KR100277621B1 - 신규한 의약 조성물 - Google Patents

신규한 의약 조성물 Download PDF

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Publication number
KR100277621B1
KR100277621B1 KR1019950700164A KR19950700164A KR100277621B1 KR 100277621 B1 KR100277621 B1 KR 100277621B1 KR 1019950700164 A KR1019950700164 A KR 1019950700164A KR 19950700164 A KR19950700164 A KR 19950700164A KR 100277621 B1 KR100277621 B1 KR 100277621B1
Authority
KR
South Korea
Prior art keywords
integer
caractopyranosyloxy
compound
caractosyl
ceramide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019950700164A
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English (en)
Korean (ko)
Other versions
KR950702431A (ko
Inventor
야스히코 고에주카
고지 가바야
가즈히로 모토키
Original Assignee
마나베 게이사꾸
기린비이루 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 마나베 게이사꾸, 기린비이루 가부시키가이샤 filed Critical 마나베 게이사꾸
Publication of KR950702431A publication Critical patent/KR950702431A/ko
Application granted granted Critical
Publication of KR100277621B1 publication Critical patent/KR100277621B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019950700164A 1992-07-16 1993-07-15 신규한 의약 조성물 Expired - Fee Related KR100277621B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP212015/1992 1992-07-16
JP21201592 1992-07-16
JP8521993 1993-03-19
JP85219/1993 1993-03-19
PCT/JP1993/000984 WO1994002168A1 (fr) 1992-07-16 1993-07-15 Nouvelle composition medicamenteuse

Publications (2)

Publication Number Publication Date
KR950702431A KR950702431A (ko) 1995-07-29
KR100277621B1 true KR100277621B1 (ko) 2001-02-01

Family

ID=26426239

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950700164A Expired - Fee Related KR100277621B1 (ko) 1992-07-16 1993-07-15 신규한 의약 조성물

Country Status (12)

Country Link
US (3) US5767092A (enExample)
EP (1) EP0650732B1 (enExample)
JP (1) JP3088461B2 (enExample)
KR (1) KR100277621B1 (enExample)
CN (1) CN1084623C (enExample)
AT (1) ATE200224T1 (enExample)
AU (1) AU684466B2 (enExample)
CA (1) CA2140013C (enExample)
DE (1) DE69330096T2 (enExample)
FI (1) FI950166A7 (enExample)
TW (1) TW261533B (enExample)
WO (1) WO1994002168A1 (enExample)

