DE69330096D1 - Neue medizinische zusammensetzung - Google Patents

Neue medizinische zusammensetzung

Info

Publication number
DE69330096D1
DE69330096D1 DE69330096T DE69330096T DE69330096D1 DE 69330096 D1 DE69330096 D1 DE 69330096D1 DE 69330096 T DE69330096 T DE 69330096T DE 69330096 T DE69330096 T DE 69330096T DE 69330096 D1 DE69330096 D1 DE 69330096D1
Authority
DE
Germany
Prior art keywords
ych3
medical composition
new medical
integer
ych
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69330096T
Other languages
English (en)
Other versions
DE69330096T2 (de
DE601962T1 (de
Inventor
Yasuhiko Koezuka
Koji Kabaya
Kazuhiro Motoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kirin Brewery Co Ltd
Original Assignee
Kirin Brewery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery Co Ltd filed Critical Kirin Brewery Co Ltd
Application granted granted Critical
Publication of DE69330096D1 publication Critical patent/DE69330096D1/de
Publication of DE69330096T2 publication Critical patent/DE69330096T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
DE69330096T 1992-07-16 1993-07-15 Neue medizinische zusammensetzung Expired - Fee Related DE69330096T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21201592 1992-07-16
JP8521993 1993-03-19
PCT/JP1993/000984 WO1994002168A1 (en) 1992-07-16 1993-07-15 Novel medicinal composition

Publications (2)

Publication Number Publication Date
DE69330096D1 true DE69330096D1 (de) 2001-05-10
DE69330096T2 DE69330096T2 (de) 2001-10-18

Family

ID=26426239

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69330096T Expired - Fee Related DE69330096T2 (de) 1992-07-16 1993-07-15 Neue medizinische zusammensetzung

Country Status (13)

Country Link
US (3) US5767092A (de)
EP (1) EP0650732B1 (de)
JP (1) JP3088461B2 (de)
KR (1) KR100277621B1 (de)
CN (1) CN1084623C (de)
AT (1) ATE200224T1 (de)
AU (1) AU684466B2 (de)
CA (1) CA2140013C (de)
DE (1) DE69330096T2 (de)
FI (1) FI950166A (de)
HK (1) HK1009937A1 (de)
TW (1) TW261533B (de)
WO (1) WO1994002168A1 (de)

