KR100247853B1 - D-알파-아미노산의 제조방법 - Google Patents

D-알파-아미노산의 제조방법 Download PDF

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Publication number
KR100247853B1
KR100247853B1 KR1019920701904A KR920701904A KR100247853B1 KR 100247853 B1 KR100247853 B1 KR 100247853B1 KR 1019920701904 A KR1019920701904 A KR 1019920701904A KR 920701904 A KR920701904 A KR 920701904A KR 100247853 B1 KR100247853 B1 KR 100247853B1
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South Korea
Prior art keywords
carbamoyl
amino acid
enzyme
amino acids
dna
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Expired - Fee Related
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KR1019920701904A
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English (en)
Korean (ko)
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KR920703834A (ko
Inventor
난바히로까즈
야마다유끼오
다까노마사유끼
이께나까야스히로
다까하시사또미
야지마가즈요시
Original Assignee
후루타 다케시
가네가후치 가가쿠고교 가부시키가이샤
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Publication of KR920703834A publication Critical patent/KR920703834A/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1019920701904A 1990-12-07 1992-08-07 D-알파-아미노산의 제조방법 Expired - Fee Related KR100247853B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP40084890 1990-12-07
JP90-400848 1990-12-07
JP90-407922 1990-12-27
JP40792290 1990-12-27
JP91-078840 1991-04-11
JP7884091 1991-04-11
JP91-78840 1991-04-11

Publications (2)

Publication Number Publication Date
KR920703834A KR920703834A (ko) 1992-12-18
KR100247853B1 true KR100247853B1 (ko) 2000-03-15

Family

ID=27302825

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019920701904A Expired - Fee Related KR100247853B1 (ko) 1990-12-07 1992-08-07 D-알파-아미노산의 제조방법
KR1019997006525A Expired - Fee Related KR100257212B1 (en) 1990-12-07 1999-07-19 Process for production of d-alpha-amino acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019997006525A Expired - Fee Related KR100257212B1 (en) 1990-12-07 1999-07-19 Process for production of d-alpha-amino acids

Country Status (7)

