KR100191191B1 - 인터루킨-8합성억제의 카르보스티릴 유도체 - Google Patents

인터루킨-8합성억제의 카르보스티릴 유도체 Download PDF

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Publication number
KR100191191B1
KR100191191B1 KR1019950702533A KR19950702533A KR100191191B1 KR 100191191 B1 KR100191191 B1 KR 100191191B1 KR 1019950702533 A KR1019950702533 A KR 1019950702533A KR 19950702533 A KR19950702533 A KR 19950702533A KR 100191191 B1 KR100191191 B1 KR 100191191B1
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KR
South Korea
Prior art keywords
salt
derivative represented
chlorobenzoylamino
quinolone
carbostyryl derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019950702533A
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English (en)
Korean (ko)
Other versions
KR950703957A (ko
Inventor
다까히데 마쓰다
시게루 오와다
히로시 무따
미끼 아이하라
히사오 다끼자와
겐이찌 이마가와
미끼오 기꾸찌
Original Assignee
오쓰까 아끼히꼬
오쓰까 세이야꾸 가부시키가이샤
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Publication date
Application filed by 오쓰까 아끼히꼬, 오쓰까 세이야꾸 가부시키가이샤 filed Critical 오쓰까 아끼히꼬
Publication of KR950703957A publication Critical patent/KR950703957A/ko
Application granted granted Critical
Publication of KR100191191B1 publication Critical patent/KR100191191B1/ko
Anticipated expiration legal-status Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
KR1019950702533A 1993-10-21 1994-10-17 인터루킨-8합성억제의 카르보스티릴 유도체 Expired - Fee Related KR100191191B1 (ko)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP26341793 1993-10-21
JP26341993 1993-10-21
JP93-263419 1993-10-21
JP93-263417 1993-10-21
JP93-263418 1993-10-21
JP26341893 1993-10-21
JP94-89641 1994-04-27
JP93-89641 1994-04-27
JP8964194 1994-04-27
PCT/JP1994/001739 WO1995011026A1 (en) 1993-10-21 1994-10-17 Carbostyril derivative for inhibiting production of interleukin-8

Publications (2)

Publication Number Publication Date
KR950703957A KR950703957A (ko) 1995-11-17
KR100191191B1 true KR100191191B1 (ko) 1999-06-15

Family

ID=27467652

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950702533A Expired - Fee Related KR100191191B1 (ko) 1993-10-21 1994-10-17 인터루킨-8합성억제의 카르보스티릴 유도체

Country Status (14)

