JPS53130693A - Antibiotic substance c-15003 - Google Patents

Antibiotic substance c-15003

Info

Publication number
JPS53130693A
JPS53130693A JP3716677A JP3716677A JPS53130693A JP S53130693 A JPS53130693 A JP S53130693A JP 3716677 A JP3716677 A JP 3716677A JP 3716677 A JP3716677 A JP 3716677A JP S53130693 A JPS53130693 A JP S53130693A
Authority
JP
Japan
Prior art keywords
antibiotic substance
antibiotic
substance
substances
called
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3716677A
Other languages
Japanese (ja)
Other versions
JPS6034556B2 (en
Inventor
Eiji Higashide
Mitsuko Asai
Seiichi Tanida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP52037166A priority Critical patent/JPS6034556B2/en
Priority to US05/811,448 priority patent/US4162940A/en
Priority to AU29074/77A priority patent/AU510499B2/en
Priority to AU29072/77A priority patent/AU506415B2/en
Priority to PH20297A priority patent/PH13381A/en
Priority to FR7730339A priority patent/FR2385714A1/en
Priority to SU772529301A priority patent/SU741804A3/en
Priority to GR54548A priority patent/GR66051B/el
Priority to YU02453/77A priority patent/YU245377A/en
Priority to CS776678A priority patent/CS214749B2/en
Priority to NLAANVRAGE7711274,A priority patent/NL188102C/en
Priority to SE7711542A priority patent/SE442873B/en
Priority to NL7711272A priority patent/NL7711272A/en
Priority to HU802440A priority patent/HU187372B/en
Priority to HU77TA1459A priority patent/HU178359B/en
Priority to AT0736277A priority patent/AT364081B/en
Priority to IE2101/77A priority patent/IE46064B1/en
Priority to DE19772746252 priority patent/DE2746252A1/en
Priority to ES463207A priority patent/ES463207A1/en
Priority to CA288,731A priority patent/CA1107212A/en
Priority to DK458877A priority patent/DK458877A/en
Priority to GB42823/77A priority patent/GB1592264A/en
Priority to GB42822/77A priority patent/GB1586688A/en
Priority to DE19772746209 priority patent/DE2746209A1/en
Priority to PL1977221358A priority patent/PL124349B1/en
Priority to PL1977201541A priority patent/PL122289B1/en
Priority to CH1260577A priority patent/CH637137A5/en
Priority to IT21818/78A priority patent/IT1094308B/en
Priority to IT21817/78A priority patent/IT1094020B/en
Priority to PT67854A priority patent/PT67854B/en
Priority to BE186487A priority patent/BE865590A/en
Priority to ZA00781863A priority patent/ZA781863B/en
Priority to ZA00781862A priority patent/ZA781862B/en
Priority to BE186486A priority patent/BE865589A/en
Priority to SU782627804A priority patent/SU890978A3/en
Priority to ES472230A priority patent/ES472230A1/en
Publication of JPS53130693A publication Critical patent/JPS53130693A/en
Priority to AT822678A priority patent/AT362061B/en
Priority to US05/972,492 priority patent/US4225494A/en
Priority to PH22216A priority patent/PH15985A/en
Priority to US06/131,787 priority patent/US4320200A/en
Priority to DK338880A priority patent/DK148180B/en
Priority to CA000373582A priority patent/CA1121814A/en
Priority to US06/313,974 priority patent/US4360462A/en
Priority to YU01785/82A priority patent/YU178582A/en
Priority to SE8302517A priority patent/SE446004B/en
Publication of JPS6034556B2 publication Critical patent/JPS6034556B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

PURPOSE: Antibiotic substance C-15003 of the formula I [R is -CO-CH(CH -CO-CH(CH2)2, -CO-CH2-CH2-CH3, -CO-CH2-CH(CH3)2]. The substances having R group given above are called as antibiotic substance C-15003p-3, C-15003p-3', and C-15003p-4, respectively.
COPYRIGHT: (C)1978,JPO&Japio
JP52037166A 1977-03-31 1977-03-31 Antibiotic C-15003 Expired JPS6034556B2 (en)

Priority Applications (45)

