MA50424A - Méthodes de traitement du psoriasis pustuleux généralisé avec un antagoniste de ccr6 ou cxcr2 - Google Patents
Méthodes de traitement du psoriasis pustuleux généralisé avec un antagoniste de ccr6 ou cxcr2Info
- Publication number
- MA50424A MA50424A MA050424A MA50424A MA50424A MA 50424 A MA50424 A MA 50424A MA 050424 A MA050424 A MA 050424A MA 50424 A MA50424 A MA 50424A MA 50424 A MA50424 A MA 50424A
- Authority
- MA
- Morocco
- Prior art keywords
- ccr6
- methods
- cxcr2 antagonist
- treating generalized
- pustulous
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862614927P | 2018-01-08 | 2018-01-08 | |
US201862715503P | 2018-08-07 | 2018-08-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA50424A true MA50424A (fr) | 2020-08-26 |
Family
ID=67140280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA050424A MA50424A (fr) | 2018-01-08 | 2019-01-07 | Méthodes de traitement du psoriasis pustuleux généralisé avec un antagoniste de ccr6 ou cxcr2 |
Country Status (10)
Country | Link |
---|---|
US (2) | US11207294B2 (fr) |
EP (1) | EP3737366A4 (fr) |
JP (1) | JP7322036B2 (fr) |
CN (1) | CN111867579B (fr) |
AU (1) | AU2019205786B2 (fr) |
CA (1) | CA3087701A1 (fr) |
IL (1) | IL275839B2 (fr) |
MA (1) | MA50424A (fr) |
TW (1) | TWI821235B (fr) |
WO (1) | WO2019136370A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI734715B (zh) | 2015-11-19 | 2021-08-01 | 美商卡默森屈有限公司 | 趨化因子受體調節劑 |
TWI724056B (zh) | 2015-11-19 | 2021-04-11 | 美商卡默森屈有限公司 | Cxcr2抑制劑 |
US11207294B2 (en) | 2018-01-08 | 2021-12-28 | Chemocentryx, Inc. | Methods of treating generalized pustular psoriasis with an antagonist of CCR6 or CXCR2 |
CN117018202A (zh) * | 2019-07-08 | 2023-11-10 | 上海交通大学医学院附属瑞金医院 | 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用 |
JP2023523300A (ja) | 2020-04-30 | 2023-06-02 | イドーシア ファーマシューティカルズ リミテッド | Ccr6受容体調節剤としてのアゼチジン-3-イルメタノール誘導体 |
WO2023057548A1 (fr) | 2021-10-07 | 2023-04-13 | Idorsia Pharmaceuticals Ltd | Modulateurs du récepteur ccr6 |
TW202325278A (zh) | 2021-10-26 | 2023-07-01 | 瑞士商愛杜西亞製藥有限公司 | Ccr6受體調節劑 |
AR127486A1 (es) | 2021-10-28 | 2024-01-31 | Idorsia Pharmaceuticals Ltd | Moduladores del receptor ccr6 |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6166050A (en) | 1998-12-14 | 2000-12-26 | American Home Products Corporation | 3,4-diamino-3-cyclobutene-1,2-dione derivatives which inhibit leukocyte adhesion mediated by VLA-4 |
AR033803A1 (es) | 2000-03-01 | 2004-01-07 | Smithkline Beecham Corp | Compuestos de dianilino escuarano, composiciones farmaceuticas que los comprenden, y el uso de los mismos en la fabricacion de medicamentos para tratar enfermedades mediadas por quimioquinas |
HUP0302382A3 (en) | 2000-05-30 | 2004-09-28 | Smithkline Beecham Corp | Il-8 receptor antagonists and pharmaceutical compositions containing them |
JP2004521106A (ja) | 2001-01-16 | 2004-07-15 | スミスクライン・ビーチャム・コーポレイション | Il−8受容体アンタゴニスト |
ATE419845T1 (de) | 2001-01-16 | 2009-01-15 | Smithkline Beecham Corp | Il-8-rezeptor-antagonisten |
US20030204085A1 (en) | 2001-02-02 | 2003-10-30 | Taveras Arthur G. | 3, 4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor antagonists |
KR20030090629A (ko) | 2001-02-02 | 2003-11-28 | 쉐링 코포레이션 | Cxc 케모카인 수용체 길항제로서의 3,4-디-치환된사이클로부텐-1,2-디온 |
US7132445B2 (en) | 2001-04-16 | 2006-11-07 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
EP1381590B1 (fr) | 2001-04-16 | 2007-06-20 | Schering Corporation | Cyclobutène-1,2-diones disubstituées en positions 3,4 utilisées comme ligands de recepteurs de la chimiokine cxc |
US20040106794A1 (en) | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
