JPS55108889A - 4-o-methylaclacinomycin a and its preparation - Google Patents
4-o-methylaclacinomycin a and its preparationInfo
- Publication number
- JPS55108889A JPS55108889A JP1638079A JP1638079A JPS55108889A JP S55108889 A JPS55108889 A JP S55108889A JP 1638079 A JP1638079 A JP 1638079A JP 1638079 A JP1638079 A JP 1638079A JP S55108889 A JPS55108889 A JP S55108889A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- methylaclacinomycin
- preparation
- aclacinomycin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:4-O-Methylaclacinomycin A of formula I and its acid adducts.
USE: Antitumorigenic agent; for example, they remarkably prohibit the proliferation of cultured cells of mouse leukemia (L1210) and synthesis of nucleic acids.
PREPARATION: The selective methylation of the hydroxyl group in the 4-position of the compound of formula II or its acid adduct to give the compound of formula I. Aclacinomycin A of formula II is a compound invented by Umezawa, et al (cf, J.P laid-open No.51-34915) and produced by the fermentation of Streptomyces MAI 44-MI (FERM-2455).
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1638079A JPS55108889A (en) | 1979-02-15 | 1979-02-15 | 4-o-methylaclacinomycin a and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1638079A JPS55108889A (en) | 1979-02-15 | 1979-02-15 | 4-o-methylaclacinomycin a and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55108889A true JPS55108889A (en) | 1980-08-21 |
Family
ID=11914667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1638079A Pending JPS55108889A (en) | 1979-02-15 | 1979-02-15 | 4-o-methylaclacinomycin a and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55108889A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4418192A (en) * | 1981-04-23 | 1983-11-29 | Sanraku-Ocean Co., Ltd. | Anthracyclinone trisaccharide compounds |
-
1979
- 1979-02-15 JP JP1638079A patent/JPS55108889A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4418192A (en) * | 1981-04-23 | 1983-11-29 | Sanraku-Ocean Co., Ltd. | Anthracyclinone trisaccharide compounds |
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