|
US4166452A
(en)
|
1976-05-03 |
1979-09-04 |
Generales Constantine D J Jr |
Apparatus for testing human responses to stimuli
|
|
US4256108A
(en)
|
1977-04-07 |
1981-03-17 |
Alza Corporation |
Microporous-semipermeable laminated osmotic system
|
|
US4265874A
(en)
|
1980-04-25 |
1981-05-05 |
Alza Corporation |
Method of delivering drug with aid of effervescent activity generated in environment of use
|
|
LU86084A1
(fr)
|
1985-09-20 |
1987-04-02 |
Faco Sa |
Apparei de massage electrique
|
|
US5102417A
(en)
|
1985-11-07 |
1992-04-07 |
Expandable Grafts Partnership |
Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
|
|
US4800882A
(en)
|
1987-03-13 |
1989-01-31 |
Cook Incorporated |
Endovascular stent and delivery system
|
|
US4886062A
(en)
|
1987-10-19 |
1989-12-12 |
Medtronic, Inc. |
Intravascular radially expandable stent and method of implant
|
|
WO1990013332A1
(en)
|
1989-05-11 |
1990-11-15 |
Cedars-Sinai Medical Center |
Stent with sustained drug delivery
|
|
CA2049973C
(en)
|
1990-02-28 |
2002-12-24 |
Rodney G. Wolff |
Intralumenal drug eluting prosthesis
|
|
US5429634A
(en)
|
1993-09-09 |
1995-07-04 |
Pdt Systems |
Biogenic implant for drug delivery and method
|
|
US5419760A
(en)
|
1993-01-08 |
1995-05-30 |
Pdt Systems, Inc. |
Medicament dispensing stent for prevention of restenosis of a blood vessel
|
|
US6774278B1
(en)
|
1995-06-07 |
2004-08-10 |
Cook Incorporated |
Coated implantable medical device
|
|
US5833651A
(en)
|
1996-11-08 |
1998-11-10 |
Medtronic, Inc. |
Therapeutic intraluminal stents
|
|
US6166050A
(en)
|
1998-12-14 |
2000-12-26 |
American Home Products Corporation |
3,4-diamino-3-cyclobutene-1,2-dione derivatives which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6294192B1
(en)
|
1999-02-26 |
2001-09-25 |
Lipocine, Inc. |
Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
|
|
AR033803A1
(es)
|
2000-03-01 |
2004-01-07 |
Smithkline Beecham Corp |
Compuestos de dianilino escuarano, composiciones farmaceuticas que los comprenden, y el uso de los mismos en la fabricacion de medicamentos para tratar enfermedades mediadas por quimioquinas
|
|
MXPA02011868A
(es)
|
2000-05-30 |
2003-04-10 |
Smithkline Beecham Corp |
Antagonistas de receptor de interleucina 8.
|
|
US20040048897A1
(en)
|
2001-01-16 |
2004-03-11 |
Mccleland Brent |
Il-8 receptor antagonists
|
|
DE60230722D1
(de)
|
2001-01-16 |
2009-02-26 |
Smithkline Beecham Corp |
Il-8-rezeptor-antagonisten
|
|
RU2003126913A
(ru)
|
2001-02-02 |
2005-03-10 |
Шеринг Корпорейшн (US) |
3,4-дизамещенные циклобутен-1,2-дионы, как антагонисты хемокинового рецептора схс
|
|
US20030204085A1
(en)
|
2001-02-02 |
2003-10-30 |
Taveras Arthur G. |
3, 4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor antagonists
|
|
US7132445B2
(en)
|
2001-04-16 |
2006-11-07 |
Schering Corporation |
3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
|
|
US20040097547A1
(en)
|
2001-04-16 |
2004-05-20 |
Taveras Arthur G. |
3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
|
|
US20040106794A1
(en)
|
2001-04-16 |
2004-06-03 |
Schering Corporation |
3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
|
|
PL208928B1
(pl)
|
2001-04-16 |
2011-06-30 |
Pharmacopeia |
3, 4-di-podstawione cyklobuten-1, 2-diony jako ligandy receptora CXC chemokiny
|
|
US20040053953A1
(en)
|
2002-03-18 |
2004-03-18 |
Schering Corporation |
Treatment of chemokine mediated diseases
|
|
US6770729B2
(en)
|
2002-09-30 |
2004-08-03 |
Medtronic Minimed, Inc. |
Polymer compositions containing bioactive agents and methods for their use
|
|
CN101514193B
(zh)
|
2003-04-18 |
2012-12-19 |
默沙东公司 |
呋喃取代的二氧代环丁烯的合成
|
|
AU2005210504B2
(en)
|
2004-01-30 |
2009-01-08 |
Merck Sharp & Dohme Corp. |
Crystalline polymorphs of a CXC-chemokine receptor ligand
|
|
US7521457B2
(en)
|
2004-08-20 |
2009-04-21 |
Boehringer Ingelheim International Gmbh |
Pyrimidines as PLK inhibitors
|
|
GB0419481D0
(en)
|
2004-09-02 |