US20040097547A1 (en) | 2001-04-16 | 2004-05-20 | Taveras Arthur G. | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
BR0308739A (pt) | 2002-03-18 | 2005-01-11 | Schering Corp | Tratamentos em combinação para doenças mediadas por quimiocina |
MXPA05011183A (es) | 2003-04-18 | 2005-12-14 | Schering Corp | Sintesis de 2-hidroxi-n, n-dimetil- 3-[[2-[1(r) -(5-metil -2-furanil) propil]amino]-3, 4-dioxo-1 -ciclobuten-1 -il]amino] benzamida. |
RU2388756C2 (ru) | 2004-01-30 | 2010-05-10 | Шеринг Корпорейшн | Кристаллические полиморфные формы лиганда схс-хемокинового рецептора |
US7521457B2 (en) | 2004-08-20 | 2009-04-21 | Boehringer Ingelheim International Gmbh | Pyrimidines as PLK inhibitors |
GB0419481D0 (en) | 2004-09-02 | 2004-10-06 | Cancer Rec Tech Ltd | Isoindolin-1-one derivatives |
DE102005035742A1 (de) | 2005-07-29 | 2007-02-01 | Merck Patent Gmbh | Quadratsäurederivate II |
JP2009542700A (ja) | 2006-07-07 | 2009-12-03 | シェーリング コーポレイション | Cxcケモカイン受容体リガンドとしての3,4−ジ置換シクロブテン−1,2−ジオン |
WO2008109177A2 (fr) | 2007-03-07 | 2008-09-12 | Alantos Pharmaceuticals Holding, Inc. | Inhibiteurs de métalloprotéase contenant une fraction hétérocyclique |
US8183281B2 (en) | 2007-06-06 | 2012-05-22 | Novartis Ag | CXC-chemokine receptor ligands |
EP2178826B1 (fr) | 2007-07-03 | 2017-05-17 | Merck Sharp & Dohme Corp. | Procédé et intermédiaires de synthèse de composés de 3,4-dioxo-1-cyclobutène 1,2-substitués |
CA2694268A1 (fr) | 2007-07-05 | 2009-01-08 | Schering Corporation | Procede pour obtenir une taille de cristaux controlee dans des composes 3,4-dioxo-1-cyclobutene 1,2-substitues |
WO2009012375A2 (fr) | 2007-07-19 | 2009-01-22 | Wyeth | Inhibiteurs de la squarate kinase |
EP2215074B1 (fr) | 2007-09-27 | 2014-02-19 | The United States of America, as Represented by the Secretary, Department of Health and Human Services | Composés d'isoindoline pour le traitement d'une amyotrophie spinale et autres utilisations |
MX2010006089A (es) | 2007-12-04 | 2010-09-22 | Schering Corp | Metodos de tratamiento de enfermedad pulmonar obstructiva cronica. |
WO2009156421A1 (fr) | 2008-06-24 | 2009-12-30 | Topotarget A/S | Dérivés de l’acide squarique utilisés comme inhibiteurs du nicotinamide |
UA103198C2 (en) | 2008-08-04 | 2013-09-25 | Новартис Аг | Squaramide derivatives as cxcr2 antagonists |
JP2012505898A (ja) | 2008-10-16 | 2012-03-08 | シェーリング コーポレイション | ピロリジン、ピペリジンおよびピペラジン誘導体ならびにそれらの使用方法 |
WO2010063802A1 (fr) | 2008-12-05 | 2010-06-10 | Novartis Ag | Cyclobutène-1,2-diones 3,4-disubstituées en tant qu'antagonistes de récepteur cxcr2 |
WO2010091543A1 (fr) | 2009-02-10 | 2010-08-19 | Merck Sharp & Dohme Corp. | Nouveaux dérivés d'hydrazinocyclobut-3-ène-1,2-dione comme antagonistes de cxcr2 |
WO2010131145A1 (fr) | 2009-05-12 | 2010-11-18 | Pfizer Limited | Dérivés de cyclobutène-dione |
FR2961695B1 (fr) | 2010-06-29 | 2012-07-06 | Galderma Res & Dev | Utilisation de composes dans le traitement ou la prevention de troubles cutanes |
US8648118B2 (en) | 2010-12-17 | 2014-02-11 | Boehringer Ingelheim International Gmbh | Bicyclic ring system substituted amide functionalised phenols as medicaments |
US8648070B2 (en) | 2010-12-17 | 2014-02-11 | Boehringer Ingelheim International Gmbh | Bicyclic ring system substituted sulfonamide functionalised phenols as medicaments |
EP3287438A1 (fr) | 2011-09-02 | 2018-02-28 | Novartis AG | Sel de choline d'un composé cyclobutène-dione substitué anti-inflammatoire |
FR2981934B1 (fr) * | 2011-10-28 | 2013-12-20 | Galderma Res & Dev | Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines. |
FR2981935B1 (fr) * | 2011-10-28 | 2015-08-07 | Galderma Res & Dev | Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines. |
