JPS6495A - Alpha-glycosyl ceramide derivative - Google Patents

Alpha-glycosyl ceramide derivative

Info

Publication number
JPS6495A
JPS6495A JP62295152A JP29515287A JPS6495A JP S6495 A JPS6495 A JP S6495A JP 62295152 A JP62295152 A JP 62295152A JP 29515287 A JP29515287 A JP 29515287A JP S6495 A JPS6495 A JP S6495A
Authority
JP
Japan
Prior art keywords
group
alpha
ceramide derivative
azido
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62295152A
Other languages
Japanese (ja)
Other versions
JPH0195A (en
Inventor
Koichi Nakano
Hironobu Hashimoto
Reiji Kanaki
Takao Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tosoh Corp
Original Assignee
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tosoh Corp filed Critical Tosoh Corp
Priority to JP62-295152A priority Critical patent/JPH0195A/en
Priority claimed from JP62-295152A external-priority patent/JPH0195A/en
Publication of JPS6495A publication Critical patent/JPS6495A/en
Publication of JPH0195A publication Critical patent/JPH0195A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by formula I [one of R1 and R2 is H and the other is OH; one of R3 and R4 is H and the other is OH or hexapyranosyl of (1→4) bond; X1 and X2 are H or bonded to form double bond; n is 10W25].
EXAMPLE: 2-Azido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl 1-1(3-O-benzoyl) ceramide.
USE: An antigen for sensitization.
PREPARATION: Triphenylphosphine is added to azide part of an α-(2-azido-2- deoxyhexopyranosyl) ceramide derivative shown by formula II (one of R1 and R2 is H and the other is lower acyloxy; R6 is lower acyl; R7 is OH-protecting group), the resultant compound is hydrolyzed to convert the azide group to an amino group, the amino group is acetylated, the protecting group R7 is eliminated and the lower acyloxy group is converted into OH.
COPYRIGHT: (C)1989,JPO&Japio
JP62-295152A 1986-12-19 1987-11-25 α-glycosylceramide derivative Pending JPH0195A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62-295152A JPH0195A (en) 1986-12-19 1987-11-25 α-glycosylceramide derivative

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP61-310178 1986-12-19
JP31017886 1986-12-19
JP62-26342 1987-02-09
JP62-295152A JPH0195A (en) 1986-12-19 1987-11-25 α-glycosylceramide derivative

Publications (2)

Publication Number Publication Date
JPS6495A true JPS6495A (en) 1989-01-05
JPH0195A JPH0195A (en) 1989-01-05

Family

ID=

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576640A (en) * 1983-07-02 1986-03-18 Lucas Industries Public Limited Company Hydrogen storage material
WO1994009020A1 (en) * 1992-10-22 1994-04-28 Kirin Beer Kabushiki Kaisha Novel shingoglycolipid and use thereof
US5780441A (en) * 1993-04-15 1998-07-14 Kirin Beer Kabushiki Kaisha Sphingoglycolipid compounds and therapeutic uses thereof
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
US6017892A (en) * 1992-07-16 2000-01-25 Kiran Beer Kabushiki Kaisha Method for accelerating marrow cell proliferation

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576640A (en) * 1983-07-02 1986-03-18 Lucas Industries Public Limited Company Hydrogen storage material
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
US6017892A (en) * 1992-07-16 2000-01-25 Kiran Beer Kabushiki Kaisha Method for accelerating marrow cell proliferation
US6071884A (en) * 1992-07-16 2000-06-06 Kirin Beer Kabushiki Kaisha Pharmaceutical compositions and therapeutic methods
WO1994009020A1 (en) * 1992-10-22 1994-04-28 Kirin Beer Kabushiki Kaisha Novel shingoglycolipid and use thereof
US5849716A (en) * 1992-10-22 1998-12-15 Kirin Beer Kabushiki Kaisha Sphingoglycolipids, their preparation, and therapeutic methods of use
KR100281264B1 (en) * 1992-10-22 2001-02-01 마나배 게이사꾸 New Spinosaccharide Lipids and Their Uses
US5780441A (en) * 1993-04-15 1998-07-14 Kirin Beer Kabushiki Kaisha Sphingoglycolipid compounds and therapeutic uses thereof

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