KR100195345B1 - 신규 피리도[2,3-f][1,4]티아제핀 및 피리도[3,2-b][1,5]벤조티아제핀 - Google Patents

신규 피리도[2,3-f][1,4]티아제핀 및 피리도[3,2-b][1,5]벤조티아제핀 Download PDF

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KR100195345B1
KR100195345B1 KR1019910007086A KR910007086A KR100195345B1 KR 100195345 B1 KR100195345 B1 KR 100195345B1 KR 1019910007086 A KR1019910007086 A KR 1019910007086A KR 910007086 A KR910007086 A KR 910007086A KR 100195345 B1 KR100195345 B1 KR 100195345B1
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South Korea
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substituted
compound
straight
benzyl
alkyl
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Korean (ko)
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KR910020019A (ko
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제이.우스트로 데이비드
에이치.도드 존
에프.슈웬더 찰스
Original Assignee
벤자민 에프.람버트
오르토 파마슈티칼 코포레이션
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019910007086A 1990-05-03 1991-05-02 신규 피리도[2,3-f][1,4]티아제핀 및 피리도[3,2-b][1,5]벤조티아제핀 Expired - Fee Related KR100195345B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/518,351 US5075440A (en) 1990-05-03 1990-05-03 Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzothiazepines
US518,351 1990-05-03

Publications (2)

Publication Number Publication Date
KR910020019A KR910020019A (ko) 1991-12-19
KR100195345B1 true KR100195345B1 (ko) 1999-06-15

Family

ID=24063558

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910007086A Expired - Fee Related KR100195345B1 (ko) 1990-05-03 1991-05-02 신규 피리도[2,3-f][1,4]티아제핀 및 피리도[3,2-b][1,5]벤조티아제핀

Country Status (25)

Country Link
US (1) US5075440A (https=)
EP (1) EP0462696B1 (https=)
JP (1) JP3296499B2 (https=)
KR (1) KR100195345B1 (https=)
CN (2) CN1034077C (https=)
AT (1) ATE126231T1 (https=)
AU (1) AU651580B2 (https=)
CA (1) CA2041594C (https=)
DE (1) DE69111915T2 (https=)
DK (1) DK0462696T3 (https=)
ES (1) ES2079570T3 (https=)
FI (1) FI95912C (https=)
GR (1) GR3017305T3 (https=)
HK (1) HK51496A (https=)
HU (1) HU218909B (https=)
IE (1) IE68524B1 (https=)
IL (6) IL127047A0 (https=)
MY (1) MY106552A (https=)
NO (1) NO179411C (https=)
NZ (1) NZ237988A (https=)
PT (1) PT97547B (https=)
TN (1) TNSN91030A1 (https=)
TW (1) TW218878B (https=)
ZA (1) ZA913319B (https=)
ZW (1) ZW5291A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101233139B1 (ko) 2011-04-21 2013-02-21 주식회사 한서켐 라세믹 1,4-티아제핀 화합물의 분할 방법

