|
JPH0395144A
(ja)
|
1989-08-04 |
1991-04-19 |
Ono Pharmaceut Co Ltd |
アミノフェノール誘導体の製造方法
|
|
JPH1129540A
(ja)
|
1997-07-04 |
1999-02-02 |
Showa Kako Kk |
エステル誘導体の製造方法
|
|
WO1999048880A1
(en)
|
1998-03-23 |
1999-09-30 |
Asahi Kasei Kogyo Kabushiki Kaisha |
Benzothiazolone-7-sulfonamide derivatives
|
|
US6316474B1
(en)
|
1999-10-29 |
2001-11-13 |
Merck & Co., Inc. |
2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
|
|
HN2001000008A
(es)
|
2000-01-21 |
2003-12-11 |
Inc Agouron Pharmaceuticals |
Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
|
|
GB0007884D0
(en)
|
2000-03-31 |
2000-05-17 |
Pfizer Ltd |
Diphenyl ether compounds useful in therapy
|
|
MXPA03001848A
(es)
|
2000-08-31 |
2003-06-04 |
Pfizer |
Derivados de fenoxibencilamina como inhibidores de la reabsorcion de serotonina.
|
|
US7087579B2
(en)
|
2001-02-26 |
2006-08-08 |
Kissei Pharmaceutical Co., Ltd. |
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
|
|
DK1859798T3
(en)
|
2001-03-29 |
2016-03-21 |
Lilly Co Eli |
N- (2-arylethyl) -BENZYLAMINER as antagonists of 5-HT6 receptor
|
|
GB0109103D0
(en)
|
2001-04-11 |
2001-05-30 |
Pfizer Ltd |
Novel compounds
|
|
JP2003321406A
(ja)
|
2002-04-30 |
2003-11-11 |
Mitsubishi Gas Chem Co Inc |
高純度フルオロアルキルベンゼン誘導体及びその製造法
|
|
US20040132708A1
(en)
|
2002-05-01 |
2004-07-08 |
Wyeth |
Process for preparing 6-alkylidene penem derivatives
|
|
AU2003235447A1
(en)
|
2002-05-31 |
2003-12-19 |
Banyu Pharmaceutical Co., Ltd. |
Method of substituent introduction through halogen-metal exchange reaction
|
|
ES2339112T3
(es)
|
2002-08-21 |
2010-05-17 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
8-(3-amino-piperidin-1-il)-xantinas,su preparacion y su uso como medicamentos.
|
|
US20040110802A1
(en)
|
2002-08-23 |
2004-06-10 |
Atli Thorarensen |
Antibacterial benzoic acid derivatives
|
|
EP1537074B1
(en)
|
2002-09-04 |
2019-02-27 |
Merck Canada Inc. |
Cathepsin cysteine protease inhibitors
|
|
US7256218B2
(en)
|
2002-11-22 |
2007-08-14 |
Jacobus Pharmaceutical Company, Inc. |
Biguanide and dihydrotriazine derivatives
|
|
TW200615273A
(en)
|
2004-11-10 |
2006-05-16 |
Nicholas Piramal India Ltd |
Fused tricyclic compounds as inhibitors of tumor necrosis factor-alpha
|
|
DK1836201T4
(da)
|
2004-12-20 |
2013-11-11 |
Genentech Inc |
Pyrrolidininhibitorer af IAP.
|
|
JP4794873B2
(ja)
|
2005-03-03 |
2011-10-19 |
富士フイルムファインケミカルズ株式会社 |
ハロゲン−リチウム交換反応を用いる有機化合物の製造法
|
|
KR20080002832A
(ko)
|
2005-03-16 |
2008-01-04 |
얀센 파마슈티카 엔.브이. |
보체 매개성 질병 및 이상을 치료하기 위한 신규한 티오펜설폭시민
|
|
TW200716104A
(en)
|
2005-06-01 |
2007-05-01 |
Wyeth Corp |
Tricyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
|
|
EP1893588A1
(en)
|
2005-06-10 |
2008-03-05 |
Boehringer Ingelheim International GmbH |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
JP2009502783A
(ja)
|
2005-07-20 |
2009-01-29 |
メルク エンド カムパニー インコーポレーテッド |
抗糖尿病性オキサゾリジンジオン及びチアゾリジンジオン
|
|
CA2619881A1
(en)
|
2005-08-16 |
2007-02-22 |
Genzyme Corporation |
Chemokine receptor binding compounds
|
|
WO2007047397A2
(en)
|
2005-10-13 |
2007-04-26 |
Smithkline Beecham Corporation |
Phenol ethers as modulators of the opioid receptors
|
|
WO2007061670A1
(en)
|
2005-11-21 |
2007-05-31 |
Amgen Inc. |