Application Number Priority Date Filing Date Title
JP52037166A JPS6034556B2 (en) 1977-03-31 1977-03-31 Antibiotic C-15003
US05/811,448 US4162940A (en) 1977-03-31 1977-06-29 Method for producing Antibiotic C-15003 by culturing nocardia
AU29074/77A AU510499B2 (en) 1977-03-31 1977-09-23 Antibiotic 0-15003
AU29072/77A AU506415B2 (en) 1977-03-31 1977-09-23 Antibiotic c-15003
PH20297A PH13381A (en) 1977-03-31 1977-10-04 Antibiotic c-15003
FR7730339A FR2385714A1 (en) 1977-03-31 1977-10-07 NEW ANTIBIOTIC NAMED C-15003, ITS PREPARATION PROCESS AND ITS APPLICATION AS A MEDICINAL PRODUCT
SU772529301A SU741804A3 (en) 1977-03-31 1977-10-07 Method of preparing antibiotic
GR54548A GR66051B (en) 1977-03-31 1977-10-11
YU02453/77A YU245377A (en) 1977-03-31 1977-10-12 Process for producing antibiotics
CS776678A CS214749B2 (en) 1977-03-31 1977-10-13 Means for treating the diseased plants and method of preparation of active substance
NLAANVRAGE7711274,A NL188102C (en) 1977-03-31 1977-10-13 METHOD FOR PREPARING ANTIBIOTICS.
SE7711542A SE442873B (en) 1977-03-31 1977-10-13 PROCEDURE FOR PREPARING A NEW ANTIBIOTICUM C-15003 WITH STATED FORM BY CULTIVATION OF NOCARDIA NO C-15003 (IFO 13726, FERM 3992, ATCC 31281)
NL7711272A NL7711272A (en) 1977-03-31 1977-10-13 PROCESS FOR PREPARING PHARMACEUTICAL PREPARATIONS, AND FORMED PHARMACEUTICAL PREPARATIONS.
HU802440A HU187372B (en) 1977-03-31 1977-10-13 Process for the preparation of c-15003 p-o antibiotic
HU77TA1459A HU178359B (en) 1977-03-31 1977-10-13 Process for preparing the antibiotic c-15003
DE19772746209 DE2746209A1 (en) 1977-03-31 1977-10-14 NEW ANTIBIOTIC AND METHOD FOR MANUFACTURING IT
IE2101/77A IE46064B1 (en) 1977-03-31 1977-10-14 Antibiotic c-15003
DE19772746252 DE2746252A1 (en) 1977-03-31 1977-10-14 ANTIBIOTIC C-15003 MEDICINAL PRODUCT FOR THE TREATMENT OF TUMOROUS WARM BLUETERS
ES463207A ES463207A1 (en) 1977-03-31 1977-10-14 Antibiotic c-15003
CA288,731A CA1107212A (en) 1977-03-31 1977-10-14 Antibiotic c-15003
DK458877A DK458877A (en) 1977-03-31 1977-10-14 ANTIBIOTICS
GB42823/77A GB1592264A (en) 1977-03-31 1977-10-14 Treatment of tumor-carrying animal with antibiotic c-15003
GB42822/77A GB1586688A (en) 1977-03-31 1977-10-14 Antibiotic c-15003
AT0736277A AT364081B (en) 1977-03-31 1977-10-14 METHOD FOR PRODUCING NEW ANTIBIOTICS
PL1977221358A PL124349B1 (en) 1977-03-31 1977-10-15 Process for preparing maytansinol
PL1977201541A PL122289B1 (en) 1977-03-31 1977-10-15 Process for preparing novel antibiotic
CH1260577A CH637137A5 (en) 1977-03-31 1978-01-01 Antibiotic and process for its preparation
IT21818/78A IT1094308B (en) 1977-03-31 1978-03-30 ANTIBIOTIC COMPOSITION AND RELATED PROCEDURE FOR TREATMENT OF ANIMALS AFFECTED BY TUMORS
IT21817/78A IT1094020B (en) 1977-03-31 1978-03-30 ANTIBIOTICC C-15003 AND PROCEDURE FOR THE PRODUCTION OF IT AND ITS DERIVATIVES
PT67854A PT67854B (en) 1977-03-31 1978-03-30 Antibiotic c-15003
ZA00781863A ZA781863B (en) 1977-03-31 1978-03-31 Treatment of tumor-carrying animal with antibiotic c-15003
BE186486A BE865589A (en) 1977-03-31 1978-03-31 ANTIBIOTICS AND THEIR PREPARATION
BE186487A BE865590A (en) 1977-03-31 1978-03-31 ANTIBIOTIC COMPOSITIONS AND THEIR USE
ZA00781862A ZA781862B (en) 1977-03-31 1978-03-31 Antibiotic c-15003
SU782627804A SU890978A3 (en) 1977-03-31 1978-06-20 Method of preparing c-15003p-0 antibiotic
ES472230A ES472230A1 (en) 1977-03-31 1978-07-31 Antibiotic c-15003
AT822678A AT362061B (en) 1977-03-31 1978-11-17 METHOD FOR PRODUCING A NEW ANTIBIOTIC
US05/972,492 US4225494A (en) 1977-03-31 1978-12-22 Maytansinol esters
PH22216A PH15985A (en) 1977-03-31 1979-02-20 A method for producing maytansinol
US06/131,787 US4320200A (en) 1977-03-31 1980-03-19 Antibiotic
DK338880A DK148180B (en) 1977-03-31 1980-08-06 METHOD OF MANUFACTURING MAYTANSINOL
CA000373582A CA1121814A (en) 1977-03-31 1981-03-20 Antibiotic c-15003
US06/313,974 US4360462A (en) 1977-03-31 1981-10-22 Process for preparing maytansinol
YU01785/82A YU178582A (en) 1977-03-31 1982-08-17 Process for obtaining antibiotics
SE8302517A SE446004B (en) 1977-03-31 1983-05-03 PROCEDURE FOR THE PREPARATION OF ANTIBIOTIC C-15003 P-O (MAYTANSINOL)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52037166A JPS6034556B2 (en) 1977-03-31 1977-03-31 Antibiotic C-15003

