YU39876B - Process for obtaining new vinblastine derivatives - Google Patents

Process for obtaining new vinblastine derivatives

Info

Publication number
YU39876B
YU39876B YU1139/80A YU113980A YU39876B YU 39876 B YU39876 B YU 39876B YU 1139/80 A YU1139/80 A YU 1139/80A YU 113980 A YU113980 A YU 113980A YU 39876 B YU39876 B YU 39876B
Authority
YU
Yugoslavia
Prior art keywords
obtaining new
vinblastine derivatives
derivatives
new vinblastine
obtaining
Prior art date
Application number
YU1139/80A
Other languages
English (en)
Other versions
YU113980A (en
Inventor
G J Cullinan
K Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of YU113980A publication Critical patent/YU113980A/xx
Publication of YU39876B publication Critical patent/YU39876B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
YU1139/80A 1973-04-02 1980-04-25 Process for obtaining new vinblastine derivatives YU39876B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (2)

Publication Number Publication Date
YU113980A YU113980A (en) 1982-05-31
YU39876B true YU39876B (en) 1985-04-30

Family

ID=23363051

Family Applications (3)

Application Number Title Priority Date Filing Date
YU817/74A YU39719B (en) 1973-04-02 1974-03-25 Process for obtaining new derivatives of vinbastine and leurocristine
YU1139/80A YU39876B (en) 1973-04-02 1980-04-25 Process for obtaining new vinblastine derivatives
YU1138/80A YU39875B (en) 1973-04-02 1980-04-25 Process for obtaining new derivatives of vinblastine leurocristine and leurosidine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU817/74A YU39719B (en) 1973-04-02 1974-03-25 Process for obtaining new derivatives of vinbastine and leurocristine

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU1138/80A YU39875B (en) 1973-04-02 1980-04-25 Process for obtaining new derivatives of vinblastine leurocristine and leurosidine

Country Status (28)

Country Link
JP (2) JPS5919117B2 (xx)
AR (2) AR204004A1 (xx)
AT (1) AT340605B (xx)
BE (1) BE813168A (xx)
BG (3) BG21235A3 (xx)
CA (1) CA1042428A (xx)
CH (1) CH603669A5 (xx)
CS (1) CS185223B2 (xx)
CY (1) CY1044A (xx)
DD (1) DD113538A5 (xx)
DE (1) DE2415980A1 (xx)
DK (1) DK141511B (xx)
ES (2) ES424882A1 (xx)
FR (1) FR2223044B1 (xx)
GB (1) GB1463575A (xx)
HK (1) HK20180A (xx)
HU (1) HU171572B (xx)
IE (1) IE39071B1 (xx)
IL (1) IL44415A (xx)
KE (1) KE3028A (xx)
MY (1) MY8100025A (xx)
NL (1) NL181079C (xx)
PH (1) PH13623A (xx)
RO (2) RO77533A (xx)
SE (1) SE416206B (xx)
SU (4) SU731900A3 (xx)
YU (3) YU39719B (xx)
ZA (1) ZA741674B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (xx) * 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
LU83822A1 (fr) 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
CN101146532B (zh) 2005-01-21 2012-05-09 阿斯泰克斯治疗有限公司 药物化合物
ZA200800907B (en) 2005-07-18 2010-04-28 Bipar Sciences Inc Treatment of cancer
US7994222B2 (en) 2006-09-05 2011-08-09 Bipar Sciences, Inc. Monitoring of the inhibition of fatty acid synthesis by iodo-nitrobenzamide compounds
JP2010502730A (ja) 2006-09-05 2010-01-28 バイパー サイエンシズ,インコーポレイティド 癌の治療法
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
JP2011503111A (ja) 2007-11-12 2011-01-27 バイパー サイエンシズ,インコーポレイティド Parp阻害剤単独又は抗腫瘍剤との組み合わせによる乳がんの治療
CN105121447B (zh) * 2013-04-19 2018-02-02 暨南大学 长春碱类衍生物及其制备方法和应用
CN113456797B (zh) * 2021-06-18 2024-03-08 暨南大学 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
YU39719B (en) 1985-04-30
IE39071B1 (en) 1978-08-02
NL181079C (nl) 1987-06-16
AR204004A1 (es) 1975-11-12
SU623522A3 (ru) 1978-09-05
CS185223B2 (en) 1978-09-15
BG21612A3 (xx) 1976-07-20
YU39875B (en) 1985-04-30
SU784783A3 (ru) 1980-11-30
FR2223044B1 (xx) 1978-06-30
RO73524B (ro) 1984-11-30
DE2415980A1 (de) 1974-10-10
JPS6033837B2 (ja) 1985-08-05
SU731900A3 (ru) 1980-04-30
JPS5919117B2 (ja) 1984-05-02
YU113880A (en) 1982-05-31
PH13623A (en) 1980-08-07
DE2415980C2 (xx) 1989-11-09
HK20180A (en) 1980-04-25
BG21235A3 (xx) 1976-03-20
NL7404423A (xx) 1974-10-04
RO77533A (ro) 1982-02-01
ATA267974A (de) 1977-04-15
YU81774A (en) 1982-05-31
IL44415A0 (en) 1974-06-30
FR2223044A1 (xx) 1974-10-25
IL44415A (en) 1978-08-31
MY8100025A (en) 1981-12-31
DK141511C (xx) 1980-09-29
CY1044A (en) 1980-08-01
ES424882A1 (es) 1976-12-16
RO73524A (ro) 1984-10-31
NL181079B (nl) 1987-01-16
AR203882A1 (es) 1975-10-31
DD113538A5 (xx) 1975-06-12
BG22831A3 (xx) 1977-04-20
SU652896A3 (ru) 1979-03-15
GB1463575A (en) 1977-02-02
IE39071L (en) 1974-10-02
JPS49128000A (xx) 1974-12-07
DK141511B (da) 1980-04-08
HU171572B (hu) 1978-02-28
ES446571A1 (es) 1977-06-16
YU113980A (en) 1982-05-31
CA1042428A (en) 1978-11-14
JPS59193895A (ja) 1984-11-02
AT340605B (de) 1977-12-27
CH603669A5 (xx) 1978-08-31
AU6671974A (en) 1975-09-18
KE3028A (en) 1980-03-28
SE416206B (sv) 1980-12-08
BE813168A (fr) 1974-10-02
ZA741674B (en) 1975-10-29

Similar Documents

Publication Publication Date Title
YU36492B (en) Process for obtaining phenoxypropylamino derivatives
YU39876B (en) Process for obtaining new vinblastine derivatives
HU173540B (hu) Sposob poluchenija novykh proizvodnykh 5-oksa-prostaglandina
YU127874A (en) Process for obtaining compolyamides
YU182474A (en) Process for obtaining 7-hydroxy-5-methyl-isoflvone derivatives
YU36948B (en) Process for obtaining piperazinyl-quinazolines
YU39604B (en) Process for obtaining new 3-phenyl-6-halopyridazine
YU36980B (en) Process for obtaining new d-homosteroids
YU36931B (en) Process for obtaining 2-arylamino-2-imidazoline derivatives
YU309381A (en) Process for preparing new dibenzoxepine derivatives
YU287781A (en) Process for obtaining new naphthiridine derivatives
YU141474A (en) Process for obtaining triazolo-isoindole derivatives
YU25374A (en) Process for obtaining 6delta-deoxytetracyline
YU141374A (en) Process for obtaining triazolo-isoquinoline derivatives
YU148074A (en) Process for obtaining new thiazlo-isoquinoline derivatives
YU36922B (en) Process for obtaining new m-diurethanes
YU36926B (en) Process for obtaining new aminopyrrol derivatives
YU35893B (en) Process for obtaining novel leurosine derivatives
YU41552B (en) Process for producang new triazdine derivatives
YU335774A (en) Process for obtaining pyrimidino-aminoethyl-ergoline derivatives
YU36941B (en) Process for obtaining new thiadizolyl-carbamides
YU279774A (en) Process for obtaining 4-oxo-2-imidazolidinylidene-urea
YU36520B (en) Process for obtaining new thiadiazolylimidazolidinones
YU114274A (en) Process for obtaining substituted phenyl-n-alkyl-carbamates
YU36009B (en) Process for obtaining 4-acetamido-phenyl-2-acetoxybenzoate