Beta-secretase modulators and methods of use
|
|
CA2637312A1
(en)
|
2006-01-27 |
2007-08-02 |
F. Hoffmann-La Roche Ag |
Use of substituted 2-imidazole of imidazoline derivatives
|
|
US7745477B2
(en)
|
2006-02-07 |
2010-06-29 |
Hoffman-La Roche Inc. |
Heteroaryl and benzyl amide compounds
|
|
CA2644368A1
(en)
|
2006-03-10 |
2007-09-20 |
Ono Pharmaceutical Co., Ltd. |
Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient
|
|
WO2007140005A2
(en)
|
2006-05-26 |
2007-12-06 |
Janssen Pharmaceutica N.V. |
Oxazolyl piperidine modulators of fatty acid amide hydrolase
|
|
ATE520651T1
(de)
|
2006-10-23 |
2011-09-15 |
Pfizer |
Substituierte phenylmethylbicyclocarbonsäureamidverbindungen
|
|
AU2007326395B2
(en)
|
2006-12-01 |
2012-10-11 |
Msd K.K. |
Novel phenyl-isoxazol-3-ol derivative
|
|
WO2008072726A1
(ja)
|
2006-12-14 |
2008-06-19 |
Taisho Pharmaceutical Co., Ltd. |
１－フェニル １－チオ－ｄ－グルシト－ル誘導体
|
|
TW200843739A
(en)
|
2007-03-30 |
2008-11-16 |
Shionogi & Co |
Novel pyrrolinone derivative and composition containing the same
|
|
TW200841879A
(en)
|
2007-04-27 |
2008-11-01 |
Eisai R&D Man Co Ltd |
Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
|
|
US20090227560A1
(en)
|
2007-04-27 |
2009-09-10 |
Takanobu Kuroita |
Substituted imidazole compound and use thereof
|
|
WO2008147544A1
(en)
|
2007-05-25 |
2008-12-04 |
Amgen Inc. |
Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use
|
|
WO2009004430A1
(en)
|
2007-06-29 |
2009-01-08 |
Pfizer Inc. |
N-benzyl oxazolidinones and related heterocycleic compounds as potentiators of glutamate receptors
|
|
WO2009051956A2
(en)
|
2007-10-16 |
2009-04-23 |
E. I. Du Pont De Nemours And Company |
Pyrazole-substituted isoxazoline insecticides
|
|
WO2009058921A1
(en)
|
2007-10-31 |
2009-05-07 |
Smithkline Beecham Corporation |
Ccr5 antagonists as therapeutic agents
|
|
JP2009120553A
(ja)
|
2007-11-16 |
2009-06-04 |
Taisho Pharmaceutical Co Ltd |
Ｃ−フェニルグルシト−ル化合物を有効成分とする糖尿病治療剤
|
|
CN101932577B
(zh)
|
2007-11-30 |
2013-07-17 |
拜耳知识产权有限责任公司 |
杂芳基取代的哌啶
|
|
US8134001B2
(en)
|
2007-12-14 |
2012-03-13 |
Hoffmann-La Roche Inc. |
Spiroindolinone derivatives
|
|
JP2009155212A
(ja)
|
2007-12-25 |
2009-07-16 |
Taisho Pharmaceutical Co Ltd |
Ｃ−フェニル１−チオグルシト−ル化合物を有効成分とする糖尿病治療剤
|
|
WO2009111676A2
(en)
|
2008-03-06 |
2009-09-11 |
Anacor Pharmaceuticals, Inc |
Boron-containing small molecules as anti-inflammatory agents
|
|
EP2254415B1
(en)
|
2008-02-19 |
2013-01-23 |
Janssen Pharmaceutica, N.V. |
Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase
|
|
US8633245B2
(en)
|
2008-04-11 |
2014-01-21 |
Institute Of Medicinal Molecular Design, Inc. |
PAI-1 inhibitor
|
|
EP2272817A4
(en)
|
2008-04-11 |
2011-12-14 |
Inst Med Molecular Design Inc |
PAI-1 INHIBITORS
|
|
US20110053949A1
(en)
|
2008-04-17 |
2011-03-03 |
Pfizer Inc. |
4-[3-(aryloxy)benzylidene]-3-methyl piperidine aryl carboxamide compounds useful as faah inhibitors
|
|
WO2009129625A1
(en)
|
2008-04-22 |
2009-10-29 |
Merck Frosst Canada Ltd. |
Novel substituted heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
|
MX2010012492A
(es)
|
2008-05-27 |
2010-12-21 |
Astrazeneca Ab |
Derivados de fenoxipiridinilamida y su uso en el tratamiento de estados de enfermedad mediados por fosfodiesterasa 4.
