ES2530510T3 - Constructos peptídicos sintéticos para el diagnóstico y tratamiento de periodontitis asociada con Porphyromonas gingivalis - Google Patents
Constructos peptídicos sintéticos para el diagnóstico y tratamiento de periodontitis asociada con Porphyromonas gingivalis Download PDFInfo
- Publication number
- ES2530510T3 ES2530510T3 ES08010103T ES08010103T ES2530510T3 ES 2530510 T3 ES2530510 T3 ES 2530510T3 ES 08010103 T ES08010103 T ES 08010103T ES 08010103 T ES08010103 T ES 08010103T ES 2530510 T3 ES2530510 T3 ES 2530510T3
- Authority
- ES
- Spain
- Prior art keywords
- porphyromonas gingivalis
- diagnosis
- treatment
- synthetic peptide
- peptide constructs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000605862 Porphyromonas gingivalis Species 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title 1
- 201000001245 periodontitis Diseases 0.000 title 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0216—Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Dental Preparations (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Una composición para uso para provocar una respuesta inmunitaria frente a Porphyromonas gingivalis, incluyendo la composición un adyuvante adecuado y/o vehículo o excipiente aceptable y al menos un péptido seleccionado del grupo que consiste en: PNGTPNPNPNPNPNPNPGTTTLSESF PNGTPNPNPNPNPNPGTTLSESF PNGTPNPNPNPNPGTTTLSESF PNGTPNPNPGTTTLSESF
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPO6528A AUPO652897A0 (en) | 1997-04-30 | 1997-04-30 | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2530510T3 true ES2530510T3 (es) | 2015-03-03 |
Family
ID=3800820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES08010103T Expired - Lifetime ES2530510T3 (es) | 1997-04-30 | 1998-04-30 | Constructos peptídicos sintéticos para el diagnóstico y tratamiento de periodontitis asociada con Porphyromonas gingivalis |
Country Status (12)
Country | Link |
---|---|
US (4) | US7262271B2 (es) |
EP (3) | EP1985625B1 (es) |
JP (1) | JP4276300B2 (es) |
KR (1) | KR100356040B1 (es) |
AT (1) | ATE408618T1 (es) |
AU (1) | AUPO652897A0 (es) |
CA (4) | CA2288234C (es) |
DE (1) | DE69840027D1 (es) |
DK (1) | DK1017714T3 (es) |
ES (1) | ES2530510T3 (es) |
NZ (1) | NZ500451A (es) |
WO (1) | WO1998049192A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPN627595A0 (en) * | 1995-10-30 | 1995-11-23 | University Of Melbourne, The | Diagnostics and treatments of periodontal disease |
AUPO652897A0 (en) | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
EP2264176A1 (en) * | 1997-12-10 | 2010-12-22 | CSL Limited | Porphorymonas gingivalis polypeptides and polynucleotides |
US8129500B2 (en) * | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
AUPP893999A0 (en) * | 1999-03-01 | 1999-03-25 | Csl Limited | Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis |
AUPQ485999A0 (en) * | 1999-12-24 | 2000-02-03 | Csl Limited | P. gingivalis antigenic composition |
US20070053923A1 (en) * | 2003-01-30 | 2007-03-08 | Ki-Seok Park | Dna vaccine composition with enhanced immunogenicity |
US20090169568A1 (en) | 2004-09-23 | 2009-07-02 | The University Of Melbourne | Antigenic Complex for the Diagnosis and Treatment of Porphyromonas Gingivalis Infection |
CA2652957A1 (en) | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
WO2009006699A1 (en) * | 2007-07-12 | 2009-01-15 | Oral Health Australia Pty Ltd | Biofilm treatment |
EP2176413A4 (en) | 2007-07-12 | 2012-08-01 | Oral Health Australia Pty Ltd | IMMUNOLOGY TREATMENT FOR BIOFILMS |
WO2009108716A2 (en) * | 2008-02-27 | 2009-09-03 | University Of Louisville Research Foundation | Synthetic peptides |