Publications (2)

Publication Number Publication Date
JPS53130693A true JPS53130693A (en) 1978-11-14
JPS6034556B2 JPS6034556B2 (en) 1985-08-09

Family

ID=12490004

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52037166A Expired JPS6034556B2 (en) 1977-03-31 1977-03-31 Antibiotic C-15003

Country Status (6)

Country Link
JP (1) JPS6034556B2 (en)
AT (1) AT364081B (en)
BE (2) BE865589A (en)
HU (1) HU187372B (en)
SU (2) SU741804A3 (en)
ZA (2) ZA781862B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008526267A (en) * 2005-01-19 2008-07-24 イミュノジェン・インコーポレーテッド Method for producing ansamitocin
CN116421733A (en) * 2023-06-08 2023-07-14 金宇保灵生物药品有限公司 Vaccine heat-resistant protective agent for live vaccine of swine pasteurellosis

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3486248T3 (en) * 2012-09-26 2021-07-12 Immunogen Inc IMPROVED PROCEDURES FOR ACYLATION OF MAYTANSINOL

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008526267A (en) * 2005-01-19 2008-07-24 イミュノジェン・インコーポレーテッド Method for producing ansamitocin
CN116421733A (en) * 2023-06-08 2023-07-14 金宇保灵生物药品有限公司 Vaccine heat-resistant protective agent for live vaccine of swine pasteurellosis
CN116421733B (en) * 2023-06-08 2023-09-12 金宇保灵生物药品有限公司 Vaccine heat-resistant protective agent for live vaccine of swine pasteurellosis

Also Published As

Publication number Publication date
AT364081B (en) 1981-09-25
BE865589A (en) 1978-10-02
SU741804A3 (en) 1980-06-15
ZA781862B (en) 1979-03-28
ZA781863B (en) 1979-03-28
JPS6034556B2 (en) 1985-08-09
SU890978A3 (en) 1981-12-15
HU187372B (en) 1985-12-28
ATA736277A (en) 1981-02-15
BE865590A (en) 1978-10-02

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