KR100356040B1 - 포피로모나스 긴기발리스 관련 치주염의 진단 및 치료용 합성 펩타이드 구조체 - Google Patents

포피로모나스 긴기발리스 관련 치주염의 진단 및 치료용 합성 펩타이드 구조체 Download PDF

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Publication number
KR100356040B1
KR100356040B1 KR1019997010041A KR19997010041A KR100356040B1 KR 100356040 B1 KR100356040 B1 KR 100356040B1 KR 1019997010041 A KR1019997010041 A KR 1019997010041A KR 19997010041 A KR19997010041 A KR 19997010041A KR 100356040 B1 KR100356040 B1 KR 100356040B1
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South Korea
Prior art keywords
peptide
peptides
gingivalis
composition
antibody
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Expired - Fee Related
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KR1019997010041A
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English (en)
Korean (ko)
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KR20010020417A (ko
Inventor
레이놀즈에릭찰스
오브라이언-심프슨닐마틴
슬레이키스키나다
Original Assignee
더 유니버시티 오브 멜버른
빅토리안 데어리 인더스트리 오소리티
씨에스엘 리미티드
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Publication of KR20010020417A publication Critical patent/KR20010020417A/ko
Application granted granted Critical
Publication of KR100356040B1 publication Critical patent/KR100356040B1/ko
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Dental Preparations (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1019997010041A 1997-04-30 1998-04-30 포피로모나스 긴기발리스 관련 치주염의 진단 및 치료용 합성 펩타이드 구조체 Expired - Fee Related KR100356040B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPO6528 1997-04-30
AUPO6528A AUPO652897A0 (en) 1997-04-30 1997-04-30 Synthetic peptide constructs for the diagnosis and treatment of periodontitis

Publications (2)

Publication Number Publication Date
KR20010020417A KR20010020417A (ko) 2001-03-15
KR100356040B1 true KR100356040B1 (ko) 2002-10-18

Family

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Family Applications (1)

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KR1019997010041A Expired - Fee Related KR100356040B1 (ko) 1997-04-30 1998-04-30 포피로모나스 긴기발리스 관련 치주염의 진단 및 치료용 합성 펩타이드 구조체

Country Status (12)

Country Link
US (4) US7262271B2 (enExample)
EP (3) EP1985625B1 (enExample)
JP (1) JP4276300B2 (enExample)
KR (1) KR100356040B1 (enExample)
AT (1) ATE408618T1 (enExample)
AU (1) AUPO652897A0 (enExample)
CA (4) CA2639048C (enExample)
DE (1) DE69840027D1 (enExample)
DK (1) DK1017714T3 (enExample)
ES (1) ES2530510T3 (enExample)
NZ (1) NZ500451A (enExample)
WO (1) WO1998049192A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN627595A0 (en) * 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
DK2256205T3 (da) * 1997-12-10 2013-07-08 Csl Ltd Porphorymonas gingivalis-polypeptider og -polynukleotider
US8129500B2 (en) * 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
AUPP893999A0 (en) * 1999-03-01 1999-03-25 Csl Limited Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis
AUPQ485999A0 (en) * 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
US20070053923A1 (en) * 2003-01-30 2007-03-08 Ki-Seok Park Dna vaccine composition with enhanced immunogenicity
NZ554331A (en) * 2004-09-23 2009-04-30 Univ Melbourne Antigenic complex for the diagnosis and treatment of porphyromonas gingivalis infection
JP2009544279A (ja) 2006-06-27 2009-12-17 オーラル ヘルス オーストラリア ピーティーワイ リミテッド 歯周病の予防に有用なポルフィロモナス・ジンジバリスポリペプチド
CN101842486A (zh) * 2007-07-12 2010-09-22 口腔健康澳洲私人有限公司 生物膜的免疫治疗
ES2432690T3 (es) * 2007-07-12 2013-12-04 Oral Health Australia Pty Ltd Tratamiento de biopelícula
US8142764B2 (en) 2008-02-27 2012-03-27 University Of Louisville Research Foundation Synthetic biofilm-inhibiting peptides
WO2010022463A1 (en) 2008-08-29 2010-03-04 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of p.gingivalis infection
US8140041B2 (en) * 2009-08-27 2012-03-20 Mediatek Inc. Tunable capacitive device with linearization technique employed therein
MY162557A (en) 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
BR112019005935A2 (pt) 2016-09-29 2019-06-11 Meharry Medical College inibidores bacterianos
CN113419059B (zh) * 2021-06-30 2023-09-01 迈克生物股份有限公司 用于化学发光免疫分析方法的封闭剂
WO2025019900A1 (en) * 2023-07-26 2025-01-30 Denteric Pty Ltd Chimeric protein vaccine