CN107266582B (zh) | 2008-08-29 | 2021-09-10 | 口腔健康澳洲私人有限公司 | 牙龈卟啉单胞菌感染的预防、治疗和诊断 |
US8140041B2 (en) * | 2009-08-27 | 2012-03-20 | Mediatek Inc. | Tunable capacitive device with linearization technique employed therein |
MY162557A (en) * | 2010-02-26 | 2017-06-15 | Oral Health Australia Pty Ltd | Treatment or prevention of infection |
MX2019003475A (es) * | 2016-09-29 | 2019-11-28 | Meharry Medical College | Inhibidores bacterianos. |
CN113419059B (zh) * | 2021-06-30 | 2023-09-01 | 迈克生物股份有限公司 | 用于化学发光免疫分析方法的封闭剂 |
Family Cites Families (60)
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US4837151A (en) | 1980-05-19 | 1989-06-06 | The Board Of Trustees Of The Leland Stanford Junior University, Stanford University | Live vaccines comprising two mutations and foreign antigen |
US5210035A (en) | 1980-05-19 | 1993-05-11 | Board Of Trustees Of Leland Stanford Jr. University | Non-reventing live vaccines |
US4735801A (en) | 1982-09-07 | 1988-04-05 | Board Of Trustees Of Leland Stanford Jr. University | Novel non-reverting salmonella live vaccines |
US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
JPS60142915A (ja) * | 1983-12-28 | 1985-07-29 | Lion Corp | 口腔用組成物 |
US4693888A (en) * | 1983-08-11 | 1987-09-15 | Lion Corporation | Caries-preventive composition |
AU557164B2 (en) * | 1984-03-30 | 1986-12-11 | Otsuka Kagaku Kabushiki Kaisha | Preparation of fibrous alkali metal titanate |
JPH0699291B2 (ja) * | 1985-06-14 | 1994-12-07 | ライオン株式会社 | 口腔用組成物 |
US5013542A (en) * | 1988-02-08 | 1991-05-07 | Forsyth Dental Infirmary For Children | Method to inhibit adhesion of disease-causing microorganisms to teeth |
IT8820888A0 (it) * | 1988-06-08 | 1988-06-08 | Eniricerche Spa | Peptidi di sintesi immunologicamente attivi per lapreparazione di vaccini antimalarici. |
US5824791A (en) * | 1988-09-08 | 1998-10-20 | University Of Florida | Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease |
US5830710A (en) * | 1988-09-08 | 1998-11-03 | University Of Florida | Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease |
US5665559A (en) * | 1989-05-18 | 1997-09-09 | The United States Of America As Represented By The Secretary Of The Navy | Production of monoclonal antibodies to bacteroides gingivalis by hybridoma BGII, VF9/2D |
DE4324859A1 (de) * | 1992-07-23 | 1994-01-27 | Lion Corp | Oral verabreichbare Zusammensetzung zur Behandlung periodontaler Erkrankungen |
US5536497A (en) * | 1992-12-21 | 1996-07-16 | The Research Foundation Of State University Of New York | Fimbrial polypeptides useful in the prevention of periodontitis |
CA2153661A1 (en) * | 1993-01-12 | 1994-07-21 | Anthony George Gristina | Methods and compositions for the direct concentrated delivery of passive immunity |
AU6983594A (en) * | 1993-06-28 | 1995-01-17 | Lion Corporation | Composition for oral cavity |
US6017532A (en) | 1993-09-10 | 2000-01-25 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
US5475097A (en) * | 1993-10-21 | 1995-12-12 | University Of Georgia Research Foundation, Inc. | Lysine-specific Porphyromonas gingivalis proteinase |
EP0717747B1 (en) * | 1993-09-10 | 2003-06-04 | The University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase coding sequences |
US5523390A (en) * | 1993-09-10 | 1996-06-04 | University Of Georgia Research Foundation, Inc. | Porphyromonas gingivalis arginine-specific proteinase |
JPH0797395A (ja) | 1993-09-28 | 1995-04-11 | Kyowa Medex Co Ltd | ポルフイロモナス・ジンジバリス線毛蛋白質の配列を含有するペプチド類及びその用途 |
US5840302A (en) * | 1993-11-10 | 1998-11-24 | Bristol-Myers Squibb Company | Treatment of bacterially-induced inflammatory diseases |
