IL275839B2 - Methods for the treatment of generalized abscess psoriasis using a CCR6 or CXCR2 antagonist - Google Patents

Methods for the treatment of generalized abscess psoriasis using a CCR6 or CXCR2 antagonist

Info

Publication number
IL275839B2
IL275839B2 IL275839A IL27583920A IL275839B2 IL 275839 B2 IL275839 B2 IL 275839B2 IL 275839 A IL275839 A IL 275839A IL 27583920 A IL27583920 A IL 27583920A IL 275839 B2 IL275839 B2 IL 275839B2
Authority
IL
Israel
Prior art keywords
antagonist
ccr6
cxcr2
methods
pustular psoriasis
Prior art date
Application number
IL275839A
Other languages
English (en)
Hebrew (he)
Other versions
IL275839B1 (en
IL275839A (en
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Publication of IL275839A publication Critical patent/IL275839A/en
Publication of IL275839B1 publication Critical patent/IL275839B1/en
Publication of IL275839B2 publication Critical patent/IL275839B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL275839A 2018-01-08 2019-01-07 Methods for the treatment of generalized abscess psoriasis using a CCR6 or CXCR2 antagonist IL275839B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862614927P 2018-01-08 2018-01-08
US201862715503P 2018-08-07 2018-08-07
PCT/US2019/012519 WO2019136370A2 (en) 2018-01-08 2019-01-07 Methods of treating generalized pustular psoriasis with an antagonist of ccr6 or cxcr2

Publications (3)

Publication Number Publication Date
IL275839A IL275839A (en) 2020-08-31
IL275839B1 IL275839B1 (en) 2023-10-01
IL275839B2 true IL275839B2 (en) 2024-02-01

Family

ID=67140280

Family Applications (1)

Application Number Title Priority Date Filing Date
IL275839A IL275839B2 (en) 2018-01-08 2019-01-07 Methods for the treatment of generalized abscess psoriasis using a CCR6 or CXCR2 antagonist

Country Status (9)

Country Link
US (2) US11207294B2 (https=)
EP (1) EP3737366B1 (https=)
JP (1) JP7322036B2 (https=)
CN (1) CN111867579B (https=)
AU (1) AU2019205786B2 (https=)
IL (1) IL275839B2 (https=)
MA (1) MA50424A (https=)
TW (1) TWI821235B (https=)
WO (1) WO2019136370A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI724056B (zh) 2015-11-19 2021-04-11 美商卡默森屈有限公司 Ｃｘｃｒ２抑制劑
TWI734715B (zh) 2015-11-19 2021-08-01 美商卡默森屈有限公司 趨化因子受體調節劑
EP3737366B1 (en) 2018-01-08 2026-02-25 ChemoCentryx, Inc. Methods of treating generalized pustular psoriasis with an antagonist of ccr6 or cxcr2
CN117018202A (zh) * 2019-07-08 2023-11-10 上海交通大学医学院附属瑞金医院 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用
AU2021266148A1 (en) 2020-04-30 2023-01-05 Idorsia Pharmaceuticals Ltd Azetidin-3-ylmethanol derivatives as CCR6 receptor modulators
WO2023057548A1 (en) 2021-10-07 2023-04-13 Idorsia Pharmaceuticals Ltd Ccr6 receptor modulators
WO2023072924A1 (en) 2021-10-26 2023-05-04 Idorsia Pharmaceuticals Ltd Ccr6 receptor modulators
TW202325271A (zh) 2021-10-28 2023-07-01 瑞士商愛杜西亞製藥有限公司 Ccr6受體調節劑

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WO2017087610A1 (en) * 2015-11-19 2017-05-26 Chemocentryx, Inc. Inhibitors of cxcr2

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Also Published As

Publication number Publication date
EP3737366B1 (en) 2026-02-25
TWI821235B (zh) 2023-11-11
CN111867579A (zh) 2020-10-30
US11684606B2 (en) 2023-06-27
IL275839B1 (en) 2023-10-01
AU2019205786B2 (en) 2023-12-14
EP3737366C0 (en) 2026-02-25
WO2019136370A3 (en) 2020-04-16
IL275839A (en) 2020-08-31
MA50424A (fr) 2020-08-26
TW201936600A (zh) 2019-09-16
US11207294B2 (en) 2021-12-28
EP3737366A4 (en) 2022-07-27
CN111867579B (zh) 2023-11-24
JP2021510160A (ja) 2021-04-15
US20220280481A1 (en) 2022-09-08
AU2019205786A1 (en) 2020-08-06
CA3087701A1 (en) 2019-07-11
JP7322036B2 (ja) 2023-08-07
EP3737366A2 (en) 2020-11-18
US20190209527A1 (en) 2019-07-11
WO2019136370A2 (en) 2019-07-11

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