JP7322036B2 - Ｃｃｒ６またはｃｘｃｒ２のアンタゴニストを用いて汎発性膿疱性乾癬を治療する方法 - Google Patents

Ｃｃｒ６またはｃｘｃｒ２のアンタゴニストを用いて汎発性膿疱性乾癬を治療する方法 Download PDF

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JP7322036B2
JP7322036B2 JP2020537663A JP2020537663A JP7322036B2 JP 7322036 B2 JP7322036 B2 JP 7322036B2 JP 2020537663 A JP2020537663 A JP 2020537663A JP 2020537663 A JP2020537663 A JP 2020537663A JP 7322036 B2 JP7322036 B2 JP 7322036B2
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ccr6
cxcr2
compound
cells
antagonist
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JPWO2019136370A5 (https=
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ジェイ．キャンベル ジェイムズ
エブスワース カレン
クラシンスキー アントーニ
レディー マリ ベンカット
マクマホン ジェフリー
シン ラジンダー
チュイ ヤン
チャオ ユイ
チャン ペングリー
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ケモセントリックス，インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2020537663A 2018-01-08 2019-01-07 Ｃｃｒ６またはｃｘｃｒ２のアンタゴニストを用いて汎発性膿疱性乾癬を治療する方法 Active JP7322036B2 (ja)

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US201862614927P 2018-01-08 2018-01-08
US62/614,927 2018-01-08
US201862715503P 2018-08-07 2018-08-07
US62/715,503 2018-08-07
PCT/US2019/012519 WO2019136370A2 (en) 2018-01-08 2019-01-07 Methods of treating generalized pustular psoriasis with an antagonist of ccr6 or cxcr2

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JP2021510160A JP2021510160A (ja) 2021-04-15
JPWO2019136370A5 JPWO2019136370A5 (https=) 2022-01-17
JP2021510160A5 JP2021510160A5 (https=) 2022-01-17
JP7322036B2 true JP7322036B2 (ja) 2023-08-07

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US (2) US11207294B2 (https=)
EP (1) EP3737366B1 (https=)
JP (1) JP7322036B2 (https=)
CN (1) CN111867579B (https=)
AU (1) AU2019205786B2 (https=)
IL (1) IL275839B2 (https=)
MA (1) MA50424A (https=)
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TWI724056B (zh) 2015-11-19 2021-04-11 美商卡默森屈有限公司 Ｃｘｃｒ２抑制劑
TWI734715B (zh) 2015-11-19 2021-08-01 美商卡默森屈有限公司 趨化因子受體調節劑
IL275839B2 (en) 2018-01-08 2024-02-01 Chemocentryx Inc Methods for the treatment of generalized abscess psoriasis using a CCR6 or CXCR2 antagonist
CN112190708B (zh) * 2019-07-08 2023-09-05 上海交通大学医学院附属瑞金医院 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用
BR112022021976A2 (pt) 2020-04-30 2022-12-13 Idorsia Pharmaceuticals Ltd Composto, e, composição farmacêutica compreendendo um composto
WO2023057548A1 (en) 2021-10-07 2023-04-13 Idorsia Pharmaceuticals Ltd Ccr6 receptor modulators
EP4423082A1 (en) 2021-10-26 2024-09-04 Idorsia Pharmaceuticals Ltd Ccr6 receptor modulators
KR20240090693A (ko) 2021-10-28 2024-06-21 이도르시아 파마슈티컬스 리미티드 Ccr6 수용체 조절인자

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CN111867579A (zh) 2020-10-30
IL275839B2 (en) 2024-02-01
CN111867579B (zh) 2023-11-24
US11684606B2 (en) 2023-06-27
US11207294B2 (en) 2021-12-28
EP3737366A2 (en) 2020-11-18
TWI821235B (zh) 2023-11-11
EP3737366B1 (en) 2026-02-25
JP2021510160A (ja) 2021-04-15
US20190209527A1 (en) 2019-07-11
EP3737366A4 (en) 2022-07-27
IL275839B1 (en) 2023-10-01
WO2019136370A3 (en) 2020-04-16
US20220280481A1 (en) 2022-09-08
WO2019136370A2 (en) 2019-07-11
IL275839A (en) 2020-08-31
AU2019205786A1 (en) 2020-08-06
EP3737366C0 (en) 2026-02-25
AU2019205786B2 (en) 2023-12-14
MA50424A (fr) 2020-08-26
CA3087701A1 (en) 2019-07-11
TW201936600A (zh) 2019-09-16

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