JPWO2022020714A5 - - Google Patents
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- Publication number
- JPWO2022020714A5 JPWO2022020714A5 JP2023504724A JP2023504724A JPWO2022020714A5 JP WO2022020714 A5 JPWO2022020714 A5 JP WO2022020714A5 JP 2023504724 A JP2023504724 A JP 2023504724A JP 2023504724 A JP2023504724 A JP 2023504724A JP WO2022020714 A5 JPWO2022020714 A5 JP WO2022020714A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- heteroaryl
- heterocycloalkyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063056165P | 2020-07-24 | 2020-07-24 | |
| US63/056,165 | 2020-07-24 | ||
| US202063113555P | 2020-11-13 | 2020-11-13 | |
| US63/113,555 | 2020-11-13 | ||
| PCT/US2021/042960 WO2022020714A1 (en) | 2020-07-24 | 2021-07-23 | Thiophene hsd17b13 inhibitors and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023537271A JP2023537271A (ja) | 2023-08-31 |
| JPWO2022020714A5 true JPWO2022020714A5 (https=) | 2024-07-18 |
| JP2023537271A5 JP2023537271A5 (https=) | 2024-07-18 |
Family
ID=79729016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023504724A Pending JP2023537271A (ja) | 2020-07-24 | 2021-07-23 | チオフェンｈｓｄ１７ｂ１３阻害剤とその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230278978A1 (https=) |
| EP (1) | EP4185381A4 (https=) |
| JP (1) | JP2023537271A (https=) |
| CN (1) | CN116323578A (https=) |
| TW (1) | TW202220967A (https=) |
| WO (1) | WO2022020714A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116670118B (zh) | 2020-11-13 | 2026-02-06 | 伊尼制药公司 | 二氯苯酚hsd17b13抑制剂及其用途 |
| EP4320111A4 (en) * | 2021-04-05 | 2025-03-12 | Inipharm, Inc. | HYDROXYPYRIDINE-TYPE HSD17B13 INHIBITORS AND USES THEREOF |
| CN118103038A (zh) | 2021-08-20 | 2024-05-28 | 英安塔制药有限公司 | 17β-羟基类固醇脱氢酶13型抑制剂及其使用方法 |
| JP2024546946A (ja) * | 2021-12-15 | 2024-12-26 | ブリストル－マイヤーズ スクイブ カンパニー | ベンゾチオフェンｒｘｆｐ１アゴニスト |
| JP2025503953A (ja) * | 2022-01-26 | 2025-02-06 | イニファーム，インク． | ２－置換チアゾールｈｓｄ１７ｂ１３阻害剤およびその使用 |
| DK4514782T3 (da) | 2022-05-19 | 2025-12-15 | Astrazeneca Ab | Heteroaromatiske amidoforbindelser, der er nyttige ved behandling af leversygdomme |
| JP2025523357A (ja) | 2022-06-09 | 2025-07-23 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｈｓｄ１７ｂ１３阻害剤 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19642451A1 (de) * | 1996-10-15 | 1998-04-16 | Merck Patent Gmbh | Aminothiophencarbonsäureamide |
| WO2004085382A1 (ja) * | 2003-03-27 | 2004-10-07 | Kirin Beer Kabushiki Kaisha | 生体内リン輸送を阻害する化合物およびそれを含んでなる医薬 |
| EP1806347A4 (en) * | 2004-10-08 | 2009-07-01 | Astellas Pharma Inc | PYRIMIDINE DERIVATIVES FUSED WITH AN AROMATIC RING |
| GB0513702D0 (en) * | 2005-07-04 | 2005-08-10 | Sterix Ltd | Compound |
| CN101287728A (zh) * | 2005-08-17 | 2008-10-15 | 先灵公司 | 新的高亲和力噻吩基和呋喃基激酶配体 |
| SI2588475T1 (sl) * | 2010-07-02 | 2015-12-31 | Gilead Sciences, Inc. | Kinazni inhibitorji za regulacijo apoptoznega signala |
| US20140057953A1 (en) * | 2011-03-03 | 2014-02-27 | Rolf Hartmann | Biaryl derivatives as selective 17beta-hydroxysteroid dehydrogenase type 2 inhibitors |
| WO2013165606A1 (en) * | 2012-05-04 | 2013-11-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Modulators of the relaxin receptor 1 |
| CN105524053B (zh) * | 2014-10-19 | 2020-06-05 | 广东东阳光药业有限公司 | 四氢苯并噻吩化合物 |
| DK3356345T3 (da) * | 2015-09-30 | 2024-02-12 | Max Planck Gesellschaft | Heteroaryl-derivater som sepiapterin-reduktase-inhibitorer |
| KR101870968B1 (ko) * | 2016-02-02 | 2018-06-25 | 부산대학교 산학협력단 | Ppar, fxr 및 ampk 활성화 효능을 갖는 신규 티오펜 화합물 또는 이의 약제학적으로 허용 가능한 염 및 이의 의학적 용도 |
| SI3497091T1 (sl) * | 2016-08-15 | 2020-11-30 | Eli Lilly And Company | Kondenzirani derivati tiofena uporabni kot inhibitorji NAPI-IIB |
| TWI762634B (zh) * | 2017-05-05 | 2022-05-01 | 大陸商上海赫普化醫藥技術有限公司 | 胺基-芳基-苯甲醯胺化合物及其使用方法 |
| BR112020015743A2 (pt) * | 2018-02-08 | 2020-12-15 | Enyo Pharma | Derivados de tiofeno não fundido e seus usos |
| AU2019240214A1 (en) * | 2018-03-21 | 2020-09-17 | Ionis Pharmaceuticals, Inc. | Modulation of HSD17B13 expression |
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2021
- 2021-07-23 WO PCT/US2021/042960 patent/WO2022020714A1/en not_active Ceased
- 2021-07-23 TW TW110127231A patent/TW202220967A/zh unknown
- 2021-07-23 CN CN202180065663.XA patent/CN116323578A/zh active Pending
- 2021-07-23 JP JP2023504724A patent/JP2023537271A/ja active Pending
- 2021-07-23 EP EP21846586.2A patent/EP4185381A4/en active Pending
- 2021-07-23 US US18/006,059 patent/US20230278978A1/en active Pending