ES2121001T3 - Procedimiento de produccion de d-alfa aminoacidos. - Google Patents

Procedimiento de produccion de d-alfa aminoacidos.

Info

Publication number
ES2121001T3
ES2121001T3 ES92900888T ES92900888T ES2121001T3 ES 2121001 T3 ES2121001 T3 ES 2121001T3 ES 92900888 T ES92900888 T ES 92900888T ES 92900888 T ES92900888 T ES 92900888T ES 2121001 T3 ES2121001 T3 ES 2121001T3
Authority
ES
Spain
Prior art keywords
amino acid
amino acids
production procedure
alpha amino
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92900888T
Other languages
English (en)
Inventor
Hironori Nanba
Yukio Yamada
Masayuki Takano
Yasuhiro Ikenaka
Satomi Takahashi
Kazuyoshi Yajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Application granted granted Critical
Publication of ES2121001T3 publication Critical patent/ES2121001T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A UN GEN QUE PERTENECE A AMIDOHIDROLASA DE AMINOACIDO D-N-CARBAMOILO-O CIDO D-NCARBAMOILO-OANTE QUE COMPRENDE UN FRAGMENTO DE ADN QUE CONTIENE EL GEN INTEGRADO EN UN VECTOR; UN MICROORGANISMO QUE PERTENECE AL GENERO ESCHERICHIA, PSEUDOMONAS, FLAVOBACTERIUM, BACILLUS, SERRATIA, CORYNEBACTERIUM O BREVIBACTERIUM Y TRANSFORMADO MEDIANTE LA INTEGRACION DEL PLASMIDO RECOMBINANTE EN EL MISMO; UN PROCESO PARA LA PRODUCCION DE AMIDOHIDROLASA DE AMINOACIDO D-N-CARBA-MOILO-O DOHIDROLASA DE AMINOACIDO D-N-CARBAMOILO-OISMO; Y UN PROCESO PARA LA PRODUCCION DE AMINOACIDO D-O ACCION DE LA AMIDOHIDROLASA. LA AMIDOHIDROLASA PUEDE UTILIZARSE TAMBIEN EN UN ESTADO INMOVILIZADO EN UN PORTADOR.
ES92900888T 1990-12-07 1991-12-06 Procedimiento de produccion de d-alfa aminoacidos. Expired - Lifetime ES2121001T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP40084890 1990-12-07
JP40792290 1990-12-27
JP7884091 1991-04-11

Publications (1)

Publication Number Publication Date
ES2121001T3 true ES2121001T3 (es) 1998-11-16

Family

ID=27302825

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92900888T Expired - Lifetime ES2121001T3 (es) 1990-12-07 1991-12-06 Procedimiento de produccion de d-alfa aminoacidos.

Country Status (7)

Country Link
US (2) US5565344A (es)
EP (1) EP0515698B1 (es)
KR (2) KR100247853B1 (es)
CN (1) CN1057568C (es)
DE (1) DE69129899T2 (es)
ES (1) ES2121001T3 (es)
WO (1) WO1992010579A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824522A (en) * 1990-12-07 1998-10-20 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Recombinant decarbamylases for producing D-α-amino acids
WO1992022643A1 (en) * 1991-06-12 1992-12-23 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha IMMOBILIZED ENZYME PREPARATION AND PRODUCTION OF D-α-AMINO ACID
EP1568778A1 (en) * 1992-06-30 2005-08-31 Smithkline Beecham Plc Hydantoinase from agrobacterium
ES2231772T3 (es) * 1992-08-10 2005-05-16 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adn codante para la descarbamilasa con termoestabilidad mejorada y uso del mismo.
DE69330343T2 (de) * 1992-10-05 2002-05-02 Kanegafuchi Chemical Ind Verfahren zur herstellung von d-alpha-aminosäuren
DE4316928C2 (de) * 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
DE4328829A1 (de) * 1993-08-27 1995-03-02 Boehringer Mannheim Gmbh Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
IT1274167B (it) * 1994-04-15 1997-07-15 Eniricerche Spa Procedimento per la produzione di d- -amminoacidi
IT1269321B (it) * 1994-04-15 1997-03-26 Eniricerche Spa Mutanti stabili della d-n- -carbamilasi
WO1996000296A1 (fr) * 1994-06-24 1996-01-04 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Procede de production de d-amino acide au moyen d'une preparation a base d'une enzyme composite immobilisee
JP2924679B2 (ja) 1994-12-26 1999-07-26 田辺製薬株式会社 D−リジンの製法
ES2281075T3 (es) * 1994-12-28 2007-09-16 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Un procedimiento para producir d-n-carbamoil-alfa-aminoacidos.
EP0735143B1 (en) * 1995-03-28 1998-11-18 Tanabe Seiyaku Co., Ltd. Process for preparing D-amino acids
IT1276163B1 (it) 1995-11-23 1997-10-27 Eniricerche Spa Procedimento migliorato per la preparazione di d-alfa-amminoacidi
US7101838B2 (en) 1997-08-05 2006-09-05 The Trustees Of Columbia University In The City Of New York Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
JP2001069981A (ja) * 1999-08-31 2001-03-21 Kanegafuchi Chem Ind Co Ltd デカルバミラーゼの立体構造およびその利用法
AU5790801A (en) * 2000-01-21 2001-07-31 Biomarin Pharmaceutical Inc. Flavobacterium heparinum expression system
EP1179599A3 (en) 2000-07-13 2003-07-09 Ajinomoto Co., Inc. Method for producing lysine derivative
US6822116B2 (en) * 2002-05-24 2004-11-23 Biocatalytics, Inc. Method for producing D-allo -isoleucine
US6830904B2 (en) * 2002-08-30 2004-12-14 Biocatalytics, Inc. Methods for producing diastereomers of isoleucine
US20070212311A1 (en) * 2003-10-07 2007-09-13 University Of Florida Research Foundation, Inc. Recombinant Alkalinizing Bacteria
WO2007040272A1 (ja) * 2005-10-06 2007-04-12 Kaneka Corporation D-(4-アミノメチル)フェニルアラニン誘導体の製造法
CN104830824A (zh) * 2015-05-15 2015-08-12 南通荣泰生物科技有限公司 一种d型水解酶的生产工艺
CN106754558B (zh) * 2017-01-25 2020-12-08 中国人民解放军第二军医大学 一株产低温活性β-半乳糖苷酶的极地来源的细长赖氨酸芽孢杆菌及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1039757B (it) * 1975-07-10 1979-12-10 Snam Progetti Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione
IT1109506B (it) * 1978-05-23 1985-12-16 Snam Progetti Processo enzimatico-microbiologico per la produzione di amminoacidi otticamente attivi a partire da idantoine e/o carbamil-derivati racemi
JPS5588697A (en) * 1978-12-27 1980-07-04 Ajinomoto Co Inc Preparation of d-alpha-amino acid
JPS5718793A (en) * 1980-07-08 1982-01-30 Kao Corp Granulation of coal-water slurry
EP0334391B1 (en) * 1983-02-17 1993-05-12 Kyowa Hakko Kogyo Co., Ltd. Process for preparing l-isoleucine
JP2679031B2 (ja) * 1986-07-16 1997-11-19 味の素株式会社 アミノ酸の製造法及びアミノ酸生産菌
DE3786511T2 (de) * 1986-09-17 1994-01-13 Beecham Group Plc Immobilisiertes Enzympräparat und seine Verwendung.
JPH01320991A (ja) * 1988-06-20 1989-12-27 Kanegafuchi Chem Ind Co Ltd D−ホモフエニルアラニン類の製造方法

Also Published As

Publication number Publication date
EP0515698A4 (es) 1994-02-09
EP0515698B1 (en) 1998-07-29
CN1063310A (zh) 1992-08-05
WO1992010579A1 (en) 1992-06-25
KR920703834A (ko) 1992-12-18
DE69129899D1 (de) 1998-09-03
US5695968A (en) 1997-12-09
KR100257212B1 (en) 2000-05-15
US5565344A (en) 1996-10-15
CN1057568C (zh) 2000-10-18
DE69129899T2 (de) 1999-01-14
EP0515698A1 (en) 1992-12-02
KR100247853B1 (ko) 2000-03-15

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