KE3002A - Purine compounds and salts thereof - Google Patents

Purine compounds and salts thereof

Info

Publication number
KE3002A
KE3002A KE3002A KE300279A KE3002A KE 3002 A KE3002 A KE 3002A KE 3002 A KE3002 A KE 3002A KE 300279 A KE300279 A KE 300279A KE 3002 A KE3002 A KE 3002A
Authority
KE
Kenya
Prior art keywords
salts
purine compounds
purine
compounds
Prior art date
Application number
KE3002A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10402412&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KE3002(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of KE3002A publication Critical patent/KE3002A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
KE3002A 1974-09-02 1979-11-13 Purine compounds and salts thereof KE3002A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB38278/74A GB1523865A (en) 1974-09-02 1974-09-02 Purine compunds and salts thereof

Publications (1)

Publication Number Publication Date
KE3002A true KE3002A (en) 1979-12-14

Family

ID=10402412

Family Applications (1)

Application Number Title Priority Date Filing Date
KE3002A KE3002A (en) 1974-09-02 1979-11-13 Purine compounds and salts thereof

Country Status (35)

Country Link
US (3) US4323573A (fr)
JP (1) JPS5154589A (fr)
AR (4) AR220299A1 (fr)
AT (1) AT354462B (fr)
AU (1) AU503160B2 (fr)
BE (1) BE833006A (fr)
BG (4) BG26536A4 (fr)
CA (1) CA1062257A (fr)
CH (7) CH626363A5 (fr)
CS (2) CS203092B2 (fr)
CY (1) CY1033A (fr)
DD (1) DD122092A5 (fr)
DE (1) DE2539963C2 (fr)
DK (1) DK146595C (fr)
ES (3) ES440631A1 (fr)
FI (1) FI60709C (fr)
FR (1) FR2282892A1 (fr)
GB (1) GB1523865A (fr)
HK (1) HK84379A (fr)
HU (1) HU176730B (fr)
IE (1) IE42282B1 (fr)
IL (1) IL48035A (fr)
KE (1) KE3002A (fr)
LU (1) LU73304A1 (fr)
MC (1) MC1068A1 (fr)
MY (1) MY8200191A (fr)
NL (1) NL175061C (fr)
NO (1) NO144216C (fr)
NZ (1) NZ178556A (fr)
RO (4) RO76939A (fr)
SE (1) SE428562C (fr)
SU (7) SU904523A3 (fr)
YU (4) YU39947B (fr)
ZA (1) ZA755574B (fr)
ZM (1) ZM12875A1 (fr)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146715A (en) 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
US4060616A (en) * 1976-03-01 1977-11-29 Burroughs Wellcome Co. Purine derivatives with repeating unit
AU521577B2 (en) * 1977-02-24 1982-04-22 Wellcome Foundation Limited, The 9-hydroxyethoxymethyl guanine phosphates
US4287188A (en) 1977-02-24 1981-09-01 Burroughs Wellcome Co. Purine derivatives
KR830005852A (ko) * 1980-07-18 1983-09-14 미첼 페터 잭슨 피부와 점막의 비루스 감염치료에 적합한 국소치료제의 제조방법
US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
US5157120A (en) * 1980-09-16 1992-10-20 Syntex (U.S.A.) Inc. Guanine derivatives
AU547311B2 (en) * 1980-10-15 1985-10-17 Wellcome Foundation Limited, The Treating viral infections in fish
US4603219A (en) * 1981-05-21 1986-07-29 Syntex (U.S.A.) Inc. 1,3-dibenzyloxy-2-acetoxymethoxypropane, intermediate for 9-(1,3-dihydroxy-2-propoxymethyl)guanine
US4355032B2 (en) * 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
US4423050A (en) * 1981-05-21 1983-12-27 Syntex (U.S.A.) Inc. 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent
ES8403128A1 (es) * 1981-08-11 1983-10-01 Wellcome Found "un procedimiento para preparar derivados de purina".
AU564576B2 (en) * 1981-09-24 1987-08-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Purine derivatives
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
MC1585A1 (fr) * 1982-02-12 1985-02-22 Ens Bio Logicals Inc Procede de fabrication de compositions antivirales
SE8203855D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine i
SE8203856D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine ii
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
US4649140A (en) * 1982-10-14 1987-03-10 Burroughs Wellcome Co. Purine derivatives
US5059604A (en) * 1982-10-14 1991-10-22 Burroughs Wellcome Co. 2-amino purine derivatives
US4745119A (en) * 1982-10-14 1988-05-17 Burroughs Wellcome Co. Method for using purine derivatives
US4609662A (en) * 1982-10-14 1986-09-02 Burroughs Wellcome Co. Method for using purine derivatives