DE69527514T2 (de) | 1994-03-29 | 2003-04-03 | Kyowa Hakko Kogyo Co., Ltd. | Gen eines zelloberflächenpolypeptids |
FI98961C (fi) * | 1994-08-26 | 1997-09-10 | Medix Biochemica Ab Oy | Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi |
AUPN627595A0 (en) | 1995-10-30 | 1995-11-23 | University Of Melbourne, The | Diagnostics and treatments of periodontal disease |
US20030157637A1 (en) * | 1998-09-15 | 2003-08-21 | The University Of Melbourne | Diagnostics and treatments of periodontal disease |
EP0888124A4 (en) * | 1996-03-22 | 2001-04-11 | Univ Georgia Res Found | IMMUNOGENIC COMPOSITIONS COMPRISING PORPHYROMONAS GINGIVALIS PEPTIDES AND METHODS |
AUPN901296A0 (en) * | 1996-03-29 | 1996-04-26 | University Of Melbourne, The | Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis |
US7341727B1 (en) | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
AUPO652897A0 (en) | 1997-04-30 | 1997-05-29 | University Of Melbourne, The | Synthetic peptide constructs for the diagnosis and treatment of periodontitis |
AUPP083997A0 (en) | 1997-12-10 | 1998-01-08 | Csl Limited | Porphyromonas gingivalis nucleotides |
US8129500B2 (en) | 1997-12-10 | 2012-03-06 | Csl Limited | Porphyromonas gingivalis polypeptides and nucleotides |
US6444799B1 (en) | 1997-12-31 | 2002-09-03 | Csl Limited | P. gingivalis polynucleotides and uses thereof |
AUPP893999A0 (en) | 1999-03-01 | 1999-03-25 | Csl Limited | Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis |
US6833262B1 (en) * | 1999-04-21 | 2004-12-21 | University Of Georgia Research Foundation, Inc. | Polypeptide having amidolytic activity for a serpin |
JP2003534235A (ja) | 1999-05-12 | 2003-11-18 | ザ ゼネラル ホスピタル コーポレーション | バイオフイルムの透過性化 |
GB9913437D0 (en) | 1999-06-09 | 1999-08-11 | Medical Res Council | Fusion proteins |
AUPQ485999A0 (en) | 1999-12-24 | 2000-02-03 | Csl Limited | P. gingivalis antigenic composition |
AUPQ718200A0 (en) | 2000-04-28 | 2000-05-25 | Csl Limited | Porphyromonas gingivalis recombinant proteins and truncations |
US20020110843A1 (en) * | 2000-05-12 | 2002-08-15 | Dumas David P. | Compositions and methods for epitope mapping |
US6864363B2 (en) * | 2000-11-08 | 2005-03-08 | University Of Georgia Research Foundation, Inc. | Dipeptidylpeptidases and methods of use |
US6726898B2 (en) | 2000-11-17 | 2004-04-27 | Gary R. Jernberg | Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease |
US20030083287A1 (en) | 2000-11-30 | 2003-05-01 | Burgess Nicola A. | ginS |
US20020192206A1 (en) * | 2001-05-05 | 2002-12-19 | Kozarov Emil V. | Methods and compositions for angioproliferative disorder treatment |
AUPR575401A0 (en) | 2001-06-18 | 2001-07-12 | Unisearch Limited | Method of causing sloughing |
JP2003192616A (ja) | 2001-12-27 | 2003-07-09 | Univ Nihon | 歯周病用dnaワクチン |
JP2003286191A (ja) | 2002-03-27 | 2003-10-07 | Univ Nihon | 歯周病用粘膜免疫ワクチン |
US20070036734A1 (en) | 2003-03-17 | 2007-02-15 | Kirin Beer Kabushiki Kaisha | Therapeutic agent for periodontal disease |
WO2005019249A2 (en) | 2003-08-15 | 2005-03-03 | University Of Florida | Identification of porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases |
EP1721283B1 (en) | 2004-02-06 | 2022-11-30 | Council of Scientific and Industrial Research | Computational method for identifying adhesin and adhesin-like proteins of therapeutic potential |
US20070098649A1 (en) | 2004-03-22 | 2007-05-03 | The Board Of Trustees Of The University Of Illinois | Method and composition for controlling oral pathogens |
