IL44415A - Vinblastine and leurocristine carboxamide derivatives - Google Patents

Vinblastine and leurocristine carboxamide derivatives

Info

Publication number
IL44415A
IL44415A IL44415A IL4441574A IL44415A IL 44415 A IL44415 A IL 44415A IL 44415 A IL44415 A IL 44415A IL 4441574 A IL4441574 A IL 4441574A IL 44415 A IL44415 A IL 44415A
Authority
IL
Israel
Prior art keywords
leurocristine
vinblastine
carboxamide derivatives
carboxamide
derivatives
Prior art date
Application number
IL44415A
Other languages
English (en)
Other versions
IL44415A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL44415A0 publication Critical patent/IL44415A0/xx
Publication of IL44415A publication Critical patent/IL44415A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL44415A 1973-04-02 1974-03-13 Vinblastine and leurocristine carboxamide derivatives IL44415A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (2)

Publication Number Publication Date
IL44415A0 IL44415A0 (en) 1974-06-30
IL44415A true IL44415A (en) 1978-08-31

Family

ID=23363051

Family Applications (1)

Application Number Title Priority Date Filing Date
IL44415A IL44415A (en) 1973-04-02 1974-03-13 Vinblastine and leurocristine carboxamide derivatives

Country Status (28)

Country Link
JP (2) JPS5919117B2 (xx)
AR (2) AR204004A1 (xx)
AT (1) AT340605B (xx)
BE (1) BE813168A (xx)
BG (3) BG21235A3 (xx)
CA (1) CA1042428A (xx)
CH (1) CH603669A5 (xx)
CS (1) CS185223B2 (xx)
CY (1) CY1044A (xx)
DD (1) DD113538A5 (xx)
DE (1) DE2415980A1 (xx)
DK (1) DK141511B (xx)
ES (2) ES424882A1 (xx)
FR (1) FR2223044B1 (xx)
GB (1) GB1463575A (xx)
HK (1) HK20180A (xx)
HU (1) HU171572B (xx)
IE (1) IE39071B1 (xx)
IL (1) IL44415A (xx)
KE (1) KE3028A (xx)
MY (1) MY8100025A (xx)
NL (1) NL181079C (xx)
PH (1) PH13623A (xx)
RO (2) RO77533A (xx)
SE (1) SE416206B (xx)
SU (4) SU731900A3 (xx)
YU (3) YU39719B (xx)
ZA (1) ZA741674B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (xx) * 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
LU83822A1 (fr) 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
CN101146532B (zh) 2005-01-21 2012-05-09 阿斯泰克斯治疗有限公司 药物化合物
ZA200800907B (en) 2005-07-18 2010-04-28 Bipar Sciences Inc Treatment of cancer
US7994222B2 (en) 2006-09-05 2011-08-09 Bipar Sciences, Inc. Monitoring of the inhibition of fatty acid synthesis by iodo-nitrobenzamide compounds
JP2010502730A (ja) 2006-09-05 2010-01-28 バイパー サイエンシズ，インコーポレイティド 癌の治療法
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
JP2011503111A (ja) 2007-11-12 2011-01-27 バイパー サイエンシズ，インコーポレイティド Ｐａｒｐ阻害剤単独又は抗腫瘍剤との組み合わせによる乳がんの治療
CN105121447B (zh) * 2013-04-19 2018-02-02 暨南大学 长春碱类衍生物及其制备方法和应用
CN113456797B (zh) * 2021-06-18 2024-03-08 暨南大学 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
YU39719B (en) 1985-04-30
IE39071B1 (en) 1978-08-02
YU39876B (en) 1985-04-30
NL181079C (nl) 1987-06-16
AR204004A1 (es) 1975-11-12
SU623522A3 (ru) 1978-09-05
CS185223B2 (en) 1978-09-15
BG21612A3 (xx) 1976-07-20
YU39875B (en) 1985-04-30
SU784783A3 (ru) 1980-11-30
FR2223044B1 (xx) 1978-06-30
RO73524B (ro) 1984-11-30
DE2415980A1 (de) 1974-10-10
JPS6033837B2 (ja) 1985-08-05
SU731900A3 (ru) 1980-04-30
JPS5919117B2 (ja) 1984-05-02
YU113880A (en) 1982-05-31
PH13623A (en) 1980-08-07
DE2415980C2 (xx) 1989-11-09
HK20180A (en) 1980-04-25
BG21235A3 (xx) 1976-03-20
NL7404423A (xx) 1974-10-04
RO77533A (ro) 1982-02-01
ATA267974A (de) 1977-04-15
YU81774A (en) 1982-05-31
IL44415A0 (en) 1974-06-30
FR2223044A1 (xx) 1974-10-25
MY8100025A (en) 1981-12-31
DK141511C (xx) 1980-09-29
CY1044A (en) 1980-08-01
ES424882A1 (es) 1976-12-16
RO73524A (ro) 1984-10-31
NL181079B (nl) 1987-01-16
AR203882A1 (es) 1975-10-31
DD113538A5 (xx) 1975-06-12
BG22831A3 (xx) 1977-04-20
SU652896A3 (ru) 1979-03-15
GB1463575A (en) 1977-02-02
IE39071L (en) 1974-10-02
JPS49128000A (xx) 1974-12-07
DK141511B (da) 1980-04-08
HU171572B (hu) 1978-02-28
ES446571A1 (es) 1977-06-16
YU113980A (en) 1982-05-31
CA1042428A (en) 1978-11-14
JPS59193895A (ja) 1984-11-02
AT340605B (de) 1977-12-27
CH603669A5 (xx) 1978-08-31
AU6671974A (en) 1975-09-18
KE3028A (en) 1980-03-28
SE416206B (sv) 1980-12-08
BE813168A (fr) 1974-10-02
ZA741674B (en) 1975-10-29

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