KE3028A - Vinca alkaloid derivatives - Google Patents

Vinca alkaloid derivatives

Info

Publication number
KE3028A
KE3028A KE3028A KE302880A KE3028A KE 3028 A KE3028 A KE 3028A KE 3028 A KE3028 A KE 3028A KE 302880 A KE302880 A KE 302880A KE 3028 A KE3028 A KE 3028A
Authority
KE
Kenya
Prior art keywords
vinca alkaloid
alkaloid derivatives
derivatives
vinca
alkaloid
Prior art date
Application number
KE3028A
Inventor
K Gerzon
G J Cullinan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of KE3028A publication Critical patent/KE3028A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KE3028A 1973-04-02 1980-02-27 Vinca alkaloid derivatives KE3028A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (1)

Publication Number Publication Date
KE3028A true KE3028A (en) 1980-03-28

Family

ID=23363051

Family Applications (1)

Application Number Title Priority Date Filing Date
KE3028A KE3028A (en) 1973-04-02 1980-02-27 Vinca alkaloid derivatives

Country Status (28)

Country Link
JP (2) JPS5919117B2 (en)
AR (2) AR204004A1 (en)
AT (1) AT340605B (en)
BE (1) BE813168A (en)
BG (3) BG21235A3 (en)
CA (1) CA1042428A (en)
CH (1) CH603669A5 (en)
CS (1) CS185223B2 (en)
CY (1) CY1044A (en)
DD (1) DD113538A5 (en)
DE (1) DE2415980A1 (en)
DK (1) DK141511B (en)
ES (2) ES424882A1 (en)
FR (1) FR2223044B1 (en)
GB (1) GB1463575A (en)
HK (1) HK20180A (en)
HU (1) HU171572B (en)
IE (1) IE39071B1 (en)
IL (1) IL44415A (en)
KE (1) KE3028A (en)
MY (1) MY8100025A (en)
NL (1) NL181079C (en)
PH (1) PH13623A (en)
RO (2) RO77533A (en)
SE (1) SE416206B (en)
SU (4) SU731900A3 (en)
YU (3) YU39719B (en)
ZA (1) ZA741674B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (en) * 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (en) * 1980-06-10 1981-09-30 Omnium Chimique Sa Process for the preparation of N- (vinblastinoyl-23) derivatives of amino acids and peptides.
LU83822A1 (en) 1981-12-08 1983-09-01 Omnichem Sa N- (VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2623504B1 (en) * 1987-11-25 1990-03-09 Adir NOVEL N- (VINBLASTINOYL-23) DERIVATIVES OF 1-AMINO METHYLPHOSPHONIC ACID, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HUT76925A (en) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bis-indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
CN101146532B (en) 2005-01-21 2012-05-09 阿斯泰克斯治疗有限公司 Pharmaceutical compounds
ZA200800907B (en) 2005-07-18 2010-04-28 Bipar Sciences Inc Treatment of cancer
US7994222B2 (en) 2006-09-05 2011-08-09 Bipar Sciences, Inc. Monitoring of the inhibition of fatty acid synthesis by iodo-nitrobenzamide compounds
JP2010502730A (en) 2006-09-05 2010-01-28 バイパー サイエンシズ，インコーポレイティド Cancer treatment
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
JP2011503111A (en) 2007-11-12 2011-01-27 バイパー サイエンシズ，インコーポレイティド Treatment of breast cancer with PARP inhibitors alone or in combination with antitumor agents
CN105121447B (en) * 2013-04-19 2018-02-02 暨南大学 Vinca derivative and its preparation method and application
CN113456797B (en) * 2021-06-18 2024-03-08 暨南大学 Application of vinblastine derivatives in preparation of medicines for treating osteosarcoma and/or soft tissue sarcoma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
YU39719B (en) 1985-04-30
IE39071B1 (en) 1978-08-02
YU39876B (en) 1985-04-30
NL181079C (en) 1987-06-16
AR204004A1 (en) 1975-11-12
SU623522A3 (en) 1978-09-05
CS185223B2 (en) 1978-09-15
BG21612A3 (en) 1976-07-20
YU39875B (en) 1985-04-30
SU784783A3 (en) 1980-11-30
FR2223044B1 (en) 1978-06-30
RO73524B (en) 1984-11-30
DE2415980A1 (en) 1974-10-10
JPS6033837B2 (en) 1985-08-05
SU731900A3 (en) 1980-04-30
JPS5919117B2 (en) 1984-05-02
YU113880A (en) 1982-05-31
PH13623A (en) 1980-08-07
DE2415980C2 (en) 1989-11-09
HK20180A (en) 1980-04-25
BG21235A3 (en) 1976-03-20
NL7404423A (en) 1974-10-04
RO77533A (en) 1982-02-01
ATA267974A (en) 1977-04-15
YU81774A (en) 1982-05-31
IL44415A0 (en) 1974-06-30
FR2223044A1 (en) 1974-10-25
IL44415A (en) 1978-08-31
MY8100025A (en) 1981-12-31
DK141511C (en) 1980-09-29
CY1044A (en) 1980-08-01
ES424882A1 (en) 1976-12-16
RO73524A (en) 1984-10-31
NL181079B (en) 1987-01-16
AR203882A1 (en) 1975-10-31
DD113538A5 (en) 1975-06-12
BG22831A3 (en) 1977-04-20
SU652896A3 (en) 1979-03-15
GB1463575A (en) 1977-02-02
IE39071L (en) 1974-10-02
JPS49128000A (en) 1974-12-07
DK141511B (en) 1980-04-08
HU171572B (en) 1978-02-28
ES446571A1 (en) 1977-06-16
YU113980A (en) 1982-05-31
CA1042428A (en) 1978-11-14
JPS59193895A (en) 1984-11-02
AT340605B (en) 1977-12-27
CH603669A5 (en) 1978-08-31
AU6671974A (en) 1975-09-18
SE416206B (en) 1980-12-08
BE813168A (en) 1974-10-02
ZA741674B (en) 1975-10-29

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