JPWO2020071407A5 - - Google Patents
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- Publication number
- JPWO2020071407A5 JPWO2020071407A5 JP2020550483A JP2020550483A JPWO2020071407A5 JP WO2020071407 A5 JPWO2020071407 A5 JP WO2020071407A5 JP 2020550483 A JP2020550483 A JP 2020550483A JP 2020550483 A JP2020550483 A JP 2020550483A JP WO2020071407 A5 JPWO2020071407 A5 JP WO2020071407A5
- Authority
- JP
- Japan
- Prior art keywords
- condensation agent
- production method
- rna molecule
- formula
- represented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018187767 | 2018-10-02 | ||
| JP2018187767 | 2018-10-02 | ||
| PCT/JP2019/038860 WO2020071407A1 (ja) | 2018-10-02 | 2019-10-02 | ヘアピン型一本鎖ｒｎａ分子の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2020071407A1 JPWO2020071407A1 (ja) | 2021-09-02 |
| JPWO2020071407A5 true JPWO2020071407A5 (enExample) | 2022-10-04 |
| JP7405086B2 JP7405086B2 (ja) | 2023-12-26 |
Family
ID=70055619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020550483A Active JP7405086B2 (ja) | 2018-10-02 | 2019-10-02 | ヘアピン型一本鎖ｒｎａ分子の製造方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11891602B2 (enExample) |
| EP (1) | EP3862431B1 (enExample) |
| JP (1) | JP7405086B2 (enExample) |
| KR (1) | KR20210069628A (enExample) |
| CN (1) | CN112673102A (enExample) |
| ES (1) | ES2981806T3 (enExample) |
| TW (1) | TWI848981B (enExample) |
| WO (1) | WO2020071407A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114685572B (zh) * | 2022-06-02 | 2022-08-30 | 上海百力格生物技术有限公司 | 用于mgb核酸探针合成的氧化剂组合物及探针的合成方法 |
| WO2024112876A2 (en) * | 2022-11-23 | 2024-05-30 | Prime Medicine, Inc. | Split synthesis of long rnas |
| CN117143179B (zh) * | 2023-09-18 | 2024-07-12 | 安徽峆一药业股份有限公司 | 一种凝血酶发色底物s-2238的合成方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994007910A1 (en) | 1992-09-28 | 1994-04-14 | Research Corporation Technologies, Inc. | New reagents for peptide couplings |
| DE60014542T2 (de) | 1999-03-08 | 2006-03-09 | Tokuyama Corp., Tokuyama | Ein verfahren zur herstellung von carbonsäure-derivaten und ein kondensationshilfsmittel mit einem quarternären ammonium-salz |
| US6825347B2 (en) | 2001-05-21 | 2004-11-30 | Research Corporation Technologies, Inc. | Uronium and immonium salts for peptide coupling |
| AU2003256857A1 (en) | 2002-08-08 | 2004-02-25 | Dharmacon, Inc. | Short interfering rnas having a hairpin structure containing a non-nucleotide loop |
| JP5046002B2 (ja) | 2007-03-02 | 2012-10-10 | 公益財団法人新産業創造研究機構 | 塩化トリアジン誘導体、その製造方法およびその使用 |
| SG186899A1 (en) | 2010-07-08 | 2013-02-28 | Bonac Corp | Single-strand nucleic acid molecule for controlling gene expression |
| ES2533129T3 (es) | 2010-08-03 | 2015-04-07 | Bonac Corporation | Molécula de ARN monocatenario que tiene esqueleto alicíclico que contiene nitrógeno |
| WO2013103146A1 (ja) | 2012-01-07 | 2013-07-11 | 株式会社ボナック | アミノ酸骨格を有する一本鎖核酸分子 |
| JP2013153736A (ja) | 2012-01-07 | 2013-08-15 | Bonac Corp | ペプチド骨格を有する一本鎖核酸分子 |
| EP3254700B1 (en) * | 2012-03-04 | 2019-10-23 | Bonac Corporation | Micro-rna inhibitor |
| WO2015093495A1 (ja) * | 2013-12-16 | 2015-06-25 | 株式会社ボナック | ＴＧＦ－β１遺伝子発現制御のための一本鎖核酸分子 |
| JP6486700B2 (ja) | 2015-01-29 | 2019-03-20 | 国立大学法人金沢大学 | 脱水縮合剤 |
| JP6486699B2 (ja) | 2015-01-29 | 2019-03-20 | 国立大学法人金沢大学 | 脱水縮合剤 |
| WO2017035090A1 (en) | 2015-08-21 | 2017-03-02 | Thomas Jefferson University | Dumbbell-pcr: a method to quantify specific small rna variants with a single nucleotide resolution at terminal sequences |
| JP2018187767A (ja) | 2015-09-29 | 2018-11-29 | 綜研化学株式会社 | 撥水性部材及びその製造方法 |
| EP3369816B1 (en) * | 2015-10-30 | 2024-03-13 | Toray Industries, Inc. | Composition stably containing single-stranded nucleic acid molecule that suppresses expression of tgf-beta1 gene |
| JP6742606B2 (ja) | 2016-02-25 | 2020-08-19 | 国立大学法人金沢大学 | トリアジン含有ポリマー、その製造方法、及びその脱水縮合剤としての用途 |
| US20210115485A1 (en) * | 2018-03-30 | 2021-04-22 | Sumitomo Chemical Company, Limited | Method for producing single-strand rna |
| EP3778886A4 (en) * | 2018-03-30 | 2022-11-02 | Toray Industries, Inc. | Method for producing hairpin single-stranded rna molecule |
-
2019
- 2019-10-02 CN CN201980061140.0A patent/CN112673102A/zh active Pending
- 2019-10-02 JP JP2020550483A patent/JP7405086B2/ja active Active
- 2019-10-02 US US17/276,194 patent/US11891602B2/en active Active
- 2019-10-02 TW TW108135638A patent/TWI848981B/zh not_active IP Right Cessation
- 2019-10-02 EP EP19869898.7A patent/EP3862431B1/en active Active
- 2019-10-02 WO PCT/JP2019/038860 patent/WO2020071407A1/ja not_active Ceased
- 2019-10-02 ES ES19869898T patent/ES2981806T3/es active Active
- 2019-10-02 KR KR1020217007240A patent/KR20210069628A/ko active Pending
-
2023
- 2023-09-01 US US18/459,505 patent/US20240110186A1/en not_active Abandoned
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