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593335B1 (en) 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
US6265417B1 (en) 1997-12-18 2001-07-24 Abbott Laboratories Potassium channel openers
AU756505B2 (en) * 1997-12-18 2003-01-16 Abbott Laboratories Potassium channel openers
JPH11193289A (ja) * 1997-12-26 1999-07-21 Suntory Ltd ピロールスルホンアミド誘導体
US6482854B1 (en) * 1999-03-25 2002-11-19 Massachusetts Eye And Ear Infirmary Glaucoma treatment
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
HUP0201566A3 (en) * 1999-06-14 2004-03-01 Ortho Mcneil Pharm Inc Dithiepino[6,5-b]pyridines, their preparation pharmaceutical compositions containing thereof and an apparatus for their administering
ES2246248T3 (es) * 1999-07-12 2006-02-16 Ortho-Mcneil Pharmaceutical, Inc. Oxatiepino (6,5-b)dihidropiridinas, y composiciones y metodos relacionados.
US6472530B1 (en) 1999-09-22 2002-10-29 Ortho-Mcneil Pharmaceutical, Inc. Benzo-fused dithiepino[6,5-b]pyridines, and related compositions and methods
CA2396962A1 (en) 2000-01-12 2001-07-19 Ortho-Mcneil Pharmaceutical, Inc. Benzosulfones and related compositions and methods
AU783503B2 (en) * 2000-01-27 2005-11-03 Ortho-Mcneil Pharmaceutical, Inc. Benzoxathiepino(3,4-b)pyridine derivatives, process for their preparation and their use as medicaments
JP2003528104A (ja) 2000-03-23 2003-09-24 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド チエピノ［３，２−ｂ］ジヒドロピリジンおよび関連組成物ならびに方法
CN1444587A (zh) 2000-05-30 2003-09-24 奥索-麦克尼尔药品公司 二氢吡啶软药及相关组合物和方法
US20160207893A1 (en) * 2014-12-30 2016-07-21 Myotherix, Inc. Novel calcium modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1587128A (en) * 1977-04-07 1981-04-01 Hexachimie Benzothiazepine derivatives
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
FR2511683A1 (fr) * 1981-08-20 1983-02-25 Hexachimie Nouveaux derives de la pyrido (2,3-b) benzothiazepine(1,5) substituee en 5 par une carboxypiperazine, leur procede de preparation, leur application en therapeutique
EP0225175A3 (en) * 1985-11-28 1988-12-28 FISONS plc Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101233139B1 (ko) 2011-04-21 2013-02-21 주식회사 한서켐 라세믹 1,4-티아제핀 화합물의 분할 방법

Also Published As

Publication number Publication date
CA2041594A1 (en) 1991-11-04
IE68524B1 (en) 1996-06-26
IL120446A0 (en) 1997-07-13
HU911476D0 (en) 1991-11-28
KR910020019A (ko) 1991-12-19
TNSN91030A1 (fr) 1992-10-25
JPH04225986A (ja) 1992-08-14
ATE126231T1 (de) 1995-08-15
IE911488A1 (en) 1991-11-06
HU218909B (hu) 2000-12-28
IL120446A (en) 2000-08-31
IL127047A0 (en) 1999-09-22
HK51496A (en) 1996-03-29
IL127047A (en) 2000-10-31
PT97547A (pt) 1992-01-31
AU651580B2 (en) 1994-07-28
CN1056880A (zh) 1991-12-11
MY106552A (en) 1995-06-30
FI912124A7 (fi) 1991-11-04
IL97999A0 (en) 1992-06-21
FI912124A0 (fi) 1991-05-02
CN1034077C (zh) 1997-02-19
EP0462696B1 (en) 1995-08-09
ZW5291A1 (en) 1993-01-06
NO179411B (no) 1996-06-24
CN1039416C (zh) 1998-08-05
CA2041594C (en) 2002-07-23
AU7635491A (en) 1991-11-07
GR3017305T3 (en) 1995-12-31
ES2079570T3 (es) 1996-01-16
HUT60745A (en) 1992-10-28
IL120447A (en) 1999-12-22
IL97999A (en) 1997-06-10
TW218878B (https=) 1994-01-11
NO179411C (no) 1996-10-02
EP0462696A1 (en) 1991-12-27
DE69111915T2 (de) 1996-01-04
CN1118783A (zh) 1996-03-20
FI95912C (fi) 1996-04-10
NO911723L (no) 1991-11-04
DK0462696T3 (da) 1995-09-18
JP3296499B2 (ja) 2002-07-02
PT97547B (pt) 1998-08-31
US5075440A (en) 1991-12-24
NZ237988A (en) 1992-09-25
ZA913319B (en) 1993-01-27
NO911723D0 (no) 1991-05-02
FI95912B (fi) 1995-12-29
DE69111915D1 (de) 1995-09-14
IL120447A0 (en) 1997-07-13

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