JPWO2023022216A5 - - Google Patents
Info
- Publication number
- JPWO2023022216A5 JPWO2023022216A5 JP2023542451A JP2023542451A JPWO2023022216A5 JP WO2023022216 A5 JPWO2023022216 A5 JP WO2023022216A5 JP 2023542451 A JP2023542451 A JP 2023542451A JP 2023542451 A JP2023542451 A JP 2023542451A JP WO2023022216 A5 JPWO2023022216 A5 JP WO2023022216A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- substituent group
- optionally substituted
- hydrogen
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021134801 | 2021-08-20 | ||
| PCT/JP2022/031308 WO2023022216A1 (ja) | 2021-08-20 | 2022-08-19 | ウイルス増殖抑制作用を有するヌクレオシド誘導体及びそれらのプロドラッグ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023022216A1 JPWO2023022216A1 (https=) | 2023-02-23 |
| JPWO2023022216A5 true JPWO2023022216A5 (https=) | 2025-08-18 |
Family
ID=85240607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023542451A Pending JPWO2023022216A1 (https=) | 2021-08-20 | 2022-08-19 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20250170155A1 (https=) |
| EP (1) | EP4389750A4 (https=) |
| JP (1) | JPWO2023022216A1 (https=) |
| KR (1) | KR20240050362A (https=) |
| CN (1) | CN118119624A (https=) |
| AU (1) | AU2022331233A1 (https=) |
| CA (1) | CA3229752A1 (https=) |
| CO (1) | CO2024003018A2 (https=) |
| IL (1) | IL310854A (https=) |
| MX (1) | MX2024002116A (https=) |
| PE (1) | PE20240654A1 (https=) |
| WO (1) | WO2023022216A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL300412A (en) | 2020-08-24 | 2023-04-01 | Gilead Sciences Inc | Phospholipid compounds and their uses |
| IL300453A (en) | 2020-08-27 | 2023-04-01 | Gilead Sciences Inc | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS |
| TW202344257A (zh) | 2020-10-16 | 2023-11-16 | 美商基利科學股份有限公司 | 磷脂化合物及其用途 |
| KR20240154647A (ko) | 2022-03-02 | 2024-10-25 | 길리애드 사이언시즈, 인코포레이티드 | 바이러스성 감염 치료를 위한 화합물 및 방법 |
| US12357577B1 (en) | 2024-02-02 | 2025-07-15 | Gilead Sciences, Inc. | Pharmaceutical formulations and uses thereof |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3277623D1 (en) | 1981-07-31 | 1987-12-17 | Sloan Kettering Inst Cancer | Anti-leukemic beta-glycosyl c-nucleosides |
| US5985848A (en) | 1997-10-14 | 1999-11-16 | Albert Einstein College Of Medicine Of Yeshiva University | Inhibitors of nucleoside metabolism |
| US7109331B2 (en) | 2000-08-29 | 2006-09-19 | Industrial Research Limited | 5H-pyrrolo[3,2-d]pyrimidine nucleoside metabolism inhibitors |
| US7098334B2 (en) | 2002-03-25 | 2006-08-29 | Industrial Research Limited | 4-amino-5H-pyrrolo[3,2-d]pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases |
| US20040063658A1 (en) | 2002-05-06 | 2004-04-01 | Roberts Christopher Don | Nucleoside derivatives for treating hepatitis C virus infection |
| EA014685B1 (ru) | 2003-04-25 | 2010-12-30 | Джилид Сайэнс, Инк. | Фосфонатсодержащие антивирусные соединения (варианты) и фармацевтическая композиция на их основе |
| CA2568379A1 (en) | 2004-06-15 | 2005-12-29 | Merck & Co., Inc. | C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase |
| US7560434B2 (en) | 2004-06-22 | 2009-07-14 | Biocryst Pharmaceuticals, Inc. | AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases |
| AU2005302448B2 (en) | 2004-10-29 | 2012-07-19 | Biocryst Pharmaceuticals, Inc. | Therapeutic furopyrimidines and thienopyrimidines |
| WO2007069924A1 (en) | 2005-12-15 | 2007-06-21 | Industrial Research Limited | Deazapurine analogs of 4'-aza-l-nucleosides |
| MX2009007333A (es) * | 2007-01-12 | 2009-08-31 | Biocryst Pharm Inc | Analogos de nucleosidos antivirales. |
