JPS6431752A - Amide derivative and skin external preparation containing said derivative - Google Patents
Amide derivative and skin external preparation containing said derivativeInfo
- Publication number
- JPS6431752A JPS6431752A JP18723487A JP18723487A JPS6431752A JP S6431752 A JPS6431752 A JP S6431752A JP 18723487 A JP18723487 A JP 18723487A JP 18723487 A JP18723487 A JP 18723487A JP S6431752 A JPS6431752 A JP S6431752A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- derivative
- hydrocarbon group
- external preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound shown by formula I (R<1> is 10-26C hydrocarbon group; R<2> is 9-25C hydrocarbon group; X and Y are H, 1-4C hydrocarbon group, acryl or aralkyl and are not H at the same time). EXAMPLE:N-(3-Hexadesyloxy-2-hydroxypropyl)-N-2-methylethylhexadecanamide. USE:A skin external preparation showing excellent improving and preventing effects chapped skin. PREPARATION:Amino group of a compound shown by formula II obtained from glycidyl ether and an ethanolamine derivative according to the reaction formula is selectively acylated to give a compound shown by formula III. Hydroxyl group of the compound shown by formula III is reacted with an alkyl halide such as methyl iodine in the presence of a basic catalyst (e.g. pyridine) to give a compound shown by formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62187234A JPH078844B2 (en) | 1987-07-27 | 1987-07-27 | Amide derivative and external preparation for skin containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62187234A JPH078844B2 (en) | 1987-07-27 | 1987-07-27 | Amide derivative and external preparation for skin containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6431752A true JPS6431752A (en) | 1989-02-02 |
JPH078844B2 JPH078844B2 (en) | 1995-02-01 |
Family
ID=16202404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62187234A Expired - Fee Related JPH078844B2 (en) | 1987-07-27 | 1987-07-27 | Amide derivative and external preparation for skin containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH078844B2 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5446027A (en) * | 1992-11-02 | 1995-08-29 | Kao Corporation | Amide derivative and external skin care preparation containing the same |
JPH09165313A (en) * | 1995-12-15 | 1997-06-24 | Kao Corp | Skin preparation for external use |
US6468251B1 (en) | 1997-10-23 | 2002-10-22 | Jims Co., Ltd. | Mixing/charging port for medical treatment |
WO2018221602A1 (en) | 2017-05-30 | 2018-12-06 | 花王株式会社 | Water-in-oil emulsion composition |
WO2018221603A1 (en) | 2017-05-30 | 2018-12-06 | 花王株式会社 | Water-in-oil emulsion composition |
WO2019131987A1 (en) | 2017-12-28 | 2019-07-04 | 花王株式会社 | Lipid particle dispersion |
WO2023095810A1 (en) | 2021-11-26 | 2023-06-01 | 花王株式会社 | Emulsion composition |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62215553A (en) * | 1986-03-18 | 1987-09-22 | Kao Corp | Glycerol derivative and pharmaceutical preparation containing same |
JPS63218609A (en) * | 1987-03-09 | 1988-09-12 | Kao Corp | External drug for skin |
JPS63227514A (en) * | 1987-03-16 | 1988-09-21 | Kao Corp | Dermatic drug for external application |
JPS63227513A (en) * | 1987-03-16 | 1988-09-21 | Kao Corp | Dermatic drug for external application |
JPS6429347A (en) * | 1987-07-24 | 1989-01-31 | Kao Corp | Amide derivative and external agent for skin containing said derivative |
-
1987
- 1987-07-27 JP JP62187234A patent/JPH078844B2/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62215553A (en) * | 1986-03-18 | 1987-09-22 | Kao Corp | Glycerol derivative and pharmaceutical preparation containing same |
JPS63218609A (en) * | 1987-03-09 | 1988-09-12 | Kao Corp | External drug for skin |
JPS63227514A (en) * | 1987-03-16 | 1988-09-21 | Kao Corp | Dermatic drug for external application |
JPS63227513A (en) * | 1987-03-16 | 1988-09-21 | Kao Corp | Dermatic drug for external application |
JPS6429347A (en) * | 1987-07-24 | 1989-01-31 | Kao Corp | Amide derivative and external agent for skin containing said derivative |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5446027A (en) * | 1992-11-02 | 1995-08-29 | Kao Corporation | Amide derivative and external skin care preparation containing the same |
JPH09165313A (en) * | 1995-12-15 | 1997-06-24 | Kao Corp | Skin preparation for external use |
US6468251B1 (en) | 1997-10-23 | 2002-10-22 | Jims Co., Ltd. | Mixing/charging port for medical treatment |
WO2018221602A1 (en) | 2017-05-30 | 2018-12-06 | 花王株式会社 | Water-in-oil emulsion composition |
WO2018221603A1 (en) | 2017-05-30 | 2018-12-06 | 花王株式会社 | Water-in-oil emulsion composition |
WO2019131987A1 (en) | 2017-12-28 | 2019-07-04 | 花王株式会社 | Lipid particle dispersion |
WO2023095810A1 (en) | 2021-11-26 | 2023-06-01 | 花王株式会社 | Emulsion composition |
Also Published As
Publication number | Publication date |
---|---|
JPH078844B2 (en) | 1995-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |