CH603669A5 - - Google Patents

Info

Publication number
CH603669A5
CH603669A5 CH446374A CH446374A CH603669A5 CH 603669 A5 CH603669 A5 CH 603669A5 CH 446374 A CH446374 A CH 446374A CH 446374 A CH446374 A CH 446374A CH 603669 A5 CH603669 A5 CH 603669A5
Authority
CH
Switzerland
Application number
CH446374A
Inventor
George Joseph Cullinan
Koert Gerzon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CH603669A5 publication Critical patent/CH603669A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH446374A 1973-04-02 1974-03-29 CH603669A5 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34727573A 1973-04-02 1973-04-02

Publications (1)

Publication Number Publication Date
CH603669A5 true CH603669A5 (enExample) 1978-08-31

Family

ID=23363051

Family Applications (1)

Application Number Title Priority Date Filing Date
CH446374A CH603669A5 (enExample) 1973-04-02 1974-03-29

Country Status (28)

Country Link
JP (2) JPS5919117B2 (enExample)
AR (2) AR204004A1 (enExample)
AT (1) AT340605B (enExample)
BE (1) BE813168A (enExample)
BG (3) BG21612A3 (enExample)
CA (1) CA1042428A (enExample)
CH (1) CH603669A5 (enExample)
CS (1) CS185223B2 (enExample)
CY (1) CY1044A (enExample)
DD (1) DD113538A5 (enExample)
DE (1) DE2415980A1 (enExample)
DK (1) DK141511B (enExample)
ES (2) ES424882A1 (enExample)
FR (1) FR2223044B1 (enExample)
GB (1) GB1463575A (enExample)
HK (1) HK20180A (enExample)
HU (1) HU171572B (enExample)
IE (1) IE39071B1 (enExample)
IL (1) IL44415A (enExample)
KE (1) KE3028A (enExample)
MY (1) MY8100025A (enExample)
NL (1) NL181079C (enExample)
PH (1) PH13623A (enExample)
RO (2) RO73524B (enExample)
SE (1) SE416206B (enExample)
SU (4) SU731900A3 (enExample)
YU (3) YU39719B (enExample)
ZA (1) ZA741674B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (enExample) * 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30560E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4203898A (en) 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
US4210584A (en) 1979-01-15 1980-07-01 Eli Lilly And Company Vindesine synthesis
US4357334A (en) 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
LU83822A1 (fr) * 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules
AU2006207321B2 (en) 2005-01-21 2012-09-06 Astex Therapeutics Limited Pharmaceutical compounds
US7405227B2 (en) 2005-07-18 2008-07-29 Bipar Sciences, Inc. Treatment of cancer
CN101534836B (zh) 2006-09-05 2011-09-28 彼帕科学公司 Parp抑制剂在制备治疗肥胖症的药物中的用途
WO2008030883A2 (en) 2006-09-05 2008-03-13 Bipar Sciences, Inc. Treatment of cancer
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
EP2217227B1 (en) 2007-11-12 2013-08-21 BiPar Sciences, Inc. Treatment of breast cancer with 4-iodo-3-nitrobenzamide in combination with anti-tumor agents
JP6250710B2 (ja) * 2013-04-19 2017-12-20 曁南大学 ビンブラスチン誘導体の調製方法
CN113456797B (zh) * 2021-06-18 2024-03-08 暨南大学 长春碱类衍生物在制备治疗骨肉瘤和/或软组织肉瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine

Also Published As

Publication number Publication date
JPS59193895A (ja) 1984-11-02
BE813168A (fr) 1974-10-02
BG21235A3 (bg) 1976-03-20
YU39719B (en) 1985-04-30
IL44415A (en) 1978-08-31
RO73524A (ro) 1984-10-31
ES424882A1 (es) 1976-12-16
KE3028A (en) 1980-03-28
HU171572B (hu) 1978-02-28
YU113880A (en) 1982-05-31
YU39876B (en) 1985-04-30
FR2223044B1 (enExample) 1978-06-30
SU623522A3 (ru) 1978-09-05
NL181079C (nl) 1987-06-16
AR203882A1 (es) 1975-10-31
SU652896A3 (ru) 1979-03-15
AR204004A1 (es) 1975-11-12
RO77533A (ro) 1982-02-01
AT340605B (de) 1977-12-27
SE416206B (sv) 1980-12-08
FR2223044A1 (enExample) 1974-10-25
BG22831A3 (bg) 1977-04-20
CS185223B2 (en) 1978-09-15
RO73524B (ro) 1984-11-30
AU6671974A (en) 1975-09-18
IE39071B1 (en) 1978-08-02
JPS5919117B2 (ja) 1984-05-02
CY1044A (en) 1980-08-01
DD113538A5 (enExample) 1975-06-12
YU81774A (en) 1982-05-31
GB1463575A (en) 1977-02-02
ZA741674B (en) 1975-10-29
SU731900A3 (ru) 1980-04-30
SU784783A3 (ru) 1980-11-30
DK141511C (enExample) 1980-09-29
JPS6033837B2 (ja) 1985-08-05
DK141511B (da) 1980-04-08
IL44415A0 (en) 1974-06-30
DE2415980A1 (de) 1974-10-10
PH13623A (en) 1980-08-07
YU113980A (en) 1982-05-31
JPS49128000A (enExample) 1974-12-07
DE2415980C2 (enExample) 1989-11-09
ES446571A1 (es) 1977-06-16
HK20180A (en) 1980-04-25
YU39875B (en) 1985-04-30
CA1042428A (en) 1978-11-14
NL181079B (nl) 1987-01-16
NL7404423A (enExample) 1974-10-04
BG21612A3 (bg) 1976-07-20
MY8100025A (en) 1981-12-31
ATA267974A (de) 1977-04-15
IE39071L (en) 1974-10-02

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Legal Events

Date Code Title Description
PL Patent ceased
SPCF Supplementary protection certificate filed

Free format text: IKS 42863, 951024

SPCG Supplementary protection certificate granted

Free format text: IKS 42863/820316, 951024, EXPIRES:19970316

PL Patent ceased