Country Link
US (2) US5565344A (https=)
EP (1) EP0515698B1 (https=)
KR (2) KR100247853B1 (https=)
CN (1) CN1057568C (https=)
DE (1) DE69129899T2 (https=)
ES (1) ES2121001T3 (https=)
WO (1) WO1992010579A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824522A (en) * 1990-12-07 1998-10-20 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Recombinant decarbamylases for producing D-α-amino acids
SG54305A1 (en) * 1991-06-12 1998-11-16 Kanegafuchi Chemical Ind Immobilized enzyme preparation and process for producing d--g(a)-amino acid
WO1994000577A1 (en) * 1992-06-30 1994-01-06 Smithkline Beecham P.L.C. D-n-carbamoyl-amino acid amidohydrolase and hydantoinase
DE69334157T2 (de) * 1992-08-10 2008-04-17 Kanegafuchi Kagaku Kogyo K.K. Expressionsvektor pUC NT und ihre Verwendung
KR100328111B1 (ko) * 1992-10-05 2002-03-09 후루타 다케시 데카르바밀라제의 제조방법
DE4316928C2 (de) * 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
DE4328829A1 (de) * 1993-08-27 1995-03-02 Boehringer Mannheim Gmbh Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
IT1269321B (it) * 1994-04-15 1997-03-26 Eniricerche Spa Mutanti stabili della d-n- -carbamilasi
IT1274167B (it) * 1994-04-15 1997-07-15 Eniricerche Spa Procedimento per la produzione di d- -amminoacidi
EP0725142B1 (en) * 1994-06-24 2003-09-10 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for producing d-amino acid by using composite immobilized enzyme preparation
JP2924679B2 (ja) * 1994-12-26 1999-07-26 田辺製薬株式会社 Ｄ−リジンの製法
CN100516197C (zh) * 1994-12-28 2009-07-22 钟渊化学工业株式会社 生产D-N-氨基甲酰基-α-氨基酸的方法
EP0735143B1 (en) * 1995-03-28 1998-11-18 Tanabe Seiyaku Co., Ltd. Process for preparing D-amino acids
IT1276163B1 (it) 1995-11-23 1997-10-27 Eniricerche Spa Procedimento migliorato per la preparazione di d-alfa-amminoacidi
US7101838B2 (en) 1997-08-05 2006-09-05 The Trustees Of Columbia University In The City Of New York Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
JP2001069981A (ja) * 1999-08-31 2001-03-21 Kanegafuchi Chem Ind Co Ltd デカルバミラーゼの立体構造およびその利用法
DE60127381D1 (de) * 2000-01-21 2007-05-03 Biomarin Pharm Inc Flavobakterium heparinum expressions-system
EP1179599A3 (en) 2000-07-13 2003-07-09 Ajinomoto Co., Inc. Method for producing lysine derivative
US6822116B2 (en) * 2002-05-24 2004-11-23 Biocatalytics, Inc. Method for producing D-allo -isoleucine
US6830904B2 (en) * 2002-08-30 2004-12-14 Biocatalytics, Inc. Methods for producing diastereomers of isoleucine
WO2005052145A2 (en) * 2003-10-07 2005-06-09 University Of Florida Recombinant alkaliizing bacteria
WO2007040272A1 (ja) * 2005-10-06 2007-04-12 Kaneka Corporation Ｄ－（４－アミノメチル）フェニルアラニン誘導体の製造法
CN104830824A (zh) * 2015-05-15 2015-08-12 南通荣泰生物科技有限公司 一种d型水解酶的生产工艺
CN106754558B (zh) * 2017-01-25 2020-12-08 中国人民解放军第二军医大学 一株产低温活性β-半乳糖苷酶的极地来源的细长赖氨酸芽孢杆菌及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312948A (en) * 1978-05-23 1982-01-26 Snamprogetti S.P.A. Enzymic microbiological process for producing optically active aminoacids starting from hydantoins and/or racemic carbamoyl derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1039757B (it) * 1975-07-10 1979-12-10 Snam Progetti Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione
JPS5588697A (en) * 1978-12-27 1980-07-04 Ajinomoto Co Inc Preparation of d-alpha-amino acid
JPS5718793A (en) * 1980-07-08 1982-01-30 Kao Corp Granulation of coal-water slurry
DE3486188T2 (de) * 1983-02-17 1993-12-02 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von L-Tyrosin.
JP2679031B2 (ja) * 1986-07-16 1997-11-19 味の素株式会社 アミノ酸の製造法及びアミノ酸生産菌
DE3786511T2 (de) * 1986-09-17 1994-01-13 Beecham Group Plc Immobilisiertes Enzympräparat und seine Verwendung.
JPH01320991A (ja) * 1988-06-20 1989-12-27 Kanegafuchi Chem Ind Co Ltd Ｄ−ホモフエニルアラニン類の製造方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312948A (en) * 1978-05-23 1982-01-26 Snamprogetti S.P.A. Enzymic microbiological process for producing optically active aminoacids starting from hydantoins and/or racemic carbamoyl derivatives

Also Published As

Publication number Publication date
EP0515698A1 (en) 1992-12-02
CN1063310A (zh) 1992-08-05
KR100257212B1 (en) 2000-05-15
DE69129899T2 (de) 1999-01-14
WO1992010579A1 (fr) 1992-06-25
EP0515698A4 (https=) 1994-02-09
ES2121001T3 (es) 1998-11-16
US5565344A (en) 1996-10-15
CN1057568C (zh) 2000-10-18
DE69129899D1 (de) 1998-09-03
US5695968A (en) 1997-12-09
KR920703834A (ko) 1992-12-18
EP0515698B1 (en) 1998-07-29

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