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DE69328435T2 (de) * 1992-10-22 2000-09-14 Kirin Brewery Neues sphingolglycolipid und verwendung davon
EP0694558B1 (de) * 1993-04-15 1999-01-27 Kirin Beer Kabushiki Kaisha Sphingoglycolipid und verwendung davon
US6026815A (en) * 1996-10-10 2000-02-22 Gholam A. Peyman Radiopaque liquid as radiation blocking agent
JP2002226377A (ja) * 1996-10-14 2002-08-14 Kirin Brewery Co Ltd 配糖体含有末梢血幹細胞増加剤
TW555562B (en) * 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
US6417167B1 (en) 1997-02-05 2002-07-09 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing shingoglycolipid and process for preparing them
WO1998034623A1 (fr) * 1997-02-05 1998-08-13 Kirin Beer Kabushiki Kaisha Composition lyophylisee a base de glycosphingolipide et procede de fabrication
EP0988860B1 (de) * 1997-04-10 2005-01-12 Kirin Beer Kabushiki Kaisha Verwendung von a-Glycosylceramiden zur Herstellung eines therapeutischen Mittelszur Behandlung von Autoimmunkrankheiten
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
AU2001268564A1 (en) * 2000-06-22 2002-01-02 The Brigham And Women's Hospital, Inc. Alpha-glycosylceramides for treating bacterial and fungal infections
CA2453880A1 (en) * 2001-07-25 2003-02-06 New York University Use of glycosylceramides as adjuvants for vaccines against infections and cancer
US8367623B2 (en) * 2001-08-16 2013-02-05 Japan As Represented By President Of National Center Of Neurology And Psychiatry Glycolipid and medicine for autoimmune disease containing the same as active ingredient
US8443383B2 (en) * 2002-05-03 2013-05-14 Time Warner Cable Enterprises Llc Use of messages in program signal streams by set-top terminals
BR0314640A (pt) * 2002-09-20 2005-08-02 Kirin Brewery Inibidor de vìrus de hepatite c compreendendo, como um ingrediente ativo, alfa-glicosilceramida
US7645873B2 (en) 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
WO2004094444A1 (en) * 2003-03-20 2004-11-04 Brigham Young University 6'-amino-6'-deoxygalactosylceramides
US7309015B2 (en) * 2004-07-14 2007-12-18 Scanbuy, Inc. Mobile device gateway providing access to instant information
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
KR101243577B1 (ko) 2004-10-07 2013-03-20 아고스 쎄라퓨틱스, 인코포레이티드 성숙 수지상 세포 조성물 및 그의 배양 방법
US7923013B2 (en) * 2004-12-28 2011-04-12 The Rockefeller University Glycolipids and analogues thereof as antigens for NKT cells
EP1833489A4 (de) * 2004-12-28 2011-08-03 Univ Rockefeller Glykolipide und analoga davon als antigene für nk-t-zellen
PT1848813E (pt) 2005-01-28 2013-07-15 Scripps Research Inst Activação de glicolípidos bacterianos de células nkt restritas ao cd1d
US20090036658A1 (en) * 2005-03-04 2009-02-05 The Regents Of The University Of California Highly efficient synthesis of alpha-O-galactosyl ceramides
BRPI0612732A2 (pt) * 2005-07-01 2011-08-16 Japan As Represented By The President Of Nat Ct Of Neurology And Psychiatry derivado de glicolipìdeo e uso do mesmo
EP1776963A1 (de) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramiden als Adjuvantien und ihre Verwendung in pharmazeutischen Zusammensetzungen
US20070231344A1 (en) * 2005-10-28 2007-10-04 The Brigham And Women's Hospital, Inc. Conjugate vaccines for non-proteinaceous antigens
CA2661789C (en) * 2006-04-07 2014-06-03 The Scripps Research Institute Modified .alpha.-galactosyl ceramides for staining and stimulating natural killer t cells
JP5564672B2 (ja) * 2006-06-30 2014-07-30 ザ スクリプス リサーチ インスティテュート アジュバント及びその使用方法
US8263576B2 (en) * 2006-08-15 2012-09-11 Mayo Foundation For Medical Education And Research Non-natural sphingolipid analogs and uses thereof
US8916164B2 (en) * 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
US8697659B2 (en) * 2007-10-12 2014-04-15 Luigi Panza Analogues of glycolipids useful as immunoadjuvants
EP2058011A1 (de) * 2007-11-07 2009-05-13 Wittycell NKT-Zellen aktivierende, kovalent gebundene Glykolipid-Antigene und/oder Arzneimittel
WO2009101475A2 (en) * 2007-12-05 2009-08-20 Wittycell S.A.S. Compositions for and methods of enhancing the immune response to antigens
MX338827B (es) * 2008-10-08 2016-05-03 Vincent Serra Composicion de vacuna para uso contra influenza.
SI2396017T1 (sl) 2009-02-16 2015-12-31 Cerenis Therapeutics Holding Sa Mimika apolipoproteina A-1
PT2629776T (pt) 2010-10-18 2017-11-15 Cerenis Therapeutics Holding Sa Compostos, composições e métodos úteis para a mobilização de colesterol
ES2675582T3 (es) 2010-12-02 2018-07-11 Riken Inmunoterapia utilizando células alo-NKT, células para inmunoterapia en las que la cadena alfa del gen del receptor de las células T (TCR) ha sido redistribuida a V alfa-J alfa uniforme, y banco de células NKT derivadas de dichas células
US10227290B2 (en) 2012-02-07 2019-03-12 The Regents Of The University Of California Glycosphingolipids for use in modulating immune responses
CA2882553A1 (en) 2012-08-22 2013-08-22 Regimmune Corporation Preparation for preventing or treating type i diabetes
EP2906576B1 (de) 2012-10-12 2019-09-11 The Brigham and Women's Hospital, Inc. Glycosphingolipide und verfahren zur verwendung davon
CN105120877A (zh) 2012-11-05 2015-12-02 株式会社雷吉姆恩 免疫耐受诱导物
WO2014079946A1 (en) 2012-11-21 2014-05-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for determining the risk of acute graft versus host disease
JP2015205835A (ja) * 2014-04-21 2015-11-19 国立大学法人福井大学 中性子線障害防護剤
AU2021392472A1 (en) 2020-12-04 2023-07-06 Osaka University Cd1d-ligand-compound-containing liposome preparation having improved pharmacokinetics