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210035A (en) 1980-05-19 1993-05-11 Board Of Trustees Of Leland Stanford Jr. University Non-reventing live vaccines
US4837151A (en) 1980-05-19 1989-06-06 The Board Of Trustees Of The Leland Stanford Junior University, Stanford University Live vaccines comprising two mutations and foreign antigen
US4735801A (en) 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
JPS60142915A (ja) * 1983-12-28 1985-07-29 Lion Corp 口腔用組成物
US4693888A (en) * 1983-08-11 1987-09-15 Lion Corporation Caries-preventive composition
AU557164B2 (en) * 1984-03-30 1986-12-11 Otsuka Kagaku Kabushiki Kaisha Preparation of fibrous alkali metal titanate
JPH0699291B2 (ja) * 1985-06-14 1994-12-07 ライオン株式会社 口腔用組成物
US5013542A (en) * 1988-02-08 1991-05-07 Forsyth Dental Infirmary For Children Method to inhibit adhesion of disease-causing microorganisms to teeth
IT8820888A0 (it) * 1988-06-08 1988-06-08 Eniricerche Spa Peptidi di sintesi immunologicamente attivi per lapreparazione di vaccini antimalarici.
US5830710A (en) 1988-09-08 1998-11-03 University Of Florida Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease
US5824791A (en) * 1988-09-08 1998-10-20 University Of Florida Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease
US5665559A (en) * 1989-05-18 1997-09-09 The United States Of America As Represented By The Secretary Of The Navy Production of monoclonal antibodies to bacteroides gingivalis by hybridoma BGII, VF9/2D
DE4324859A1 (de) * 1992-07-23 1994-01-27 Lion Corp Oral verabreichbare Zusammensetzung zur Behandlung periodontaler Erkrankungen
US5536497A (en) * 1992-12-21 1996-07-16 The Research Foundation Of State University Of New York Fimbrial polypeptides useful in the prevention of periodontitis
JPH08508240A (ja) * 1993-01-12 1996-09-03 ジョージ グリスティーナ,アンソニー 受動免疫の直接的濃厚伝達のための方法および組成物
WO1995000110A1 (en) * 1993-06-28 1995-01-05 Lion Corporation Composition for oral cavity
US6017532A (en) 1993-09-10 2000-01-25 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase
US5523390A (en) * 1993-09-10 1996-06-04 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase
EP0717747B1 (en) * 1993-09-10 2003-06-04 The University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase coding sequences
US5475097A (en) 1993-10-21 1995-12-12 University Of Georgia Research Foundation, Inc. Lysine-specific Porphyromonas gingivalis proteinase
JPH0797395A (ja) 1993-09-28 1995-04-11 Kyowa Medex Co Ltd ポルフイロモナス・ジンジバリス線毛蛋白質の配列を含有するペプチド類及びその用途
JPH09511220A (ja) * 1993-11-10 1997-11-11 ブリストル‐マイヤーズ スクイブ カンパニー バクテリアによって誘発される炎症性疾患の治療
EP0753577B1 (en) 1994-03-29 2002-07-24 Kyowa Hakko Kogyo Co., Ltd. Cell-surface polypeptide gene
FI98961C (fi) * 1994-08-26 1997-09-10 Medix Biochemica Ab Oy Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi
US20030157637A1 (en) * 1998-09-15 2003-08-21 The University Of Melbourne Diagnostics and treatments of periodontal disease
AUPN627595A0 (en) 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
US6129917A (en) * 1996-03-22 2000-10-10 The University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis
US7341727B1 (en) 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
AUPP083997A0 (en) 1997-12-10 1998-01-08 Csl Limited Porphyromonas gingivalis nucleotides
US8129500B2 (en) 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
US6444799B1 (en) 1997-12-31 2002-09-03 Csl Limited P. gingivalis polynucleotides and uses thereof
AUPP893999A0 (en) 1999-03-01 1999-03-25 Csl Limited Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis
US6833262B1 (en) * 1999-04-21 2004-12-21 University Of Georgia Research Foundation, Inc. Polypeptide having amidolytic activity for a serpin
CA2373447A1 (en) 1999-05-12 2000-11-16 The General Hospital Corporation Permeabilizing biofilms
GB9913437D0 (en) 1999-06-09 1999-08-11 Medical Res Council Fusion proteins
AUPQ485999A0 (en) 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
AUPQ718200A0 (en) 2000-04-28 2000-05-25 Csl Limited Porphyromonas gingivalis recombinant proteins and truncations
US20020110843A1 (en) * 2000-05-12 2002-08-15 Dumas David P. Compositions and methods for epitope mapping
AU2002225954A1 (en) * 2000-11-08 2002-05-21 The University Of Georgia Research Foundation, Inc. Dipeptidylpeptidases and methods of use
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US20030083287A1 (en) 2000-11-30 2003-05-01 Burgess Nicola A. ginS
US20020192206A1 (en) * 2001-05-05 2002-12-19 Kozarov Emil V. Methods and compositions for angioproliferative disorder treatment
AUPR575401A0 (en) 2001-06-18 2001-07-12 Unisearch Limited Method of causing sloughing
JP2003192616A (ja) 2001-12-27 2003-07-09 Univ Nihon 歯周病用dnaワクチン
JP2003286191A (ja) 2002-03-27 2003-10-07 Univ Nihon 歯周病用粘膜免疫ワクチン
US20070036734A1 (en) 2003-03-17 2007-02-15 Kirin Beer Kabushiki Kaisha Therapeutic agent for periodontal disease
DE602004031024D1 (de) 2003-08-15 2011-02-24 Univ Florida Die identifikation von polynukleotiden von porphyromonas gingivalis-virulenz zur diagnose, behandlung und beobachtung von periodontalerkrankungen
EP1721283B1 (en) 2004-02-06 2022-11-30 Council of Scientific and Industrial Research Computational method for identifying adhesin and adhesin-like proteins of therapeutic potential
US20070098649A1 (en) 2004-03-22 2007-05-03 The Board Of Trustees Of The University Of Illinois Method and composition for controlling oral pathogens
NZ554331A (en) 2004-09-23 2009-04-30 Univ Melbourne Antigenic complex for the diagnosis and treatment of porphyromonas gingivalis infection
WO2008016385A2 (en) 2006-01-20 2008-02-07 The University Of Washington Deacylase polypeptides, deacylase polynucleotides, and methods of use thereof
JP2009544279A (ja) 2006-06-27 2009-12-17 オーラル ヘルス オーストラリア ピーティーワイ リミテッド 歯周病の予防に有用なポルフィロモナス・ジンジバリスポリペプチド
WO2008124646A2 (en) 2007-04-06 2008-10-16 The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services Use of amyloid proteins as vaccine scaffolds
CN101842486A (zh) 2007-07-12 2010-09-22 口腔健康澳洲私人有限公司 生物膜的免疫治疗
ES2432690T3 (es) 2007-07-12 2013-12-04 Oral Health Australia Pty Ltd Tratamiento de biopelícula
KR100948094B1 (ko) 2007-12-26 2010-03-16 주식회사 하이닉스반도체 데이터 출력 제어회로
WO2010022463A1 (en) 2008-08-29 2010-03-04 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of p.gingivalis infection