Country Link
US (1) US5637597A (enExample)
EP (1) EP0674515B1 (enExample)
JP (1) JP2839847B2 (enExample)
KR (1) KR100191191B1 (enExample)
CN (1) CN1073418C (enExample)
AT (1) ATE184793T1 (enExample)
AU (1) AU683697B2 (enExample)
CA (1) CA2150546C (enExample)
DE (1) DE69420832T2 (enExample)
DK (1) DK0674515T3 (enExample)
ES (1) ES2138092T3 (enExample)
GR (1) GR3032091T3 (enExample)
TW (1) TW296983B (enExample)
WO (1) WO1995011026A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR004214A1 (es) * 1995-10-12 1998-11-04 Otsuka Pharma Co Ltd Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas
DE10029404B4 (de) * 2000-06-15 2009-10-29 Jagotec Ag Arzneiformulierung enthaltend Ciclosporin und deren Verwendung
FR2812548B1 (fr) * 2000-08-01 2002-09-20 Sanofi Synthelabo Utilisation de derives de quinolein-2(1h)-one ou un de leurs sels pharmaceutiquement acceptable pour la preparation d'un medicament destine au traitement de l'insuffisance renale
AU2003304040A1 (en) * 2002-10-08 2004-11-04 Viropharma Incorporated Anthranilic acid derivatives useful in treating infection with hepatitis c virus
KR100681360B1 (ko) 2003-07-30 2007-02-12 오츠카 세이야쿠 가부시키가이샤 타액분비 촉진용 카르보스티릴 유도체
TWI340650B (en) * 2004-01-21 2011-04-21 Otsuka Pharma Co Ltd Amine saly of carbostyril derivative
MY149159A (en) 2005-11-15 2013-07-31 Hoffmann La Roche Method for treating joint damage
WO2009022674A1 (en) * 2007-08-10 2009-02-19 Otsuka Pharmaceutical Co., Ltd. Medical composition containing rebamipide
KR101104634B1 (ko) * 2009-08-25 2012-01-12 한림제약(주) 레바미피드를 포함하는 류마티스 관절염 예방 또는 치료용 약학 조성물
KR101182114B1 (ko) * 2010-03-05 2012-09-12 한림제약(주) 유효성분으로서 레바미피드를 함유하는 골관절염 예방 또는 치료용 약학 조성물
WO2012114317A1 (en) 2011-02-25 2012-08-30 Nuformix Limited Novel rebamipide complexes and cocrystals
WO2012128394A1 (en) 2011-03-24 2012-09-27 Otsuka Pharmaceutical Co., Ltd. A pharmaceutical composition for treating a disease in the oral cavity comprising rebamipide
JP6294773B2 (ja) * 2014-06-27 2018-03-14 株式会社ナールスコーポレーション 口腔粘膜疾患の予防または治療用経口製剤
WO2022128054A1 (en) 2020-12-14 2022-06-23 Symrise Ag Medicament for fighting inflammatory conditions of human skin (iv)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578381A (en) * 1982-07-05 1986-03-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
GB8334494D0 (en) * 1983-12-24 1984-02-01 Tanabe Seiyaku Co Carbostyril derivatives
JPS63119467A (ja) * 1987-10-21 1988-05-24 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
JPH02178227A (ja) * 1988-12-28 1990-07-11 Otsuka Pharmaceut Co Ltd 腎炎治療剤
JP2812998B2 (ja) * 1989-08-14 1998-10-22 大塚製薬 株式会社 胃炎治療剤
WO1992021342A1 (en) * 1991-06-07 1992-12-10 Otsuka Pharmaceutical Co., Ltd. Antidiabetic
DE69230131T2 (de) * 1991-07-03 2000-03-02 Otsuka Pharmaceutical Co., Ltd. Apoptoseregulator
TW227558B (enExample) * 1992-05-14 1994-08-01 Otsuka Pharma Co Ltd
JP2872546B2 (ja) * 1992-11-26 1999-03-17 大塚製薬株式会社 腸粘膜障害保護剤
AU5715994A (en) * 1992-12-24 1994-07-19 Otsuka Pharmaceutical Co., Ltd. Psoriasis remedy
US5521185A (en) * 1993-03-02 1996-05-28 Otsuka Pharmaceutical Co., Ltd. Methods for inhibiting graft rejection and IL-1 production

Also Published As

Publication number Publication date
ATE184793T1 (de) 1999-10-15
JP2839847B2 (ja) 1998-12-16
ES2138092T3 (es) 2000-01-01
AU7864194A (en) 1995-05-08
EP0674515B1 (en) 1999-09-22
DE69420832T2 (de) 2000-01-13
JPH0812578A (ja) 1996-01-16
CA2150546C (en) 2004-11-09
KR950703957A (ko) 1995-11-17
CN1073418C (zh) 2001-10-24
US5637597A (en) 1997-06-10
DE69420832D1 (de) 1999-10-28
GR3032091T3 (en) 2000-03-31
CA2150546A1 (en) 1995-04-27
CN1117268A (zh) 1996-02-21
DK0674515T3 (da) 1999-12-20
EP0674515A1 (en) 1995-10-04
WO1995011026A1 (en) 1995-04-27
TW296983B (enExample) 1997-02-01
AU683697B2 (en) 1997-11-20

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