| HRP20120914T1 (hr) | 2007-05-10 | 2012-12-31 | Biocryst Pharmaceuticals, Inc. | Spojevi tetrahidrofuro[3,4-d]dioksolana, namijenjeni upotrebi u lijeäśenju virusnih infekcija i raka |
| WO2010002877A2 (en) | 2008-07-03 | 2010-01-07 | Biota Scientific Management | Bycyclic nucleosides and nucleotides as therapeutic agents |
| TW201305185A (zh) | 2010-09-13 | 2013-02-01 | 吉李德科學股份有限公司 | 用於抗病毒治療之２’－氟取代之碳－核苷類似物 |
| US9290501B2 (en) | 2010-11-29 | 2016-03-22 | Albert Einstein College Of Medicine, Inc. | Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase |
| MD4496C1 (ro) * | 2012-03-13 | 2018-02-28 | Gilead Sciences, Inc. | Analogi carba-nucleozidici 2'-substituiţi pentru tratament antiviral |
| AR090699A1 (es) | 2012-04-18 | 2014-12-03 | Biocryst Pharm Inc | Compuestos inhibidores de la actividad de la arn polimerasa viral |
| WO2014035140A2 (en) | 2012-08-30 | 2014-03-06 | Kainos Medicine, Inc. | Compounds and compositions for modulating histone methyltransferase activity |
| WO2014093924A1 (en) | 2012-12-13 | 2014-06-19 | Moderna Therapeutics, Inc. | Modified nucleic acid molecules and uses thereof |
| JP2016504284A (ja) * | 2012-11-16 | 2016-02-12 | バイオクリスト ファーマスーティカルズ，インコーポレイテッドＢｉｏｃｒｙｓｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 抗ウイルス性アザ糖を含有するヌクレオシド |
| CA2911424C (en) | 2013-05-14 | 2021-11-30 | Biocryst Pharmaceuticals, Inc. | Anti-influenza imino-ribose pyrrolopyrimidine derivatives |
| UA119050C2 (uk) | 2013-11-11 | 2019-04-25 | Ґілеад Саєнсиз, Інк. | ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ |
| WO2015143712A1 (en) | 2014-03-28 | 2015-10-01 | Merck Sharp & Dohme Corp. | 4'-substituted nucleoside reverse transcriptase inhibitors |
| TWI687432B (zh) | 2014-10-29 | 2020-03-11 | 美商基利科學股份有限公司 | 絲狀病毒科病毒感染之治療 |
| CN107108683A (zh) | 2014-10-31 | 2017-08-29 | 共晶制药股份有限公司 | 用于治疗黄病毒科病毒和癌症的2’,2’‑二卤代核苷类似物 |
| CN110678473A (zh) | 2017-04-25 | 2020-01-10 | 大原药品工业株式会社 | 核苷类抗癌药或抗病毒药的5’位二苄基单磷酸酯衍生物 |
| WO2018230479A1 (ja) | 2017-06-13 | 2018-12-20 | 大原薬品工業株式会社 | ヌクレオシド系抗がん剤又は抗ウィルス剤の５'位シリルエーテル誘導体 |
| CA3075950A1 (en) * | 2017-09-18 | 2019-03-21 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| CA3126348A1 (en) | 2018-01-12 | 2020-07-18 | Board Of Regents Of The University Of Nebraska | Antiviral prodrugs and formulations thereof |
| WO2021040356A1 (en) | 2019-08-23 | 2021-03-04 | Kainos Medicine, Inc. | C-nucleosides, c-nucleotides and their analogs, equivalents and prodrugs thereof for ectonucleotidase inhibition |
| CN112778310B (zh) | 2020-04-20 | 2025-05-30 | 中国科学院上海药物研究所 | 核苷类似物或含有核苷类似物的组合制剂在抗病毒中的应用 |
| CN112062800B (zh) | 2020-09-02 | 2022-11-18 | 广东东阳光药业有限公司 | 核苷化合物的氨基磷酸酯衍生物及其用途 |
| CN112010916B (zh) | 2020-09-09 | 2022-12-27 | 广东东阳光药业有限公司 | 核苷化合物的氨基磷酸酯衍生物及其用途 |
-
2022
- 2022-08-19 EP EP22858533.7A patent/EP4389750A4/en active Pending
- 2022-08-19 MX MX2024002116A patent/MX2024002116A/es unknown
- 2022-08-19 JP JP2023542451A patent/JPWO2023022216A1/ja active Pending
- 2022-08-19 AU AU2022331233A patent/AU2022331233A1/en active Pending
- 2022-08-19 CA CA3229752A patent/CA3229752A1/en active Pending
- 2022-08-19 PE PE2024000272A patent/PE20240654A1/es unknown
- 2022-08-19 IL IL310854A patent/IL310854A/en unknown
- 2022-08-19 KR KR1020247008024A patent/KR20240050362A/ko active Pending
- 2022-08-19 CN CN202280069993.0A patent/CN118119624A/zh active Pending
- 2022-08-19 US US18/684,486 patent/US20250170155A1/en active Pending
- 2022-08-19 WO PCT/JP2022/031308 patent/WO2023022216A1/ja not_active Ceased
-
2024
- 2024-03-13 CO CONC2024/0003018A patent/CO2024003018A2/es unknown
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