2004-10-06 |
Cancer Rec Tech Ltd |
Isoindolin-1-one derivatives
|
|
DE102005035742A1
(de)
|
2005-07-29 |
2007-02-01 |
Merck Patent Gmbh |
Quadratsäurederivate II
|
|
AR061829A1
(es)
|
2006-07-07 |
2008-09-24 |
Schering Corp |
Ciclobuten-1, 2-dionas 3,4-di sustituidas como ligandos de receptores de quimiocinas cxc
|
|
AU2008223348A1
(en)
|
2007-03-07 |
2008-09-12 |
Alantos Pharmaceuticals Holding, Inc. |
Metalloprotease inhibitors containing a heterocyclic moiety
|
|
ES2386489T3
(es)
|
2007-06-06 |
2012-08-21 |
Novartis Ag |
Compuestos ciclobutanediona sustituidos anti-inflamatorios
|
|
WO2009005801A1
(en)
|
2007-07-03 |
2009-01-08 |
Schering Corporation |
Process and intermediates for the synthesis of 1,2-substituted 3,4-dioxo-1-cyclobutene compounds
|
|
WO2009005802A1
(en)
|
2007-07-05 |
2009-01-08 |
Schering Corporation |
Process for controlled crystal size in 1,2-substituted 3,4-dioxo-1-cyclobutene compounds
|
|
WO2009012375A2
(en)
|
2007-07-19 |
2009-01-22 |
Wyeth |
Squarate kinase inhibitors
|
|
US20100267712A1
(en)
|
2007-09-27 |
2010-10-21 |
The United States of America, as represented by the Secretary, Department of Health and |
Isoindoline compounds for the treatment of spinal muscular atrophy and other uses
|
|
US20110009482A1
(en)
|
2007-12-04 |
2011-01-13 |
Schering Corporation |
Methods of treating copd
|
|
RU2529468C2
(ru)
|
2008-06-24 |
2014-09-27 |
Топотаргет А/С |
Производные 1, 2-дигидроциклобутендиона в качестве ингибиторов фосфорибозилтрансферазы никотинамида
|
|
UA103198C2
(en)
|
2008-08-04 |
2013-09-25 |
Новартис Аг |
Squaramide derivatives as cxcr2 antagonists
|
|
EP2350067A2
(en)
|
2008-10-16 |
2011-08-03 |
Schering Corporation |
Pyrrolidine, piperidine and piperazine derivatives and methods of use thereof
|
|
WO2010063802A1
(en)
|
2008-12-05 |
2010-06-10 |
Novartis Ag |
3, 4-di-substituted cyclobutene- 1, 2 -diones as cxcr2 receptor antagonists
|
|
WO2010091543A1
(en)
|
2009-02-10 |
2010-08-19 |
Merck Sharp & Dohme Corp. |
Novel hydrazino-cyclobut-3-ene-1, 2-dione derivatives as cxcr2 antagonists
|
|
WO2010131145A1
(en)
|
2009-05-12 |
2010-11-18 |
Pfizer Limited |
Cyclobutenedione derivatives
|
|
FR2961695B1
(fr)
|
2010-06-29 |
2012-07-06 |
Galderma Res & Dev |
Utilisation de composes dans le traitement ou la prevention de troubles cutanes
|
|
US8648070B2
(en)
|
2010-12-17 |
2014-02-11 |
Boehringer Ingelheim International Gmbh |
Bicyclic ring system substituted sulfonamide functionalised phenols as medicaments
|
|
US8648118B2
(en)
|
2010-12-17 |
2014-02-11 |
Boehringer Ingelheim International Gmbh |
Bicyclic ring system substituted amide functionalised phenols as medicaments
|
|
HUE035751T2
(hu)
|
2011-09-02 |
2018-08-28 |
Novartis Ag |
Gyulladásgátló szubsztituált ciklobuténdion vegyület kolinsó
|
|
FR2981934B1
(fr)
*
|
2011-10-28 |
2013-12-20 |
Galderma Res & Dev |
Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines.
|
|
FR2981936B1
(fr)
|
2011-10-28 |
2013-12-20 |
Galderma Res & Dev |
Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines.
|
|
FR2981935B1
(fr)
*
|
2011-10-28 |
2015-08-07 |
Galderma Res & Dev |
Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines.
|
|
KR102038310B1
(ko)
*
|
2011-11-16 |
2019-11-01 |
베링거 인겔하임 인터내셔날 게엠베하 |
항 il-36r 항체
|
|
JP2015522546A
(ja)
|
2012-05-23 |
2015-08-06 |
ステマージ バイオテクノロジー エスエー |
ミトコンドリア電子伝達鎖の複合体(iii)の活性の阻害剤およびその使用
|
|
WO2015170430A1
(ja)
*
|
2014-05-08 |
2015-11-12 |
学校法人慶應義塾 |
大動脈解離後の炎症性障害抑制剤
|
|
US20170320954A1
(en)
|
2014-11-17 |
2017-11-09 |
Medimmune Limited |
Therapeutic combinations and methods for treating neoplasia
|
|
TWI724056B
(zh)
|
2015-11-19 |
2021-04-11 |
美商卡默森屈有限公司 |
Cxcr2抑制劑
|
|
TWI734715B
(zh)
*
|
2015-11-19 |
2021-08-01 |
美商卡默森屈有限公司 |
趨化因子受體調節劑
|
|
IL275839B2
(en)
|
2018-01-08 |
2024-02-01 |
Chemocentryx Inc |
Methods for the treatment of generalized abscess psoriasis using a CCR6 or CXCR2 antagonist
|