KE3028A - Vinca alkaloid derivatives - Google Patents

Vinca alkaloid derivatives

Info

Publication number
KE3028A
KE3028A KE3028A KE302880A KE3028A KE 3028 A KE3028 A KE 3028A KE 3028 A KE3028 A KE 3028A KE 302880 A KE302880 A KE 302880A KE 3028 A KE3028 A KE 3028A
Authority
KE
Kenya
Prior art keywords
vinca alkaloid
alkaloid derivatives
derivatives
vinca
alkaloid
Prior art date
Application number
KE3028A
Other languages
English (en)
Inventor
K Gerzon
G J Cullinan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of KE3028A publication Critical patent/KE3028A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
KE3028A 1973-04-02 1980-02-27 Vinca alkaloid derivatives KE3028A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (1)

Publication Number Publication Date
KE3028A true KE3028A (en) 1980-03-28

Family

ID=23363051

Family Applications (1)

Application Number Title Priority Date Filing Date
KE3028A KE3028A (en) 1973-04-02 1980-02-27 Vinca alkaloid derivatives

Country Status (28)

Country Link
JP (2) JPS5919117B2 (enExample)
AR (2) AR204004A1 (enExample)
AT (1) AT340605B (enExample)
BE (1) BE813168A (enExample)
BG (3) BG22831A3 (enExample)
CA (1) CA1042428A (enExample)
CH (1) CH603669A5 (enExample)
CS (1) CS185223B2 (enExample)
CY (1) CY1044A (enExample)
DD (1) DD113538A5 (enExample)
DE (1) DE2415980A1 (enExample)
DK (1) DK141511B (enExample)
ES (2) ES424882A1 (enExample)
FR (1) FR2223044B1 (enExample)
GB (1) GB1463575A (enExample)
HK (1) HK20180A (enExample)
HU (1) HU171572B (enExample)
IE (1) IE39071B1 (enExample)
IL (1) IL44415A (enExample)
KE (1) KE3028A (enExample)
MY (1) MY8100025A (enExample)
NL (1) NL181079C (enExample)
PH (1) PH13623A (enExample)
RO (2) RO77533A (enExample)
SE (1) SE416206B (enExample)
SU (4) SU731900A3 (enExample)
YU (3) YU39719B (enExample)
ZA (1) ZA741674B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (enExample) * 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4210584A (en) 1979-01-15 1980-07-01 Eli Lilly And Company Vindesine synthesis
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
LU83822A1 (fr) 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
EP1845974A1 (en) 2005-01-21 2007-10-24 Astex Therapeutics Limited Pharmaceutical compounds
EP1906948A4 (en) 2005-07-18 2010-03-17 Bipar Sciences Inc TREATMENT OF CANCER
WO2008030883A2 (en) 2006-09-05 2008-03-13 Bipar Sciences, Inc. Treatment of cancer
AU2007292306A1 (en) 2006-09-05 2008-03-13 Bipar Sciences, Inc. Inhibition of fatty acid synthesis by PARP inhibitors and methods of treatment thereof
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
WO2009064738A2 (en) 2007-11-12 2009-05-22 Bipar Sciences, Inc. Treatment of breast cancer with a parp inhibitor alone or in combination with anti-tumor agents
AU2014253584B2 (en) * 2013-04-19 2017-02-02 Jinan University Vinca Alkaloid Derivatives, Preparation Method therefor and Application thereof
CN113456797B (zh) * 2021-06-18 2024-03-08 暨南大学 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
DE2415980A1 (de) 1974-10-10
SU652896A3 (ru) 1979-03-15
NL181079C (nl) 1987-06-16
AR204004A1 (es) 1975-11-12
RO73524A (ro) 1984-10-31
YU81774A (en) 1982-05-31
IL44415A (en) 1978-08-31
AU6671974A (en) 1975-09-18
SE416206B (sv) 1980-12-08
DK141511C (enExample) 1980-09-29
CS185223B2 (en) 1978-09-15
BE813168A (fr) 1974-10-02
GB1463575A (en) 1977-02-02
RO77533A (ro) 1982-02-01
AR203882A1 (es) 1975-10-31
HU171572B (hu) 1978-02-28
ES424882A1 (es) 1976-12-16
JPS6033837B2 (ja) 1985-08-05
ES446571A1 (es) 1977-06-16
JPS5919117B2 (ja) 1984-05-02
BG21235A3 (bg) 1976-03-20
YU39875B (en) 1985-04-30
ATA267974A (de) 1977-04-15
IE39071B1 (en) 1978-08-02
SU784783A3 (ru) 1980-11-30
SU623522A3 (ru) 1978-09-05
AT340605B (de) 1977-12-27
FR2223044B1 (enExample) 1978-06-30
CA1042428A (en) 1978-11-14
DK141511B (da) 1980-04-08
YU113980A (en) 1982-05-31
IL44415A0 (en) 1974-06-30
ZA741674B (en) 1975-10-29
BG21612A3 (bg) 1976-07-20
IE39071L (en) 1974-10-02
CH603669A5 (enExample) 1978-08-31
JPS49128000A (enExample) 1974-12-07
DD113538A5 (enExample) 1975-06-12
MY8100025A (en) 1981-12-31
YU39876B (en) 1985-04-30
NL7404423A (enExample) 1974-10-04
FR2223044A1 (enExample) 1974-10-25
YU39719B (en) 1985-04-30
SU731900A3 (ru) 1980-04-30
NL181079B (nl) 1987-01-16
HK20180A (en) 1980-04-25
DE2415980C2 (enExample) 1989-11-09
RO73524B (ro) 1984-11-30
PH13623A (en) 1980-08-07
BG22831A3 (bg) 1977-04-20
CY1044A (en) 1980-08-01
JPS59193895A (ja) 1984-11-02
YU113880A (en) 1982-05-31

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