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JP2002226377A (ja) * 1996-10-14 2002-08-14 Kirin Brewery Co Ltd 配糖体含有末梢血幹細胞増加剤
TW555562B (en) * 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
ES2221147T3 (es) * 1997-02-05 2004-12-16 Kirin Beer Kabushiki Kaisha Composiciones liofilizadas conteniendo glicoesfingolipidos.
US6417167B1 (en) 1997-02-05 2002-07-09 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing shingoglycolipid and process for preparing them
CN1222293C (zh) 1997-04-10 2005-10-12 麒麟麦酒株式会社 含有α－糖基神经酰胺的NKT细胞活化剂
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
AU2001268564A1 (en) * 2000-06-22 2002-01-02 The Brigham And Women's Hospital, Inc. Alpha-glycosylceramides for treating bacterial and fungal infections
AU2002327338A1 (en) * 2001-07-25 2003-02-17 New York University Use of glycosylceramides as adjuvants for vaccines against infections and cancer
HU229345B1 (en) * 2001-08-16 2013-11-28 Japan Government Novel glycolipid and remedial agent for autoimmune disease containing the same as active ingredient
US8443383B2 (en) * 2002-05-03 2013-05-14 Time Warner Cable Enterprises Llc Use of messages in program signal streams by set-top terminals
KR20050062551A (ko) * 2002-09-20 2005-06-23 기린 비루 가부시키가이샤 α-글리코실세라미드를 유효 성분으로 하는 Ｃ형 간염 바이러스 억제제
US7645873B2 (en) 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
CA2519568C (en) * 2003-03-20 2012-01-03 Brigham Young University 6"-amino-6"-deoxygalactosylceramides
US7309015B2 (en) * 2004-07-14 2007-12-18 Scanbuy, Inc. Mobile device gateway providing access to instant information
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
CN101080487B (zh) 2004-10-07 2012-11-14 阿戈斯治疗公司 成熟树突细胞组合物及其培养方法
WO2006071848A2 (en) * 2004-12-28 2006-07-06 The Rockefeller University Glycolipids and analogues thereof as antigens for nk t cells
US7923013B2 (en) * 2004-12-28 2011-04-12 The Rockefeller University Glycolipids and analogues thereof as antigens for NKT cells
WO2006083671A2 (en) 2005-01-28 2006-08-10 Brigham Young University Bacterial glycolipid activation of cd1d-restricted nkt cells
WO2006096500A2 (en) * 2005-03-04 2006-09-14 The Regents Of The University Of California Highly efficient synthesis of alpha-o-galactosyl ceramides
BRPI0612732A2 (pt) * 2005-07-01 2011-08-16 Japan As Represented By The President Of Nat Ct Of Neurology And Psychiatry derivado de glicolipìdeo e uso do mesmo
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
US20070231344A1 (en) * 2005-10-28 2007-10-04 The Brigham And Women's Hospital, Inc. Conjugate vaccines for non-proteinaceous antigens
SI2056842T1 (sl) * 2006-04-07 2013-02-28 The Scripps Research Institute Modificiran galaktosil-ceramid za zdravljenje kancerogenih obolenj
AU2007269299B2 (en) * 2006-06-30 2013-01-17 Brigham Young University Adjuvants and methods of use
US8263576B2 (en) * 2006-08-15 2012-09-11 Mayo Foundation For Medical Education And Research Non-natural sphingolipid analogs and uses thereof
US8916164B2 (en) * 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
WO2009060305A2 (en) * 2007-10-12 2009-05-14 Luigi Panza Analogues of glycolipids useful as immunoadjuvants
EP2058011A1 (en) * 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
WO2009101475A2 (en) * 2007-12-05 2009-08-20 Wittycell S.A.S. Compositions for and methods of enhancing the immune response to antigens
CN102215864A (zh) * 2008-10-08 2011-10-12 威蒂赛尔公司 用于抗流感的疫苗组合物
EP2396017B1 (en) 2009-02-16 2015-07-01 Cerenis Therapeutics Holding SA Apolipoprotein a-i mimics
ES2646835T3 (es) 2010-10-18 2017-12-18 Cerenis Therapeutics Holding Sa Compuestos, composiciones y procedimientos útiles para la movilización del colesterol
EP2647384B1 (en) 2010-12-02 2018-05-23 Riken IMMUNOTHERAPY USING ALLO-NKT CELLS, CELLS FOR IMMUNOTHERAPY IN WHICH alpha CHAIN OF T-CELL RECEPTOR (TCR) GENE HAS BEEN REARRANGED TO UNIFORM V alpha-J alpha , AND BANKING OF NKT CELLS DERIVED FROM SAID CELLS
US10227290B2 (en) 2012-02-07 2019-03-12 The Regents Of The University Of California Glycosphingolipids for use in modulating immune responses
AU2013306767A1 (en) 2012-08-22 2015-03-12 Regimmune Corporation Preparation for preventing or treating type I diabetes
US10329315B2 (en) 2012-10-12 2019-06-25 The Brigham And Women's Hospital, Inc. Glycosphingolipids and methods of use thereof
KR20150106872A (ko) 2012-11-05 2015-09-22 가부시키가이샤 레그이뮨 면역 관용 유도제
US10151745B2 (en) 2012-11-21 2018-12-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for determining the risk of acute graft versus host disease
JP2015205835A (ja) * 2014-04-21 2015-11-19 国立大学法人福井大学 中性子線障害防護剤
AU2021392472A1 (en) 2020-12-04 2023-07-06 Osaka University Cd1d-ligand-compound-containing liposome preparation having improved pharmacokinetics

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JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
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Also Published As

Publication number Publication date
FI950166A0 (fi) 1995-01-13
HK1009937A1 (en) 1999-09-17
WO1994002168A1 (fr) 1994-02-03
CN1088093A (zh) 1994-06-22
CA2140013C (en) 2002-08-27
EP0650732A1 (en) 1995-05-03
AU4583593A (en) 1994-02-14
CN1084623C (zh) 2002-05-15
US6017892A (en) 2000-01-25
FI950166A7 (fi) 1995-01-31
US5767092A (en) 1998-06-16
AU684466B2 (en) 1997-12-18
KR950702431A (ko) 1995-07-29
DE69330096D1 (de) 2001-05-10
TW261533B (enExample) 1995-11-01
CA2140013A1 (en) 1994-02-03
US6071884A (en) 2000-06-06
EP0650732A4 (en) 1998-04-01
ATE200224T1 (de) 2001-04-15
EP0650732B1 (en) 2001-04-04
JP3088461B2 (ja) 2000-09-18
DE69330096T2 (de) 2001-10-18

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