US20090169568A1 (en) | 2004-09-23 | 2009-07-02 | The University Of Melbourne | Antigenic Complex for the Diagnosis and Treatment of Porphyromonas Gingivalis Infection |
WO2008016385A2 (en) | 2006-01-20 | 2008-02-07 | The University Of Washington | Deacylase polypeptides, deacylase polynucleotides, and methods of use thereof |
CA2652957A1 (en) | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
WO2008124646A2 (en) | 2007-04-06 | 2008-10-16 | The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services | Use of amyloid proteins as vaccine scaffolds |
EP2176413A4 (en) | 2007-07-12 | 2012-08-01 | Oral Health Australia Pty Ltd | IMMUNOLOGY TREATMENT FOR BIOFILMS |
WO2009006699A1 (en) | 2007-07-12 | 2009-01-15 | Oral Health Australia Pty Ltd | Biofilm treatment |
KR100948094B1 (ko) | 2007-12-26 | 2010-03-16 | 주식회사 하이닉스반도체 | 데이터 출력 제어회로 |
CN107266582B (zh) | 2008-08-29 | 2021-09-10 | 口腔健康澳洲私人有限公司 | 牙龈卟啉单胞菌感染的预防、治疗和诊断 |
-
1997
- 1997-04-30 AU AUPO6528A patent/AUPO652897A0/en not_active Abandoned
-
1998
- 1998-04-30 AT AT98916667T patent/ATE408618T1/de not_active IP Right Cessation
- 1998-04-30 CA CA002288234A patent/CA2288234C/en not_active Expired - Fee Related
- 1998-04-30 WO PCT/AU1998/000311 patent/WO1998049192A1/en active IP Right Grant
- 1998-04-30 DK DK98916667T patent/DK1017714T3/da active
- 1998-04-30 NZ NZ500451A patent/NZ500451A/en not_active IP Right Cessation
- 1998-04-30 CA CA2720332A patent/CA2720332C/en not_active Expired - Fee Related
- 1998-04-30 DE DE69840027T patent/DE69840027D1/de not_active Expired - Lifetime
- 1998-04-30 EP EP08010103.3A patent/EP1985625B1/en not_active Expired - Lifetime
- 1998-04-30 ES ES08010103T patent/ES2530510T3/es not_active Expired - Lifetime
- 1998-04-30 EP EP98916667A patent/EP1017714B1/en not_active Expired - Lifetime
- 1998-04-30 KR KR1019997010041A patent/KR100356040B1/ko not_active IP Right Cessation
- 1998-04-30 JP JP54641598A patent/JP4276300B2/ja not_active Expired - Fee Related
- 1998-04-30 CA CA2639048A patent/CA2639048C/en not_active Expired - Fee Related
- 1998-04-30 EP EP10171207A patent/EP2246361A1/en not_active Withdrawn
- 1998-04-30 CA CA2815903A patent/CA2815903A1/en not_active Abandoned
-
2003
- 2003-03-12 US US10/387,977 patent/US7262271B2/en not_active Expired - Fee Related
-
2007
- 2007-03-30 US US11/731,307 patent/US7749502B2/en not_active Expired - Fee Related
-
2010
- 2010-06-09 US US12/797,566 patent/US8431688B2/en not_active Expired - Fee Related
-
2013
- 2013-03-28 US US13/852,272 patent/US8841420B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20040005276A1 (en) | 2004-01-08 |
CA2639048A1 (en) | 1998-11-05 |
JP4276300B2 (ja) | 2009-06-10 |
EP1017714A4 (en) | 2005-02-23 |
AUPO652897A0 (en) | 1997-05-29 |
EP1985625A3 (en) | 2009-02-18 |
EP2246361A1 (en) | 2010-11-03 |
CA2815903A1 (en) | 1998-11-05 |
US8431688B2 (en) | 2013-04-30 |
DE69840027D1 (de) | 2008-10-30 |
CA2720332C (en) | 2013-07-23 |
JP2002511847A (ja) | 2002-04-16 |
EP1017714A1 (en) | 2000-07-12 |
CA2639048C (en) | 2012-12-11 |
US20110268670A1 (en) | 2011-11-03 |
CA2720332A1 (en) | 1998-11-05 |
EP1985625B1 (en) | 2014-11-12 |
US7262271B2 (en) | 2007-08-28 |
US8841420B2 (en) | 2014-09-23 |
DK1017714T3 (da) | 2009-01-05 |
NZ500451A (en) | 2001-02-23 |
US7749502B2 (en) | 2010-07-06 |
US20130309179A1 (en) | 2013-11-21 |
KR100356040B1 (ko) | 2002-10-18 |
EP1985625A2 (en) | 2008-10-29 |
US20080124284A1 (en) | 2008-05-29 |
CA2288234A1 (en) | 1998-11-05 |
KR20010020417A (ko) | 2001-03-15 |
EP1017714B1 (en) | 2008-09-17 |
WO1998049192A1 (en) | 1998-11-05 |
CA2288234C (en) | 2008-11-18 |
ATE408618T1 (de) | 2008-10-15 |
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