AU573540B2 (en) * 1982-10-14 1988-06-16 Wellcome Foundation Limited, The 6-hydrogen purine derivatives
US4612314A (en) * 1982-12-22 1986-09-16 Syntex (U.S.A.) Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4461757A (en) * 1983-02-23 1984-07-24 Ens Bio Logicals Inc. Dimethylaminomethylenated anti-herpes compounds
ES520140A0 (es) * 1983-02-25 1984-04-01 Ind Farma Especial Un procedimiento para la preparacion de acicloguanosina.
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
US4557934A (en) 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
JPS6023380A (ja) * 1983-06-24 1985-02-05 メルク・エンド・カムパニー・インコーポレーテッド 抗ウイルス剤
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
US4897479A (en) * 1983-09-30 1990-01-30 Merck & Co., Inc. Arylsulfonyloxy purine intermediates
JPS6094992A (ja) * 1983-10-28 1985-05-28 Sankyo Co Ltd グリゼオ−ル酸誘導体
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
ZA848080B (en) * 1983-10-31 1985-06-26 Warner Lambert Co Purine derivatives
US4918219A (en) * 1983-10-31 1990-04-17 Warner-Lambert Company Glycerine derivatives
US4806642A (en) * 1984-10-05 1989-02-21 Warner-Lambert Company Purine derivatives
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
US4617304A (en) * 1984-04-10 1986-10-14 Merck & Co., Inc. Purine derivatives
IL74881A0 (en) * 1984-04-13 1985-07-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
JPH0625061B2 (ja) 1984-07-03 1994-04-06 ザ ウエルカム フアウンデ−シヨン リミテツド 抗ウイルス性化合物
EP0190123A1 (fr) * 1984-07-20 1986-08-13 GAUNTT, Charles, O. Compose immunoregulateur et anti-viral
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5683990A (en) * 1985-03-16 1997-11-04 Glaxo Wellcome Inc. Treatment of human viral infections
CS263951B1 (en) * 1985-04-25 1989-05-12 Antonin Holy 9-(phosponylmethoxyalkyl)adenines and method of their preparation
CS263952B1 (en) * 1985-04-25 1989-05-12 Holy Antonin Remedy with antiviral effect
IL78643A0 (en) * 1985-05-02 1986-08-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
EP0203736B1 (fr) 1985-05-02 1989-11-23 The Wellcome Foundation Limited Composés antiviraux
DE3529497A1 (de) * 1985-08-17 1987-02-26 Boehringer Mannheim Gmbh N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
IT1207507B (it) * 1985-10-21 1989-05-25 Baldacci Lab Spa Coniugato della 9-(2-idrossietossimetil)guanina con albumina umana lattosaminata, procedimento per la sua preparazione e composizioni farmaceutiche che la contengono.
WO1988002258A1 (fr) * 1986-10-06 1988-04-07 The University Of Virginia Alumni Patents Foundati Utilisation d'une solution contenant de l'adenosine, de l'hypoxanthine et du ribose pour ameliorer la protection du coeur au cours d'une operation chirurgicale
EP0290630A4 (fr) * 1986-11-25 1990-02-26 Inst Organicheskogo Sinteza Ak Guanines substitutees en position 9.
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
US4829055A (en) * 1987-01-23 1989-05-09 Naficy Sadeque S Method of treatment for herpes infections of external tissues
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US4835104A (en) * 1987-06-16 1989-05-30 Ajinomoto Co., Inc., Patent & Licensing Department Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
US6306647B1 (en) 1987-06-16 2001-10-23 Ajinomoto Co., Inc. Process for producing and purifying 2′,3′-dideoxynucleosides, and process for producing 2′,3′-dideoxy-2′,3′-didehydronucleosides
GB8719367D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Therapeutic compounds
GB8725939D0 (en) * 1987-11-05 1987-12-09 Wellcome Found Therapeutic compounds
CA1302887C (fr) * 1987-11-24 1992-06-09 Yves Langelier Melange d'acyclovir (ou d'un de ses devises) et de bacitracine
JPH01121424U (fr) * 1988-02-10 1989-08-17
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
US5164395A (en) * 1988-06-27 1992-11-17 Burroughs Wellcome Co. Antiviral acetyl pyridine derivative or said acetyl pyridine derivative in combination with acyclovir
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
