27
NO983691L (no) 1998-08-12
BR9707889B1 (pt) 2010-03-23
BRPI9707889B8 (pt) 2016-11-08
US6143729A (en) 2000-11-07
HUP9902465A3 (en) 2009-10-28

Similar Documents

Publication Publication Date Title
ZA988826B (en) Acylsulfamoylbenzamides crop protection compositions comprising them and processes for their preparation
EP0528858A4 (en) Inhibitors of dipeptidyl-aminopeptidase type iv
IL126610A0 (en) N-(amidinophenyl)-n'-(subst.)-3h-2,4-benzodiazepin-3- one derivatives as factor xa inhibitors
GR3036017T3 (en) Heterocyclic fungicides
AU1324595A (en) Cyclic polyamines
DE69416119D1 (de) Harnstoff- und amidderivate und ihre verwendung zur kontrolle von zellmembranständigen kalium-kanälen
DE69420564D1 (de) Immunsuppressive und antiallergische verbindungen; z.b. n-(3-oxohexanoyl)-homoserinlacton
TR200800474T2 (tr) Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem.
YU89691A (sh) Postupak za dobijanje stereoselektivnih derivata fenilizoserina
AU4064597A (en) Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof
HUP9902465A1 (hu) Új amidínium-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
CA2176935A1 (fr) Arylpiperazines derivees d'indole comme ligands pour les recepteurs 5 ht1-like 5 ht1b et 5 ht1d
TW354318B (en) Viscosity conditioner
TR200001010T2 (tr) Ürokinaz önleyicileri olan izokinolinler.
BR9610876A (pt) Inibidores de protease de guanidino
ATE247955T1 (de) Selenophen-antitumormittel
ATE190334T1 (de) Azlacton-derivatisierte polyamide
MX9602949A (es) 2-oxa y tia-zolinas artropodicidas.
AU637204B2 (en) Aminic derivatives showing fungicidal activity
MX9800053A (es) Herbicidas de cis-2,3-expoxicicloalcanol bencilado.
MX9601017A (es) Derivados sustituidos de tiazolo [3,2-a] azepina.
TW344650B (en) Fungicidal compositions and the process for the preparation thereof
DK0674649T3 (da) Antiparasitiske midler
IT1271430B (it) Derivati di indenopiridazioni e benzocinnolinoni ad attivita' antitumorale
MY114151A (en) Analogs of thymosin

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 19980828

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20020219

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20031224

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20040713

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20040930

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20041001

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20070903

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20080903

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 20090917

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 20100901

Start annual number: 7

End annual number: 7

PR1001 Payment of annual fee

Payment date: 20110901

Start annual number: 8

End annual number: 8

FPAY Annual fee payment

Payment date: 20120917

Year of fee payment: 9

PR1001 Payment of annual fee

Payment date: 20120917

Start annual number: 9

End annual number: 9

FPAY Annual fee payment

Payment date: 20130909

Year of fee payment: 10

PR1001 Payment of annual fee

Payment date: 20130909

Start annual number: 10

End annual number: 10

FPAY Annual fee payment

Payment date: 20140917

Year of fee payment: 11

PR1001 Payment of annual fee

Payment date: 20140917

Start annual number: 11

End annual number: 11

PR1001 Payment of annual fee

Payment date: 20150901

Start annual number: 12

End annual number: 12

PR1001 Payment of annual fee

Payment date: 20160901

Start annual number: 13

End annual number: 13

PC1801 Expiration of term