FR2981936B1 (fr) | 2011-10-28 | 2013-12-20 | Galderma Res & Dev | Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines. |
KR20200110476A (ko) * | 2011-11-16 | 2020-09-23 | 베링거 인겔하임 인터내셔날 게엠베하 | 항 il-36r 항체 |
JP2015522546A (ja) | 2012-05-23 | 2015-08-06 | ステマージ バイオテクノロジー エスエー | ミトコンドリア電子伝達鎖の複合体(iii)の活性の阻害剤およびその使用 |
WO2015170430A1 (fr) * | 2014-05-08 | 2015-11-12 | 学校法人慶應義塾 | Agent inhibiteur des troubles inflammatoires subséquents à une dissection aortique |
WO2016079049A1 (fr) | 2014-11-17 | 2016-05-26 | Medimmune Limited | Combinaisons thérapeutiques et méthodes de traitement de la néoplasie |
TWI724056B (zh) * | 2015-11-19 | 2021-04-11 | 美商卡默森屈有限公司 | Cxcr2抑制劑 |
TWI734715B (zh) | 2015-11-19 | 2021-08-01 | 美商卡默森屈有限公司 | 趨化因子受體調節劑 |
US11207294B2 (en) | 2018-01-08 | 2021-12-28 | Chemocentryx, Inc. | Methods of treating generalized pustular psoriasis with an antagonist of CCR6 or CXCR2 |
-
2019
- 2019-01-07 US US16/241,469 patent/US11207294B2/en active Active
- 2019-01-07 AU AU2019205786A patent/AU2019205786B2/en active Active
- 2019-01-07 WO PCT/US2019/012519 patent/WO2019136370A2/fr active Application Filing
- 2019-01-07 IL IL275839A patent/IL275839B2/en unknown
- 2019-01-07 EP EP19736005.0A patent/EP3737366A4/fr active Pending
- 2019-01-07 CA CA3087701A patent/CA3087701A1/fr active Pending
- 2019-01-07 CN CN201980017463.XA patent/CN111867579B/zh active Active
- 2019-01-07 JP JP2020537663A patent/JP7322036B2/ja active Active
- 2019-01-07 MA MA050424A patent/MA50424A/fr unknown
- 2019-01-08 TW TW108100708A patent/TWI821235B/zh active
-
2021
- 2021-11-16 US US17/527,939 patent/US11684606B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
IL275839B2 (en) | 2024-02-01 |
AU2019205786A1 (en) | 2020-08-06 |
CA3087701A1 (fr) | 2019-07-11 |
WO2019136370A2 (fr) | 2019-07-11 |
US20190209527A1 (en) | 2019-07-11 |
IL275839B1 (en) | 2023-10-01 |
WO2019136370A3 (fr) | 2020-04-16 |
US20220280481A1 (en) | 2022-09-08 |
EP3737366A2 (fr) | 2020-11-18 |
CN111867579A (zh) | 2020-10-30 |
TW201936600A (zh) | 2019-09-16 |
AU2019205786B2 (en) | 2023-12-14 |
EP3737366A4 (fr) | 2022-07-27 |
US11207294B2 (en) | 2021-12-28 |
JP2021510160A (ja) | 2021-04-15 |
TWI821235B (zh) | 2023-11-11 |
IL275839A (en) | 2020-08-31 |
JP7322036B2 (ja) | 2023-08-07 |
US11684606B2 (en) | 2023-06-27 |
CN111867579B (zh) | 2023-11-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA50424A (fr) | Méthodes de traitement du psoriasis pustuleux généralisé avec un antagoniste de ccr6 ou cxcr2 | |
MA43817A (fr) | Méthodes de traitement de la dépression à l'aide d'antagonistes de récepteurs de l'orexine-2 | |
MA47820A (fr) | Traitement de la glycogénose de type iii | |
MA51525A (fr) | Traitement de minéraux | |
EP4070336A4 (fr) | Prédiction de la thrombo-embolie veineuse au moyen de modèles d'apprentissage automatique | |
MA56033A (fr) | Méthodes de traitement de la sclérodermie généralisée | |
MA52738A (fr) | Méthodes de traitement de l'arthrite psoriasique | |
DE112019004016T8 (de) | Hydraulikkreislauf einer baumaschine | |
ES1225190Y (es) | Conjunto de ducha | |
DK3208395T3 (da) | Afløbsarrangement til bruse- eller badekar | |
JP1713919S (ja) | 洗面台 | |
JP1712851S (ja) | 洗面台 | |
JP1710612S (ja) | 洗面台 | |
TH2102005655S (th) | ชุดฝักบัว | |
UA38358S (uk) | Набір перових свердел | |
UA38528S (uk) | Набір перових свердел | |
JP1721110S (ja) | たらい | |
JP1718665S (ja) | たらい | |
TH1902002339S (th) | ชุดฝักบัว | |
TH2102000784S (th) | อ่างล้างหน้า | |
UA44973S (uk) | Лійка для душу | |
UA44974S (uk) | Лійка для душу | |
TH2102005653S (th) | ฝักบัว | |
TH2102005609S (th) | ฝักบัว | |
ES1254511Y (es) | Ducha |