DE68907013D1 (de) * 1988-10-24 1993-07-15 Wellcome Found Guaninderivate mit antiviraler wirkung und deren pharmazeutisch vertraegliche salze.
KR910700253A (ko) * 1989-01-31 1991-03-14 로버트 제이, 바란 N_6-치환-9-메틸아데닌: 신규한 부류의 아데노신 수용체 길항질
US4966895A (en) * 1989-02-02 1990-10-30 Merck & Co. Inc. Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
GB8907173D0 (en) * 1989-03-30 1989-05-10 Beecham Group Plc Novel compounds
GB8912043D0 (en) * 1989-05-25 1989-07-12 Beecham Group Plc Novel compounds
GB9001886D0 (en) * 1990-01-26 1990-03-28 Beecham Group Plc Pharmaceutical formulation
DE4008858A1 (de) * 1990-03-20 1991-09-26 Hoechst Ag Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
CA2033447C (fr) * 1990-12-31 1999-08-31 Robert Deziel Complexe synergique pour le traitement des infections herpetiques
US5879700A (en) * 1991-10-15 1999-03-09 Hostetler; Karl Y. Nucleoside analogue phosphates for topical use
US5580571A (en) * 1991-10-15 1996-12-03 Hostetler; Karl Y. Nucleoside analogues
CA2091732C (fr) * 1992-07-08 1998-07-21 Anica Markovac Procede pour la preparation de 2-fluoro-9-(2,3,5-tri-o-benzyl-beta-d-arabinofuranosyl)adenine
DK169121B1 (da) 1992-09-09 1994-08-22 Gea Farmaceutisk Fabrik As Antiviralt virksom farmaceutisk olie-i-vand-emulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf
DE59310344D1 (de) * 1992-09-24 2003-07-24 Hoechst Ag N1-Substituierte 1H-1,2,3-Triazolo[4,5-d]pyrimidine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als antivirale Mittel
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
US6015573A (en) * 1993-05-12 2000-01-18 Hostetler; Karl Y. Nucleoside phosphate therapy for viral infection
IT1264599B1 (it) * 1993-06-14 1996-10-04 Solar Chem Sa Processo per la sintesi della 9-(2-idrossietossimetil)- guanina
US5567816A (en) * 1994-07-26 1996-10-22 Syntex (U.S.A.) Inc. Preparation of acyclovir using 1,3 dioxolane
US5856481A (en) * 1994-07-28 1999-01-05 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
US5565565A (en) * 1994-08-04 1996-10-15 Syntex (U.S.A.) Inc. Preparation of N-9 substituted guanine compounds
US5627185A (en) * 1994-11-23 1997-05-06 Gosselin; Gilles Acyclovir derivatives as antiviral agents
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
IN179493B (fr) * 1996-02-22 1997-10-11 Lupin Laboraties Ltd
US5789589A (en) * 1996-04-22 1998-08-04 Drug Innovation & Design, Inc. Guanine analog phosphates
US6440980B1 (en) 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
WO1998051692A1 (fr) * 1997-05-15 1998-11-19 Drug Innovation & Design, Inc. Derives diesters d'acyclovir
US6180790B1 (en) 1997-05-15 2001-01-30 Drug Innovation And Design, Inc. Methods of preparing acyclovir prodrugs
EA200400535A1 (ru) * 2001-10-16 2005-06-30 Аванир Фармасютикалз ПОДАВЛЕНИЕ ВИРУСОВ n-ДОКОСАНОЛОМ
US20070129334A1 (en) * 2001-10-30 2007-06-07 Conforma Therapeutics Corporation Orally Active Purine-Based Inhibitors of Heat Shock Protein 90
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ATE398455T1 (de) 2003-01-14 2008-07-15 Gilead Sciences Inc Zusammensetzungen und verfahren zur antiviralen kombinationstherapie
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TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
EP2001488A4 (fr) * 2006-03-14 2009-11-25 Alt Solutions Inc Prevention et traitement des cancers et d'autres maladies
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
WO2010075517A2 (fr) 2008-12-23 2010-07-01 Pharmasset, Inc. Analogues de nucléoside
CL2009002207A1 (es) 2008-12-23 2011-02-18 Gilead Pharmasset Llc Compuestos derivados de 3-hidroxi-5-(9h-purin-9-il)tetrahidrofuran-2-il, inhibidor de la replicacion de arn viral dependiente de arn; composicion farmaceutica; uso para el tratamiento de hepatitis c.
SG172363A1 (en) 2008-12-23 2011-07-28 Pharmasset Inc Synthesis of purine nucleosides
AP3515A (en) 2010-03-31 2016-01-11 Gilead Pharmasset Llc Nucleoside phosphoramidates
GB201819418D0 (en) 2018-11-29 2019-01-16 Daniel Calladine Ltd Anti-viral compositions
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines

Also Published As

Publication number Publication date
HK84379A (en) 1979-12-14
SU904523A3 (ru) 1982-02-07
US4323573A (en) 1982-04-06
CH629206A5 (de) 1982-04-15
LU73304A1 (fr) 1976-08-13
ES440631A1 (es) 1977-06-16
SE428562C (sv) 1985-11-18
CY1033A (en) 1980-08-01
ATA676375A (de) 1979-06-15
NZ178556A (en) 1978-09-25
FR2282892B1 (fr) 1980-04-25
NL175061C (nl) 1984-09-17
DK146595C (da) 1984-04-24
CH626363A5 (fr) 1981-11-13
DK392675A (da) 1976-03-03
YU40079B (en) 1985-06-30
CA1062257A (fr) 1979-09-11
NO753009L (fr) 1976-03-03
US4360522A (en) 1982-11-23
IE42282L (en) 1976-03-02
GB1523865A (en) 1978-09-06
SU700064A3 (ru) 1979-11-25
YU120182A (en) 1982-08-31
RO76939A (fr) 1981-06-22
BG25094A3 (en) 1978-07-12
DD122092A5 (fr) 1976-09-12
DE2539963A1 (de) 1976-03-18
CS203092B2 (en) 1981-02-27
CH623587A5 (fr) 1981-06-15
YU39947B (en) 1985-06-30
CH626364A5 (fr) 1981-11-13
NO144216C (no) 1981-07-15
YU119982A (en) 1982-08-31
YU120082A (en) 1982-08-31
FR2282892A1 (fr) 1976-03-26
CH629805A5 (de) 1982-05-14
BE833006A (fr) 1976-03-02
CH623586A5 (fr) 1981-06-15
SU751325A3 (ru) 1980-07-23
ES455979A1 (es) 1978-01-16
AU8445975A (en) 1977-03-10
BG26536A4 (bg) 1979-04-12
MY8200191A (en) 1982-12-31
AT354462B (de) 1979-01-10
YU222075A (en) 1982-08-31
CS203093B2 (en) 1981-02-27
SE428562B (sv) 1983-07-11
SE7509675L (sv) 1976-03-03
ZM12875A1 (en) 1977-09-21
AU503160B2 (en) 1979-08-23
DE2539963C2 (de) 1987-01-22
IL48035A0 (en) 1975-11-25
FI60709B (fi) 1981-11-30
JPS5154589A (en) 1976-05-13
US4294831A (en) 1981-10-13
AR212914A1 (es) 1978-11-15
YU40080B (en) 1985-06-30
FI60709C (fi) 1982-03-10
RO74274A (fr) 1981-09-24
BG26389A3 (bg) 1979-03-15
DK146595B (da) 1983-11-14
ES455978A1 (es) 1978-01-16
RO74276A (fr) 1981-06-26
SU858569A3 (ru) 1981-08-23
SU799664A3 (ru) 1981-01-23
BG24815A3 (en) 1978-05-12
SU784777A3 (ru) 1980-11-30
AR220885A1 (es) 1980-12-15
AR220299A1 (es) 1980-10-31
NO144216B (no) 1981-04-06
FI752465A (fr) 1976-03-03
NL7510342A (nl) 1976-03-04
MC1068A1 (fr) 1976-05-21
ZA755574B (en) 1977-04-27
SU686618A3 (ru) 1979-09-15
HU176730B (en) 1981-04-28
IL48035A (en) 1981-07-31
AR220508A1 (es) 1980-11-14
CH628897A5 (de) 1982-03-31
NL175061B (nl) 1984-04-16
IE42282B1 (en) 1980-07-16
JPS6147839B2 (fr) 1986-10-21
RO74275A (fr) 1981-09-24

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