|
|
AU2009252615B2
(en)
|
2008-05-29 |
2013-08-15 |
Kowa Company, Ltd. |
Substituted carbinol compound having cyclic linker
|
|
US8071807B2
(en)
|
2008-07-03 |
2011-12-06 |
Panmira Pharmaceuticals, Llc |
Antagonists of prostaglandin D2 receptors
|
|
EP2318410A2
(en)
|
2008-07-09 |
2011-05-11 |
Envivo Pharmaceuticals, Inc. |
New small-molecule pde-10 inhibitors
|
|
WO2010021680A2
(en)
|
2008-08-19 |
2010-02-25 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of beta-secretase
|
|
TW201016702A
(en)
|
2008-09-25 |
2010-05-01 |
Shionogi & Co |
Novel pyrrolinone derivative and pharmaceutical composition comprising the same
|
|
WO2010123599A2
(en)
|
2009-01-23 |
2010-10-28 |
The Board Of Trustees Of The University Of Illinois |
Anti-bacterial compositions and methods including targeting virulence factors of staphylococcus aureus
|
|
PE20120578A1
(es)
|
2009-02-10 |
2012-06-17 |
Abbott Lab |
Agonistas y antagonistas del receptor de s1p5, y metodos de uso de los mismos
|
|
MY159575A
(en)
|
2009-04-02 |
2017-01-13 |
Merck Serono Sa |
Dihydroorotate dehydrogenase inhibitors
|
|
JP2012524800A
(ja)
|
2009-04-22 |
2012-10-18 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
モノアシルグリセロールリパーゼ阻害剤としてのアゼチジニルジアミド
|
|
US8906914B2
(en)
|
2009-08-18 |
2014-12-09 |
Janssen Pharmaceutica Nv |
Ethylene diamine modulators of fatty acid hydrolase
|
|
WO2011023753A1
(en)
|
2009-08-27 |
2011-03-03 |
Glaxo Group Limited |
Benzoxazine derivatives as glycine transport inhibitors
|
|
TW201139406A
(en)
|
2010-01-14 |
2011-11-16 |
Glaxo Group Ltd |
Voltage-gated sodium channel blockers
|
|
WO2011137024A1
(en)
|
2010-04-26 |
2011-11-03 |
Merck Sharp & Dohme Corp. |
Novel spiropiperidine prolylcarboxypeptidase inhibitors
|
|
DE102010030688A1
(de)
|
2010-06-30 |
2012-01-05 |
Bayer Schering Pharma Aktiengesellschaft |
Substituierte Dicyanopyridine und ihre Verwendung
|
|
GB201016880D0
(en)
|
2010-10-07 |
2010-11-17 |
Riotech Pharmaceuticals Ltd |
Phosphodiesterase inhibitors
|
|
CN103249721B
(zh)
|
2010-10-18 |
2016-10-12 |
拉夸里亚创药株式会社 |
作为ttx-s阻滞剂的芳胺衍生物
|
|
BR112013009828A2
(pt)
|
2010-10-22 |
2016-07-26 |
Janssen Pharmaceutica Nv |
diamidas de amino-pirrolidina-azetidina como inibidores de monoacilglicerol lipase
|
|
TWI396678B
(zh)
|
2010-12-07 |
2013-05-21 |
Nat Univ Tsing Hua |
二級醇製備方法
|
|
WO2012093174A1
(en)
|
2011-01-07 |
2012-07-12 |
Vivalis |
1-(6-membered azo-heterocyclic)-2,5-dihydro-1h-pyrrol-2-one derivatives as anti-hepatitis c virus, the pharmaceutical composition thereof and their therapeutic use
|
|
US8592426B2
(en)
|
2011-01-24 |
2013-11-26 |
Hoffmann—La Roche Inc. |
Aryl-benzocycloalkyl amide derivatives
|
|
FR2973487B1
(fr)
|
2011-03-31 |
2018-01-26 |
L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude |
Procede et appareil de production d'un gaz de l'air sous pression par distillation cryogenique
|
|
US9051333B2
(en)
|
2011-04-15 |
2015-06-09 |
Otsuka Pharmaceutical Co., Ltd. |
6,7-dihydroimidazo [2,1-b] [1,3]oxazine bactericides
|
|
EP2520556A1
(en)
|
2011-05-03 |
2012-11-07 |
Bayer Pharma Aktiengesellschaft |
Radiolabeled amino acids for diagnostic imaging
|
|
GB201113689D0
(en)
|
2011-08-09 |
2011-09-21 |
Amakem Nv |
Novel PDE4 inhibitors
|
|
AR087875A1
(es)
|
2011-09-16 |
2014-04-23 |
Actelion Pharmaceuticals Ltd |
Proceso para la elaboracion de derivados de piridazina como intermediarios de sintesis de antibioticos
|
|
GB201118334D0
(en)
|
2011-10-24 |
2011-12-07 |
Biotica Tech Ltd |
Novel dosage form
|
|
WO2013067302A1
(en)
|
2011-11-04 |
2013-05-10 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Method of treatment
|
|
EP2780014A4
(en)
|
2011-11-18 |
2015-07-01 |
Constellation Pharmaceuticals Inc |
MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
|
|
US8791091B2
(en)
|
2011-12-02 |
2014-07-29 |
Bristol-Myers Squibb Company |
Aryl dihydropyridinone and piperidinone MGAT2 inhibitors
|
|
MX360323B
(es)
|
2012-04-25 |
2018-10-29 |
Raqualia Pharma Inc |
Derivados de pirrolopiridinona como bloqueadores de ttx-s.
