CH603669A5 - - Google Patents

Info

Publication number
CH603669A5
CH603669A5 CH446374A CH446374A CH603669A5 CH 603669 A5 CH603669 A5 CH 603669A5 CH 446374 A CH446374 A CH 446374A CH 446374 A CH446374 A CH 446374A CH 603669 A5 CH603669 A5 CH 603669A5
Authority
CH
Switzerland
Application number
CH446374A
Inventor
George Joseph Cullinan
Koert Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CH603669A5 publication Critical patent/CH603669A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CH446374A 1973-04-02 1974-03-29 CH603669A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (1)

Publication Number Publication Date
CH603669A5 true CH603669A5 (en) 1978-08-31

Family

ID=23363051

Family Applications (1)

Application Number Title Priority Date Filing Date
CH446374A CH603669A5 (en) 1973-04-02 1974-03-29

Country Status (28)

Country Link
JP (2) JPS5919117B2 (en)
AR (2) AR204004A1 (en)
AT (1) AT340605B (en)
BE (1) BE813168A (en)
BG (3) BG21612A3 (en)
CA (1) CA1042428A (en)
CH (1) CH603669A5 (en)
CS (1) CS185223B2 (en)
CY (1) CY1044A (en)
DD (1) DD113538A5 (en)
DE (1) DE2415980A1 (en)
DK (1) DK141511B (en)
ES (2) ES424882A1 (en)
FR (1) FR2223044B1 (en)
GB (1) GB1463575A (en)
HK (1) HK20180A (en)
HU (1) HU171572B (en)
IE (1) IE39071B1 (en)
IL (1) IL44415A (en)
KE (1) KE3028A (en)
MY (1) MY8100025A (en)
NL (1) NL181079C (en)
PH (1) PH13623A (en)
RO (2) RO77533A (en)
SE (1) SE416206B (en)
SU (4) SU731900A3 (en)
YU (3) YU39719B (en)
ZA (1) ZA741674B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (en) * 1976-09-08 1982-07-07 Lilly Co Eli
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (en) * 1980-06-10 1981-09-30 Omnium Chimique Sa Process for the preparation of N- (vinblastinoyl-23) derivatives of amino acids and peptides.
LU83822A1 (en) 1981-12-08 1983-09-01 Omnichem Sa N- (VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2623504B1 (en) * 1987-11-25 1990-03-09 Adir NOVEL N- (VINBLASTINOYL-23) DERIVATIVES OF 1-AMINO METHYLPHOSPHONIC ACID, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
HUT76925A (en) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bis-indole derivatives, process for the preparation thereof and pharmaceutical compositions containing them
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
CA2594474C (en) 2005-01-21 2016-03-29 Astex Therapeutics Limited Pharmaceutical compounds
CN101242822B (en) 2005-07-18 2011-08-24 彼帕科学公司 Medicine of ovarian cancer
JP2010502730A (en) 2006-09-05 2010-01-28 バイパー サイエンシズ,インコーポレイティド Cancer treatment
CN101534836B (en) 2006-09-05 2011-09-28 彼帕科学公司 Use of PARP inhibition in preparing medicine for obesity
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
WO2009064738A2 (en) 2007-11-12 2009-05-22 Bipar Sciences, Inc. Treatment of breast cancer with a parp inhibitor alone or in combination with anti-tumor agents
EP2987794B1 (en) * 2013-04-19 2018-05-30 Jinan University Vinblastine derivatives, preparation method therefor and application thereof
CN113456797B (en) * 2021-06-18 2024-03-08 暨南大学 Application of vinblastine derivatives in preparation of medicines for treating osteosarcoma and/or soft tissue sarcoma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
SU784783A3 (en) 1980-11-30
CY1044A (en) 1980-08-01
JPS59193895A (en) 1984-11-02
FR2223044A1 (en) 1974-10-25
YU39719B (en) 1985-04-30
RO77533A (en) 1982-02-01
SU731900A3 (en) 1980-04-30
AR203882A1 (en) 1975-10-31
DE2415980A1 (en) 1974-10-10
NL7404423A (en) 1974-10-04
JPS49128000A (en) 1974-12-07
BG21235A3 (en) 1976-03-20
SU652896A3 (en) 1979-03-15
ATA267974A (en) 1977-04-15
DK141511B (en) 1980-04-08
AT340605B (en) 1977-12-27
YU39875B (en) 1985-04-30
NL181079C (en) 1987-06-16
BE813168A (en) 1974-10-02
RO73524A (en) 1984-10-31
IE39071B1 (en) 1978-08-02
PH13623A (en) 1980-08-07
FR2223044B1 (en) 1978-06-30
YU113880A (en) 1982-05-31
KE3028A (en) 1980-03-28
ES446571A1 (en) 1977-06-16
ES424882A1 (en) 1976-12-16
HK20180A (en) 1980-04-25
AU6671974A (en) 1975-09-18
YU81774A (en) 1982-05-31
AR204004A1 (en) 1975-11-12
CA1042428A (en) 1978-11-14
GB1463575A (en) 1977-02-02
CS185223B2 (en) 1978-09-15
NL181079B (en) 1987-01-16
ZA741674B (en) 1975-10-29
DE2415980C2 (en) 1989-11-09
IL44415A0 (en) 1974-06-30
MY8100025A (en) 1981-12-31
IE39071L (en) 1974-10-02
DK141511C (en) 1980-09-29
YU113980A (en) 1982-05-31
RO73524B (en) 1984-11-30
HU171572B (en) 1978-02-28
SU623522A3 (en) 1978-09-05
SE416206B (en) 1980-12-08
BG21612A3 (en) 1976-07-20
JPS6033837B2 (en) 1985-08-05
YU39876B (en) 1985-04-30
DD113538A5 (en) 1975-06-12
BG22831A3 (en) 1977-04-20
IL44415A (en) 1978-08-31
JPS5919117B2 (en) 1984-05-02

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Legal Events

Date Code Title Description
PL Patent ceased
SPCF Supplementary protection certificate filed

Free format text: IKS 42863, 951024

SPCG Supplementary protection certificate granted

Free format text: IKS 42863/820316, 951024, EXPIRES:19970316