Also Published As

Publication number Publication date
CA2639048A1 (en) 1998-11-05
US8431688B2 (en) 2013-04-30
EP1017714A4 (en) 2005-02-23
EP1985625B1 (en) 2014-11-12
EP1017714A1 (en) 2000-07-12
US20130309179A1 (en) 2013-11-21
DE69840027D1 (de) 2008-10-30
US20080124284A1 (en) 2008-05-29
CA2288234A1 (en) 1998-11-05
NZ500451A (en) 2001-02-23
EP2246361A1 (en) 2010-11-03
JP2002511847A (ja) 2002-04-16
EP1985625A2 (en) 2008-10-29
KR20010020417A (ko) 2001-03-15
US8841420B2 (en) 2014-09-23
US20110268670A1 (en) 2011-11-03
EP1985625A3 (en) 2009-02-18
CA2288234C (en) 2008-11-18
US20040005276A1 (en) 2004-01-08
US7749502B2 (en) 2010-07-06
CA2720332A1 (en) 1998-11-05
US7262271B2 (en) 2007-08-28
ATE408618T1 (de) 2008-10-15
DK1017714T3 (da) 2009-01-05
JP4276300B2 (ja) 2009-06-10
CA2720332C (en) 2013-07-23
CA2815903A1 (en) 1998-11-05
ES2530510T3 (es) 2015-03-03
CA2639048C (en) 2012-12-11
EP1017714B1 (en) 2008-09-17
WO1998049192A1 (en) 1998-11-05
AUPO652897A0 (en) 1997-05-29

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