|
|
AR091023A1
(es)
|
2012-05-11 |
2014-12-30 |
Abbvie Inc |
Inhibidores del nampt
|
|
TWI585088B
(zh)
*
|
2012-06-04 |
2017-06-01 |
第一三共股份有限公司 |
作爲激酶抑制劑之咪唑并［１，２－ｂ］嗒衍生物
|
|
TWI583670B
(zh)
|
2012-07-30 |
2017-05-21 |
大正製藥股份有限公司 |
Partially saturated nitrogenous heterocyclic compounds
|
|
ES2661585T3
(es)
|
2012-10-31 |
2018-04-02 |
Raqualia Pharma Inc |
Derivados de pirazolopiridina como bloqueadores de TTX-S
|
|
JP2016028016A
(ja)
|
2012-12-12 |
2016-02-25 |
大日本住友製薬株式会社 |
オキサジアゾール誘導体とその医薬用途
|
|
US9834521B2
(en)
|
2013-03-15 |
2017-12-05 |
Ariad Pharmaceuticals, Inc. |
Choline kinase inhibitors
|
|
KR102214222B1
(ko)
|
2013-07-10 |
2021-02-08 |
메이지 세이카 파루마 가부시키가이샤 |
신규 pde4 저해제
|
|
EP2905282A1
(en)
|
2014-02-05 |
2015-08-12 |
AXXAM S.p.A. |
Substituted thiazole or oxazole as P2X7 receptor antagonists
|
|
AP2016009465A0
(en)
|
2014-04-01 |
2016-09-30 |
Pfizer |
Chromene and 1,1 a,2,7b-tetrahydrocyclopropa[c]chromene pyridopyrazinediones as gamma-secretase modulators
|
|
WO2015160665A1
(en)
|
2014-04-15 |
2015-10-22 |
Dow Agrosciences Llc |
Metalloenzyme inhibitor compounds as fungicides
|
|
WO2016019588A1
(en)
|
2014-08-08 |
2016-02-11 |
The Broad Institute, Inc. |
Oxacazone compounds to treat clostridium difficile
|
|
EP3204351A1
(en)
|
2014-10-08 |
2017-08-16 |
Dow Global Technologies LLC |
Method for coupling a fluorosulfonate compound with an amine compound
|
|
WO2016115282A1
(en)
|
2015-01-13 |
2016-07-21 |
Vanderbilt University |
Benzoisoxazole-substituted compounds as mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
|
|
CN105837576B
(zh)
|
2015-01-14 |
2019-03-26 |
湖北生物医药产业技术研究院有限公司 |
Btk抑制剂
|
|
US20180073084A1
(en)
|
2015-03-16 |
2018-03-15 |
Daiichi Sankyo Company, Limited |
Method for predicting responsiveness to phosphatidylserine synthase 1 inhibitor
|
|
EP3280709B1
(en)
|
2015-04-10 |
2021-05-26 |
FMC Corporation |
Substituted cyclic amides as herbicides
|
|
ES2735924T3
(es)
|
2015-04-17 |
2019-12-20 |
Dow Agrosciences Llc |
Moléculas que tienen utilidad plaguicida e intermediarios, composiciones y procesos, relacionados con ellas
|
|
CN104876936B
(zh)
*
|
2015-05-25 |
2018-01-30 |
中国人民解放军第二军医大学 |
吡咯酮并吡唑类化合物的制备及作为药物的用途
|
|
WO2017069601A1
(en)
|
2015-10-19 |
2017-04-27 |
Latvian Institute Of Organic Synthesis |
Substituted aminoalkylazoles as malarial aspartic protease inhibitors
|
|
US11319299B2
(en)
|
2016-03-01 |
2022-05-03 |
Propellon Therapeutics Inc. |
Substituted carboxamides as inhibitors of WDR5 protein-protein binding
|
|
WO2017197555A1
(en)
|
2016-05-16 |
2017-11-23 |
Merck Sharp & Dohme Corp. |
Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators
|
|
EP3538523B1
(en)
|
2016-11-08 |
2021-05-19 |
Cancer Research Technology Limited |
Pyrimidinone derivatives as cdc7 inhibitors
|