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US3622666A (en) * 1968-03-04 1971-11-23 Stanley Drug Products Inc Methods for treating bacterial infections with phrenosin
US4598051A (en) * 1980-03-12 1986-07-01 The Regents Of The University Of California Liposome conjugates and diagnostic methods therewith
US4806466A (en) * 1981-10-29 1989-02-21 The Regents Of The University Of California Cell agglutination reagent comprising conjugates of antibody covalently bound to liposomes
IT1168205B (it) * 1983-07-21 1987-05-20 Wellcome Italia Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione
EP0146810A3 (de) * 1983-12-05 1987-05-13 Solco Basel AG Verfahren zur Herstellung von Sphingosinderivaten
JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
JPS6239597A (ja) * 1985-08-13 1987-02-20 ソルコ　バ−ゼル　アクチエンゲゼルシヤフト スフインゴシン誘導体の製造方法
JPH07116209B2 (ja) * 1986-04-11 1995-12-13 メクト株式会社 シアロシルセラミド類及びその製造方法
US4990603A (en) * 1986-07-04 1991-02-05 Mect Corporation Sialic acid derivatives and process therefor
US4937232A (en) * 1986-09-15 1990-06-26 Duke University Inhibition of protein kinase C by long-chain bases
US4816450A (en) * 1986-09-15 1989-03-28 Duke University Inhibition of protein kinase C by long-chain bases
JPS6495A (en) * 1986-12-19 1989-01-05 Tosoh Corp Alpha-glycosyl ceramide derivative
US5026557A (en) * 1987-09-09 1991-06-25 The Liposome Company, Inc. Adjuvant composition
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
US5041441A (en) * 1988-04-04 1991-08-20 The Regents Of The University Of Michigan Method of chemotherapy using 1-phenyl-2-decanoylamino-3-morpholino-1-propanol
US5073543A (en) * 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
JP2631532B2 (ja) * 1988-10-14 1997-07-16 富士写真フイルム株式会社 熱転写受像材料
DE3840044A1 (de) * 1988-11-27 1990-06-07 Behringwerke Ag Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung
IT1235162B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisosfingolipidi
US5028715A (en) * 1989-02-06 1991-07-02 Southwest Research Institute Radioprotective agents and their method of manufacture
US5210073A (en) * 1989-09-29 1993-05-11 Ajinomoto Co., Inc. Method for treating cancer therapy radiation damage or arteriosclerosis using human adf
JP3068910B2 (ja) * 1990-11-08 2000-07-24 麒麟麦酒株式会社 新規スフィンゴ糖脂質、その製造法および使用
JPH06145189A (ja) * 1991-01-23 1994-05-24 Kitasato Inst:The スフィンゴ糖脂質
JP3034650B2 (ja) * 1991-06-19 2000-04-17 株式会社ジーシー 歯質用接着剤
JPH0559081A (ja) * 1991-08-29 1993-03-09 Kirin Brewery Co Ltd 新規スフインゴ糖脂質、その製造法および使用
EP0694558B1 (de) * 1993-04-15 1999-01-27 Kirin Beer Kabushiki Kaisha Sphingoglycolipid und verwendung davon

Also Published As

Publication number Publication date
WO1994002168A1 (en) 1994-02-03
DE69330096T2 (de) 2001-10-18
EP0650732A1 (de) 1995-05-03
CN1084623C (zh) 2002-05-15
AU684466B2 (en) 1997-12-18
KR100277621B1 (ko) 2001-02-01
CA2140013A1 (en) 1994-02-03
EP0650732B1 (de) 2001-04-04
KR950702431A (ko) 1995-07-29
FI950166A0 (fi) 1995-01-13
HK1009937A1 (en) 1999-09-17
US5767092A (en) 1998-06-16
FI950166A (fi) 1995-01-31
TW261533B (de) 1995-11-01
US6017892A (en) 2000-01-25
US6071884A (en) 2000-06-06
CN1088093A (zh) 1994-06-22
CA2140013C (en) 2002-08-27
ATE200224T1 (de) 2001-04-15
AU4583593A (en) 1994-02-14
JP3088461B2 (ja) 2000-09-18
EP0650732A4 (de) 1998-04-01

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee