KR100257212B1 - Process for production of d-alpha-amino acids - Google Patents

Process for production of d-alpha-amino acids Download PDF

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Publication number
KR100257212B1
KR100257212B1 KR1019997006525A KR19997006525A KR100257212B1 KR 100257212 B1 KR100257212 B1 KR 100257212B1 KR 1019997006525 A KR1019997006525 A KR 1019997006525A KR 19997006525 A KR19997006525 A KR 19997006525A KR 100257212 B1 KR100257212 B1 KR 100257212B1
Authority
KR
South Korea
Prior art keywords
alpha
production
amino acids
acids
amino
Prior art date
Application number
KR1019997006525A
Other languages
English (en)
Inventor
Hirokazu Nanba
Yukio Yamada
Masayuki Takano
Yasuhiro Ikenaka
Satomi Takahashi
Kazuyoshi Yajima
Original Assignee
Kanegafuchi Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Ind filed Critical Kanegafuchi Chemical Ind
Application granted granted Critical
Publication of KR100257212B1 publication Critical patent/KR100257212B1/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/009Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving hydantoins or carbamoylamino compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1019997006525A 1990-12-07 1999-07-19 Process for production of d-alpha-amino acids KR100257212B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP40084890 1990-12-07
JP40792290 1990-12-27
JP7884091 1991-04-11
PCT/JP1991/001696 WO1992010579A1 (en) 1990-12-07 1991-12-06 PROCESS FOR PRODUCING D-α-AMINO ACID

Publications (1)

Publication Number Publication Date
KR100257212B1 true KR100257212B1 (en) 2000-05-15

Family

ID=27302825

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019920701904A KR100247853B1 (ko) 1990-12-07 1992-08-07 D-알파-아미노산의 제조방법
KR1019997006525A KR100257212B1 (en) 1990-12-07 1999-07-19 Process for production of d-alpha-amino acids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019920701904A KR100247853B1 (ko) 1990-12-07 1992-08-07 D-알파-아미노산의 제조방법

Country Status (7)

Country Link
US (2) US5565344A (ko)
EP (1) EP0515698B1 (ko)
KR (2) KR100247853B1 (ko)
CN (1) CN1057568C (ko)
DE (1) DE69129899T2 (ko)
ES (1) ES2121001T3 (ko)
WO (1) WO1992010579A1 (ko)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824522A (en) * 1990-12-07 1998-10-20 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Recombinant decarbamylases for producing D-α-amino acids
SG54305A1 (en) * 1991-06-12 1998-11-16 Kanegafuchi Chemical Ind Immobilized enzyme preparation and process for producing d--g(a)-amino acid
JP3510625B2 (ja) * 1992-06-30 2004-03-29 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー D−n−カルバモイル−アミノ酸アミドヒドロラーゼおよびヒダントイナーゼ
KR100266920B1 (ko) * 1992-08-10 2003-12-31 가네가후치 가가쿠고교 가부시키가이샤 내열성이 향상된 데카르바밀라아제를 코딩하는 dna 및 그의 용도
SG55164A1 (en) * 1992-10-05 1998-12-21 Kanegafuchi Chemical Ind Process for the production of d--g(a)-amino acid
DE4316928C2 (de) * 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
DE4328829A1 (de) * 1993-08-27 1995-03-02 Boehringer Mannheim Gmbh Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
IT1274167B (it) * 1994-04-15 1997-07-15 Eniricerche Spa Procedimento per la produzione di d- -amminoacidi
IT1269321B (it) * 1994-04-15 1997-03-26 Eniricerche Spa Mutanti stabili della d-n- -carbamilasi
DE69531725T2 (de) * 1994-06-24 2004-07-08 Kanegafuchi Kagaku Kogyo K.K. Verfahren zur herstellung von d-aminosäure durch eine zusammengesetzte immobilisierte enzymenverbindung
JP2924679B2 (ja) * 1994-12-26 1999-07-26 田辺製薬株式会社 D−リジンの製法
KR100244066B1 (ko) * 1994-12-28 2000-02-01 후루따 다케시 D-N-카르바모일-α-아미노산의 제조법
DE69600978T2 (de) * 1995-03-28 1999-04-15 Tanabe Seiyaku Co Verfahren zur Herstellung von D-Aminosäuren
IT1276163B1 (it) 1995-11-23 1997-10-27 Eniricerche Spa Procedimento migliorato per la preparazione di d-alfa-amminoacidi
US7101838B2 (en) 1997-08-05 2006-09-05 The Trustees Of Columbia University In The City Of New York Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
JP2001069981A (ja) * 1999-08-31 2001-03-21 Kanegafuchi Chem Ind Co Ltd デカルバミラーゼの立体構造およびその利用法
JP2003520598A (ja) * 2000-01-21 2003-07-08 アイベックス ファーマシューティカルズ インコーポレイティッド フラボバクテリウム・ヘパリナム発現系
EP1179599A3 (en) 2000-07-13 2003-07-09 Ajinomoto Co., Inc. Method for producing lysine derivative
US6822116B2 (en) * 2002-05-24 2004-11-23 Biocatalytics, Inc. Method for producing D-allo -isoleucine
US6830904B2 (en) * 2002-08-30 2004-12-14 Biocatalytics, Inc. Methods for producing diastereomers of isoleucine
WO2005052145A2 (en) * 2003-10-07 2005-06-09 University Of Florida Recombinant alkaliizing bacteria
WO2007040272A1 (ja) * 2005-10-06 2007-04-12 Kaneka Corporation D-(4-アミノメチル)フェニルアラニン誘導体の製造法
CN104830824A (zh) * 2015-05-15 2015-08-12 南通荣泰生物科技有限公司 一种d型水解酶的生产工艺
CN106754558B (zh) * 2017-01-25 2020-12-08 中国人民解放军第二军医大学 一株产低温活性β-半乳糖苷酶的极地来源的细长赖氨酸芽孢杆菌及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1039757B (it) * 1975-07-10 1979-12-10 Snam Progetti Complessi enzimatici atti a trasformare idantoine raceme in am minoacidi otticamente attivi e loro applicazione
IT1109506B (it) * 1978-05-23 1985-12-16 Snam Progetti Processo enzimatico-microbiologico per la produzione di amminoacidi otticamente attivi a partire da idantoine e/o carbamil-derivati racemi
JPS5588697A (en) * 1978-12-27 1980-07-04 Ajinomoto Co Inc Preparation of d-alpha-amino acid
JPS5718793A (en) * 1980-07-08 1982-01-30 Kao Corp Granulation of coal-water slurry
WO1984003301A1 (en) * 1983-02-17 1984-08-30 Kyowa Hakko Kogyo Kk Process for preparing amino acid
JP2679031B2 (ja) * 1986-07-16 1997-11-19 味の素株式会社 アミノ酸の製造法及びアミノ酸生産菌
ES2058121T3 (es) * 1986-09-17 1994-11-01 Beecham Group Plc Preparacion enzimatica inmovilizada y su uso.
JPH01320991A (ja) * 1988-06-20 1989-12-27 Kanegafuchi Chem Ind Co Ltd D−ホモフエニルアラニン類の製造方法

Also Published As

Publication number Publication date
WO1992010579A1 (en) 1992-06-25
US5695968A (en) 1997-12-09
ES2121001T3 (es) 1998-11-16
US5565344A (en) 1996-10-15
KR100247853B1 (ko) 2000-03-15
DE69129899D1 (de) 1998-09-03
DE69129899T2 (de) 1999-01-14
EP0515698A4 (ko) 1994-02-09
EP0515698B1 (en) 1998-07-29
CN1057568C (zh) 2000-10-18
KR920703834A (ko) 1992-12-18
CN1063310A (zh) 1992-08-05
EP0515698A1 (en) 1992-12-02

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